Prevalence of stroke/cardiovascular risk factors in Hungary

Sipos, Kornel; Thuróczy, György; Pánczél, Gyula; Ilias, LM; P, Szonyi; Bodó, Michael; Nebella, T; Banyasz, A; Nagy, Zoltán

doi:10.1088/1742-6596/224/1/012115

Cited by 5 publications

(10 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additional data for correlation of CVD risk factors were detailed elsewhere [40]. Conclusion: In this study REG measurements revealed symptoms of arteriosclerosis in 54.26 % of our subjects; within the identical population, the Doppler ultrasound measurements showed 30.43 % with arteriosclerosis.…”

Section: Cerberus Measurementsupporting

confidence: 57%

“…The analyzed REG sample involved 457 subjects, 309 female and 148 male. Psychological tests and comparative analysis were part of the full protocol; detailed elsewhere [39,40].…”

Section: A Comparative Population Screening With Cerberus Systemmentioning

confidence: 99%

“…Mean velocity for "out of normal range" (pathological blood flow) was considered as above 40 cm/sec. Additional details see [40].…”

Section: A Comparative Population Screening With Cerberus Systemmentioning

confidence: 99%

See 2 more Smart Citations

Studies in Rheoencephalography (REG)

Bodó

2010

Journal of Electrical Bioimpedance

View full text Add to dashboard Cite

This article presents an overview of rheoencephalography (REG) -electrical impedance measurements of the brain -and summarizes past and ongoing research to develop medical applications of REG for neuro-critical care and for primary prevention of stroke and cardiovascular disease. The availability of advanced electronics and computation has opened up the potential for use of REG technology as a noninvasive, continuous and inexpensive brain monitor for military and civilian applications. The clinical background information presented here introduces physiological and clinical environments where REG has potential for use in research and clinical settings.REG studies over the past three decades have involved in vitro and in vivo groups (animal and human), including more than 1500 measurements and related electronic and computational results and practical applications. In vitro studies helped researchers understand the flow/volume relationship between Doppler ultrasound and electrical impedance signals and supported development of REG data processing methods. In animal studies, REG was used to monitor the lower limit of cerebral blood flow (CBF) autoregulation (AR) using a newly developed algorithm. These animal studies also confirmed correlations between REG and measurements of carotid flow (CF) and intracranial pressure (ICP). Human studies confirmed the applicability of REG for detecting cerebrovascular alteration, demonstrating the usefulness of REG in the field of stroke/cardio-vascular disease prevention. In these studies, REG was compared to known stroke risk factors and to results obtained using carotid ultrasound measurements. An intelligent REG system (Cerberus) has been developed for primary stroke prevention. In these studies, the biologically relevant variables of the REG signal were pulse amplitude (minimummaximum distance) and duration of the anacrotic (rising) portion of the REG pulse wave.The principal limitation of REG for clinical application is the lack of pathological and physiological correlations. The studies presented here have initiated such inquiries, but many clinical questions about the pathophysiological background of REG remain unanswered.These results demonstrate that REG development is a multidisciplinary subject with relevance for medicine (vascular neurology and neurosurgery intensive care); electronic engineering; mathematics, and computer science (data processing). It is hoped that information presented in this article will provide assistance to those involved in REG research, particularly in development and clinical applications.

show abstract

Section: Cerberus Measurementsupporting

confidence: 57%

“…The analyzed REG sample involved 457 subjects, 309 female and 148 male. Psychological tests and comparative analysis were part of the full protocol; detailed elsewhere [39,40].…”

Section: A Comparative Population Screening With Cerberus Systemmentioning

confidence: 99%

See 1 more Smart Citation

Studies in Rheoencephalography (REG)

Bodó

2010

Journal of Electrical Bioimpedance

View full text Add to dashboard Cite

show abstract

“…Additionally, anxiety, depression, dementia, neurosis was evaluated (Sipos et al, 2008). Findings: Prevalence of the following stroke risk factors was identified: overweight, 63.25%; sclerotic brain arteries by REG, 54.29%; heart disease, 37.92%; pathologic carotid flow, 34.24%; smoking, 30.55%; high blood cholesterol, 28.70%; hypertension, 27.83%; high triglyceride, 24.35%; abnormality of electrocardiogram, 20%; high glucose level, 15.95%; symptoms of transient ischemic attack, 16.07%; alcohol abuse, 6.74%; and diabetes, 4.53% (Bodo et al, , 1998(Bodo et al, , 2008.…”

Section: Reg -Icp -Cerebral Blood Volume Correlation During Co2 Inhalmentioning

confidence: 99%

“…Cerberus system was created for this purpose. REG measurement is more sensitive at detecting brain arteriosclerotic status than carotid Doppler measurement (Bodo et al, 1998;2008). This suggests that it may be a significantly improved means for the differential diagnosis of neurological disease and the screening of subjects for arteriosclerosis, TIA, and stroke prevention to be offered at the lowest level of medical service.…”

Section: Strokementioning

confidence: 99%

A noninvasive, continuous brain monitoring method: rheoencephalography (REG)

Bodó

2020

DRCSF

View full text Add to dashboard Cite

This paper deals with the sustainability under anoxic conditions of human beings, both when healthy, and diseased. As our attention is focused these days on the environment, sustainability, and green energy, a similar effort is being made in neuromonitoring to switch from invasive to noninvasive monitoring methods. Keys to these changes are computerization and shrinking size of electronic hardware. Computerization is going on in all areas of biomedical engineering, both in research and in clinical fields of medicine. In neurology, brain imaging is the most characteristic change in recent decades. These modalities of imaging (MRI, CT, PET scan, etc.) are predominantly utilized for localizing brain pathology. Brain imaging offers great spatial resolution, but poor time resolution. Therefore, for continuous monitoring, neurocritical care departments require an additional tool with good time resolution. There are invasive and noninvasive neuromonitoring methods. The standard method to monitor intracranial pressure (ICP) is an invasive method. Computerization allows for calculating the cerebral blood flow autoregulation (CBF AR) index (pressure reactivity index - PRx) from ICP and systemic arterial pressure (SAP) in real time, continuously, but invasively. The new development, discussed in this paper, is to calculate this index noninvasively by using rheoencephalography (REG), called REGx. We present the road to this invention and summarize multifold REG related results, such as using REG for primary stroke prevention screening, comparison incidence of arteriosclerotic risk factors, various studies by using CBF manipulations, and correlations with other neuromonitoring methods, and validation with in vitro and in vivo methods. REG by using different algorithms allow for real time calculation of autoregulated blood flow. This paper presents results of validation of CBF algorithms as an effective, noninvasive method. The author’s intent is to supply sufficient physiological background information. This review covers the author’s research efforts over several decades; it pertains multiple studies and has an updated addition to human sustainability by considering that Covid-19 is increasing stroke and cardiovascular disease (CVD) morbidity and mortality.

show abstract

Characteristics of Rheoencephalography and some associated factors on menopausal women

Nguyen

Tran

et al. 2022

Journal of Electrical Bioimpedance

View full text Add to dashboard Cite

The significant drop in estrogen levels during menopause increases the cardiovascular risks, one of which is cerebrovascular atherosclerosis. Research on rheoencephalography (REG) parameters for the early diagnosis of cerebrovascular atherosclerotic lesions is of great interest to scientists because of its ease of implementation, low cost, and non-invasiveness. The objectives of study are to evaluate the vascular tone, cerebral circulation flow in each hemisphere of the brain of menopausal women, and some associated factors through waveform characteristics and parameters in REG. A controlled cross-sectional descriptive study was conducted on a group of patients including 80 menopausal women and a control group of 46 menstruating women. All patients were measured REG in the frontal-occipital leads by VasoScreen 5000 impedance REG meter. In menopausal women, the percentage of sharp waves, the percentage of clear side waves, and the average REG were all lower than in the control group (p<0.01). The mean conduction time and mean slope ratio was lower than the control group (p<0.001). The mean peak time was higher than the control group (p<0.01). The mean elasticity index (alpha/T) was higher than the control group (p<0.001). Menopausal women have increased vascular tone, the highest in the group of women 50-60 years old, menopause <5 years, having a habit of eating red meat; and decreased blood flow intensity, the highest in the group of women <50 years old. However, the difference was statistically significant only in the left hemisphere (p<0.05). Vascular hypertonia in menopausal women with central obesity was higher than in the non-obese group in both hemispheres (p<0.05). In conclusion, menopausal women had atherosclerosis in both hemispheres of the brain, which was clearly shown in the rate of increased vascular tone. Central obesity may increase the risk of vascular hypertonia 3.75 times in the right and 5.44 times in the left hemisphere.

show abstract

Prevalence of stroke/cardiovascular risk factors in Hungary

Cited by 5 publications

References 3 publications

Studies in Rheoencephalography (REG)

Studies in Rheoencephalography (REG)

A noninvasive, continuous brain monitoring method: rheoencephalography (REG)

Characteristics of Rheoencephalography and some associated factors on menopausal women

Contact Info

Product

Resources

About