Prevalence of Some Extended Spectrum beta- Lactamase Producing Enterobacteriaceae in Human: A Retrospective Study

Baqy, Fatma A. Abd El; Rizk, Mohamed; Haggag, Yasser N.; Nossair, Mohammad; Mansour, Alaa; Elaadli, Haitham

doi:10.5455/ajvs.56924

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…These modifications are due to amino acid substations which are reported to have been developed from common ancestors. [33][34] The CTX-M-15 spread in United Kingdom after it was first reported and the isolates were linked to E.coli. [35][36] International travel and immigration added to the speedy appearances and spread of CTX-M enzymes all over the world.…”

Section: Penetration and Globalization Of Ctx-m Enzymes All Over The ...mentioning

confidence: 99%

Drug Resistance due to Elaboration of Beta Lactamases and the Role of CTX-M in Enterobacteriaceae

Sohail¹,

Taj²,

Satti³

et al. 2022

J. Bahria Uni. Med. Dent. Coll.

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The Enterobacteriaceae family are the most common pathogens associated with hospital and community acquired infections worldwide. These bacteria are treated with broad spectrum antibiotics especially 3rd generation cephalosporins. Over the period of time due widespread and rigorous use of these medications, Enterobacteriaceae has developed antibiotic resistance (AMR). Among all, the most compelling antibiotic resistance mechanism is production of -lactamases enzymes by this microorganism. Over the course of time -lactamase has evolved more than 1300 distinct enzymes. Amongst these most deleterious is extended spectrum beta lactamases (ESBL). ESBL producing Enterbacteriacaeae are responsible for a high number of deaths worldwide. These enzymes are considered challenging as they are difficult to be identified in the laboratory wShich cause delay in diagnosis and administration of appropriate antimicrobial therapy. The coexistence of ESBL with other antibiotic resistance gene is another therapeutic challenge rendering empirical antibiotic treatment ineffective

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Section: Penetration and Globalization Of Ctx-m Enzymes All Over The ...mentioning

confidence: 99%

Drug Resistance due to Elaboration of Beta Lactamases and the Role of CTX-M in Enterobacteriaceae

Sohail¹,

Taj²,

Satti³

et al. 2022

J. Bahria Uni. Med. Dent. Coll.

View full text Add to dashboard Cite

show abstract

Prevalence of Some Extended Spectrum beta- Lactamase Producing Enterobacteriaceae in Human: A Retrospective Study

Cited by 1 publication

References 12 publications

Drug Resistance due to Elaboration of Beta Lactamases and the Role of CTX-M in Enterobacteriaceae

Drug Resistance due to Elaboration of Beta Lactamases and the Role of CTX-M in Enterobacteriaceae

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