Prevalence of temporomandibular disorders in subjects affected by Parkinson disease: A systematic review and metanalysis

Abstract

Introduction: While Temporomandibular disorders (TMDs) are not typically considered a primary symptom of Parkinson disease (PD), recent studies have documented a correlation between ageing and TMDs, a cluster of conditions affecting the temporomandibular joint and surrounding musculature, thereby underscoring the potential for an increased frequency of TMDs in the ageing PD population. Objective: The purpose of this review is to systematically evaluate the existing literature on the topic and provide a comprehensive overview of the prevalence of TMDs in patients with PD. Methods: To determine eligibility, we utilised the Population (human subjects), Exposure (PD), Comparator (PD vs non-PD subjects), and Outcomes (TMD) (PECO) model. To conduct this systematic review, we searched for articles published in PubMed, Web of Science and Lilacs from the beginning until April 15, 2023.Results: Three studies were selected. All together they comprised a total of 55 828 subjects, out of which 12 629 were affected by PD or Parkinsonism, and the remaining 43 199 were non-PD subjects matched for age and sex. The study aimed to evaluate the prevalence of TMDs in subjects affected by PD. The results showed that 193/12629 (1.53%) of PD individuals presented with TMD symptoms or were diagnosed with TMD, while 260/43199 (0.6%) of non-PD subjects were diagnosed with the same. The meta-analysis showed that there was a higher TMD prevalence in PD subjects compared to non-PD subjects (RR 1.57; 95% CI: 1.30-1.89). Conclusion:The studies reviewed suggest a possible association between TMD and PD. Further research is needed to clarify the relationship between TMD and PD and to identify possible mechanisms and treatment strategies.

Early Soft Tissue Response to Immediate Monotype Zirconia Implant: A Metal-Free Restoration

“…The case report illustrated zirconia implants' benefits regarding biocompatibility, esthetic outcomes, and biomechanical/occlusal stability. 22 23 24 25…”

Post‐traumatic stress, prevalence of temporomandibular disorders in war veterans: Systematic review with meta‐analysis

“…Chronic stress can disrupt the body's physiological processes, leading to inflammation, oxidative stress and alterations in hormones and immune function, which in turn increase the risk of developing chronic diseases. [1][2][3][4] War is a major source of stress exposure, as it involves exposure to traumatic events, fear and loss, which can result in long-term psychological distress and increase the risk of developing physical and mental health diseases. 1 The physical and psychological effects of war are not always easy to detect, but they can be far-reaching and long-lasting.…”

“…Stress exposure has been linked to a variety of chronic diseases, including cardiovascular disease, neurologic diseases and mental health disorders. Chronic stress can disrupt the body's physiological processes, leading to inflammation, oxidative stress and alterations in hormones and immune function, which in turn increase the risk of developing chronic diseases 1–4 …”

Prevalence of temporomandibular disorders in clear aligner patients using orthodontic intermaxillary elastics assessed with diagnostic criteria for temporomandibular disorders (DC/TMD) axis II evaluation: A cross‐sectional study

“…According to the available literature, DC/TMD is the preferred method for assessing TMD. [12][13][14][15] The available evidence indicates that the utilisation of Class II and Class III elastics may have an impact on the TMJ; however, the degree of influence may differ. 1,16 According to a study conducted by Sambataro et al, elastics have an impact not only on the teeth but also on the TMJ position.…”

“…Consequently, through comprehensive research efforts, the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) was developed as an updated version of the RDC/TMD. According to the available literature, DC/TMD is the preferred method for assessing TMD 12–15 …”