Prevalence of undiagnosed hypertension among a cohort of university workers in Nigeria

Vincent-Onabajo, Grace; Mohammad, Habiba Suleiman; Umeonwuka, Chuka

doi:10.18203/2394-6040.ijcmph20162073

Cited by 13 publications

(17 citation statements)

References 15 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The burden of hypertension and diabetes in Nigeria is high with national prevalence of 28.9% and 5.77% respectively [ 21 , 22 ]. There are still a lot of undiagnosed cases as a result of lack of awareness and poor health seeking behavior of the population [ 22 , 23 ]. As a result, many patients present with uncontrolled diseases with attending complications [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

et al. 2021

View full text Add to dashboard Cite

Background Data on the comorbidities that result in negative outcomes for people with COVID-19 are currently scarce for African populations. This study identifies comorbidities that predict death among a large sample of COVID-19 patients from Nigeria. Methods This was a retrospective analysis of medical records for 2184 laboratory confirmed cases of COVID-19 in Lagos, southwest Nigeria. Extracted data included age, sex, severity of condition at presentation and self-reported comorbidities. The outcomes of interest were death or discharge from facility. Results Most of the cases were male (65.8%) and the median age was 43 years (IQR: 33–55). Four hundred and ninety-two patients (22.5%) had at least one comorbidity and the most common amongst them were hypertension (74.2%) and diabetes (30.3%). The mortality rate was 3.3% and a significantly higher proportion of patients with comorbidities died compared to those with none. The comorbidities that predicted death were hypertension (OR: 2.21, 95%CI: 1.22–4.01), diabetes (OR: 3.69, 95% CI: 1.99–6.85), renal disease (OR: 12.53, 95%CI: 1.97–79.56), cancer (OR: 14.12, 95% CI: 2.03–98.19) and HIV (OR: 1.77–84.15]. Conclusion Comorbidities are prevalent and the associated risk of death is high among COVID-19 patients in Lagos, Nigeria. Public enlightenment, early identification and targeted care for COVID-19 cases with comorbidities are recommended as the pandemic evolves.

show abstract

Section: Discussionmentioning

confidence: 99%

Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Unlike study reports from northern India, 15 Sudan, 17 Nigeria 22 and Addis Ababa, Ethiopia, 19 in the current study, the age of the study participants did not show an association with undiagnosed HTN. However, we found an increased risk of undiagnosed HTN among male participants compared to females.…”

Section: Discussionmentioning

confidence: 99%

“…This was in agreement with the study findings from Gondar city in north-west Ethiopia, 36 Durame town in southern Ethiopia, 31 India 15 and Nigeria. 22 High BMI is a well-known risk factor of HTN. 37 It is important to teach people with high BMI to use interventions which could reduce their BMI and to check their BP regularly to reduce the risk of undiagnosed HTN and its consequences.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Undiagnosed Hypertension and Associated Factors Among Adults in Hawela Tula Sub-City, Hawassa, Southern Ethiopia: A Community-Based Cross-Sectional Study</p>

Wachamo

Geleta

Woldesemayat

2020

RMHP

View full text Add to dashboard Cite

Background: Hypertension (HTN) is a major public health problem and often it is unnoticed. Undiagnosed HTN may lead to a high burden of cardiovascular diseases and complications such as stroke and heart attack. In this study, we aimed to assess the prevalence and associated factors of undiagnosed HTN. Methods: From February to June 2019, a community-based cross-sectional study was conducted on 383 randomly selected adults in Hawela Tulla Sub-city, Hawassa, southern Ethiopia. Data were collected by pretested questionnaires, and physical measurements of weight, height and blood pressure were collected through standardized procedures adapted from WHO STEPS survey tools. Data entry and analysis were carried out using SPSS version 23 statistical software. Descriptive analysis and logistic regression models were used to describe the results. Logistic regression analysis results were declared statistically significant if the P-value was below 0.05 and the 95% CI did not cross the null value. Results: The prevalence of undiagnosed HTN among the respondents was 12.3%. Only 152 (39.7%) of the study population knew the symptoms of HTN. Males (adjusted odds ratio [AOR] =2.

show abstract

“…Hypertension is a risk factor for cardiovascular disease and stroke which in turn is one of the leading causes of death across the world (Nawaz et al, 2017). Due to its asymptomatic nature coupled with lackadaisical attitude of some patients towards health and well-being, many hypertensive patients are not aware of it (Vincent-Onabajo et al, 2017). Blood pressure is mainly controlled by renin angiotensin aldosterone system (RAAS).…”

Section: Introductionmentioning

confidence: 99%

Renin-Inhibitory Bioactive Peptides With Antihypertensive Property: A Review

Mada

Ugwu

Abarshi³

et al. 2020

FJS

View full text Add to dashboard Cite

Blood pressure is regulated by the renin angiotensin aldosterone system (RAAS). Renin-catalyzed conversion of angiotensinogen to angiotensin I is the rate-limiting step of the RAAS pathway, which arguably makes renin a better target for prevention, treatment and management of hypertension than Angiotensin-Converting Enzyme (ACE). Hydrolysis of food proteins releases bioactive peptides that can interact with receptors, enzymes and molecules in the organism to promote health. Several studies have shown that these bioactive peptides could be exploited for management of hypertension which is a major risk factor for cardiovascular diseases (CVDs). Antihypertensive peptides are bioactive peptides derived from plant and animal sources with inherent potential to ameliorate hypertension by different mechanism including scavenging of free radicals, reduced cholesterol level, inhibit angiotensin-converting enzyme (ACE) activity and renin production. Although there was sufficient information on ACE-inhibitory and antioxidative peptides while information on the potential role of renin-inhibitory peptides against hypertension is limited. Thus, herein the present review primarily used ISI, SCOPUS and PubMed indexed journals containing experimental reports to elucidate the potential role of bioactive peptides against antihypertensive effect via renin inhibition. Key words: Hypertension; Bioactive peptides; Renin inhibition; Mechanism of action.

show abstract

Prevalence of undiagnosed hypertension among a cohort of university workers in Nigeria

Cited by 13 publications

References 15 publications

Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

<p>Undiagnosed Hypertension and Associated Factors Among Adults in Hawela Tula Sub-City, Hawassa, Southern Ethiopia: A Community-Based Cross-Sectional Study</p>

Renin-Inhibitory Bioactive Peptides With Antihypertensive Property: A Review

Contact Info

Product

Resources

About