Abstract:Methods: Protein lysates and RNA prepared from cardiac muscle from colon 26 (C26) carcinoma bearing mice at day 14 post-tumour inoculation (i.e. 15-20% total body weight loss = overt cachexia) was used in this study. Gene and protein expression studies using quantitative Real Time Polymerase Chain Reaction (qRT-PCR) and Western blotting were performed on novel candidate markers of CC in heart, which may potentially be underpinning this process.Results: There was a significant up-regulation of RNA for Similar t… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.