Prevalence of vitamin D inadequacy in European postmenopausal women

Bruyère, Olivier; Malaise, Olivier; Neuprez, Audrey; Collette, Julien; Reginster, Jean‐Yves

doi:10.1185/030079907x219562

Cited by 82 publications

(52 citation statements)

References 38 publications

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“…Only every tenth subject had sufficient vitamin D concentration. This confirms the findings of a number of studies carried out in other countries, especially in northern countries, during winter [16,28,29]; the exception is Norway and other Scandinavian countries, where a regular usage of cod-liver supplements and fish products in the diet is usual [30].…”

Section: Discussionsupporting

confidence: 88%

Vitamin D deficiency is related to worse emotional state

et al. 2011

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AbstractThe aim was to evaluate vitamin D levels in young healthy Lithuanian males in winter and to find possible associations of vitamin D concentration to body composition, cognitive functioning, emotional state.Subjects and Methods A total of 130 healthy males (age range, 18–26 years) were divided into the subgroups according to vitamin D concentration. The Profile of Mood States (POMS) questionnaire and Hospital Anxiety and Depression Scale were employed in the assessment of emotional state. Cognitive functioning was assessed by the Trail Making Test and the Digit Symbol Test of the Wechsler Adult Intelligence Scale.Results The mean concentration of vitamin D for the entire sample was 13.0±5.3 ng/ml. Only 2 persons (1.6%) had the recommended vitamin D level. Nearly half (45.4%) of study participants had vitamin D deficiency. Lower concentrations were associated with a significantly higher score on the POMS confusion-bewilderment scale. A tendency toward a lower mean depression-dejection score in the participants with a sufficient vitamin D level was observed. Vitamin D concentration correlated positively with body mass index (BMI) and inversely with the confusion-bewilderment score.In conclusion almost half of the young healthy males participating in the study were detected to have vitamin D deficiency in winter. Low vitamin D concentrations are associated with a worse emotional state.

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Section: Discussionsupporting

confidence: 88%

Vitamin D deficiency is related to worse emotional state

et al. 2011

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“…However, it was less than what was reported by Bruyere et al (79.6%) [25] and higher than the results from Gorgan (Iran) by Marjani and Moghasemi (30%) [2,24,25].…”

Section: Discussioncontrasting

confidence: 55%

Serum Vitamin D and the Metabolic Syndrome Among Osteoporotic Postmenopausal Female Patients of a Family Practice Clinic in Jordan

2015

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Background. Vitamin D deficiency and insufficiency and the metabolic syndrome are two common health issues worldwide. The association between these two health problems is subject to debate. Objectives. This study aims to investigate the association between vitamin D deficiency or insufficiency and the metabolic syndrome in a sample of osteoporotic postmenopausal women attending a family practice clinic in Amman -Jordan. Material and Methods. This was an observational cross sectional study. It was carried out in the family practice clinic in Jordan University Hospital. The study included all postmenopausal osteoporotic women attending the clinic between June 2011 and May 2012, yielding a total of 326 subjects. The association between metabolic syndrome and serum vitamin D levels was investigated. Results. Waist circumference, body mass index, triglycerides and fasting blood sugar were significantly higher among postmenopausal women with metabolic syndrome, but HDL cholesterol was significantly lower (p < 0.05). The prevalence of metabolic syndrome among all study participants was 42.9%. Triglycerides and LDL cholesterol were significantly higher among women deficiency or insufficiency (p < 0.05). The prevalence of vitamin D deficiency or insufficiency was 45.7%. Among patients with metabolic syndrome, the prevalence of vitamin D deficiency or insufficiency was 50.7%. Conclusions. Findings of the current study suggest a lack of relationship between serum vitamin D and metabolic syndrome. However, a significant inverse relationship was found between serum vitamin D levels and both serum triglycerides and LDL levels (Adv Clin Exp Med 2015, 24, 2, 245-250).

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“…In adult population, the prevalence of hypovitaminosis D ranges from 5% to 30%,7 but it reaches a peak of 75% in patients with MS 8. Vitamin D‐deficient individuals are more likely to develop alterations in glucose metabolism, such as impaired glucose tolerance, MS, and type 2 diabetes mellitus (DM) 9.…”

Section: Introductionmentioning

confidence: 99%

Vitamin D supplementation in patients with nonalcoholic fatty liver disease: A randomized controlled trial

et al. 2017

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Background and AimDeficiency of vitamin D may be related to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). The aim of the present study was to evaluate the effect of vitamin D supplementation in patients with NAFLD.MethodsA total of 81 patients with NAFLD with normal or raised (n = 47) serum alanine aminotransferase (ALT) having vitamin D deficiency were randomized prospectively. Group 1 (n = 51) received lifestyle modifications and a single injection of vitamin D (600 000 U) (standard medical treatment [SMT] + vitamin D) and group 2 (n = 30) received lifestyle modifications (SMT) for 6 months. The primary objective of this study was to assess the improvement in insulin resistance (IR) and serum ALT (in patients with raised ALT) and the secondary objective was to assess the change in cytokine profile in the SMT + vitamin D group.ResultsAfter 6 months, significant improvement in serum levels of ALT was observed in the SMT + vitamin D group when compared to the SMT group (ALT [87 ± 48 and 59 ± 32 IU/mL, P < 0.001] vs [64 ± 35 and 62 ± 24 IU/mL, P = 0.70]). Mean insulin levels and homeostasis model assessment‐IR remained unchanged at 6 months in the SMT + vitamin D group while there was a significant increase in mean insulin and homeostasis model assessment‐IR in the SMT group. SMT + vitamin D group had significant increase in mean serum levels of adiponectin (836 ± 309 and 908 ± 312 (pg/mL), P = 0.018) compared with the baseline; tumor necrosis factor‐α levels decreased from baseline but the change was not significant.ConclusionPatients with NAFLD given vitamin D in addition to lifestyle modifications have significant improvement in serum ALT and serum adiponectin levels.

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Prevalence of vitamin D inadequacy in European postmenopausal women

Abstract: This study indicates a high prevalence of vitamin D [25(OH)D] inadequacy in European postmenopausal women. The prevalence could be even higher in some particular countries. A greater awareness of the importance of vitamin D inadequacy is needed to address this public health problem.

Cited by 82 publications

References 38 publications

Vitamin D deficiency is related to worse emotional state

Vitamin D deficiency is related to worse emotional state

Serum Vitamin D and the Metabolic Syndrome Among Osteoporotic Postmenopausal Female Patients of a Family Practice Clinic in Jordan

Vitamin D supplementation in patients with nonalcoholic fatty liver disease: A randomized controlled trial

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