Prevalence of vitamin D and calcium deficiencies and their health impacts on women of childbearing age: a protocol for systematic review and meta-analysis

Silveira, Érika Aparecida; Moura, Letícia de Almeida Nogueira e; Castro, Maria Clara Rezende; Kac, Gilberto; Noll, Priscilla Rayanne e Silva; Oliveira, César de

doi:10.1136/bmjopen-2021-049731

Cited by 1 publication

(2 citation statements)

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“…This review follows the PICO structure, with “P” (population) being women of childbearing age, “I” being no intervention, “C” being comparison between pregnant and non-pregnant subgroups and region, and “O” (outcome) being the prevalence calcium and vitamin D deficiency. The protocol (CRD42020207850) of this systematic review was registered on the PROSPERO platform and published under the title Prevalence of vitamin D and calcium deficiencies and their health impacts on women of childbearing age: a protocol for systematic review and meta-analysis [ 31 ].…”

Section: Methodsmentioning

confidence: 99%

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Prevalence of Vitamin D and Calcium Deficiency and Insufficiency in Women of Childbearing Age and Associated Risk Factors: A Systematic Review and Meta-Analysis

et al. 2022

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Vitamin D deficiency and insufficiency as well as low serum calcium levels can trigger negative health outcomes in women of childbearing age. Therefore, we aimed to estimate the prevalence of serum vitamin D and calcium deficiencies and insufficiencies and associated risk factors in Brazilian women of childbearing age and to assess whether there are differences in prevalence according to regions of the country and the presence or absence of pregnancy. The systematic literature review was performed using the following databases: PubMed, LILACS, Embase, Scopus, and Web of Science. Cross-sectional, cohort, and intervention studies were included. Among pregnant women, the prevalence of vitamin D deficiency ranged from 0% to 27% and of vitamin D insufficiency from 33.9% to 70.4%. Among non-pregnant women, the prevalence of vitamin D deficiency ranged from 0% to 41.7% and of vitamin D insufficiency from 38.5% to 69.3%. We found a high prevalence of vitamin D deficiency and insufficiency in women of childbearing age, with insufficiency affecting more than half of these women. The highest prevalence of vitamin D deficiency and insufficiency was observed in the South region. It was not possible to assess the prevalence and factors associated with calcium deficiency.

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Section: Methodsmentioning

confidence: 99%

“…The search strategy included relevant keywords related to vitamin D deficiency and specific terms related to calcium deficiency to ensure that all articles of interest were identified. Details describing the entire methodology and search strategy with the terms are published in the protocol article [ 31 ].…”

Section: Methodsmentioning

confidence: 99%