Prevalence of UTI causing pathogens among different subgroups of the local population

Abstract

The Urinary Tract Infection (UTI) is one of the most frequent and contagious infection, caused by range of pathogens, affecting an estimated 150 million people around the globe every year. The current study has investigated the prevalence of UTI among the local population of Pakistan. The urine samples of 200 patients were collected based on different UTI related symptoms and the infection was detected through quantitative urine culture and microscopic enumeration of urine leukocytes. Then UTI causing pathogens were isolated from positive samples and their sensitivity against antibiotics was checked through antimicrobial susceptibility method. The E.coli was the most predominant uropathogen found among all the positive samples followed by Klebsiella, Staphylococcus, Pseudomonas, Acinetobacter, Proteus species, and Enterococcus. The comparative analysis of UTI between both males and females showed that UTI is highly prevalent among female patients as compared to males especially in adult age ranges from 21-30 years due to hormonal changes and pregnancy. All the isolated pathogens were differentially sensitive against conventional antibiotics but they showed highest sensitivity against imipenem while highest resistivity against ampicillin. This study has also shown that the excessive use of antibiotics leads to the drug resistance and increases the chance of any bacterial infection.