Prevalence of sleep abnormalities and their association among hypothyroid patients in an Indian population

Krishnan, Prakash; Vadivu, A. Senthil; Alappatt, Ashish; Kameswaran, Mohan

doi:10.1016/j.sleep.2012.07.006

Cited by 10 publications

(3 citation statements)

References 16 publications

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“…One article attributes this connection to low thyroid levels causing muscle/joint pain, cold intolerance, and anxiety, which may instigate increased sleep latency, difficulty sleeping, and excessive daytime sleepiness [ 12 ]. A cross-sectional study conducted among individuals of Indian descent found that daytime sleepiness and snoring had a significant correlation with impaired functioning of thyroid hormones [ 14 ]. Similarly, a retrospective study that evaluated female patients with hypothyroidism found that early chronotype, defined as those with a propensity for early awakenings, had higher TSH levels in the early evening and the middle of the night [ 15 ].…”

Section: Reviewmentioning

confidence: 99%

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Thyroid Function and Sleep Patterns: A Systematic Review

Addanki,

Patel,

Patel

et al. 2024

Cureus

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Hypothyroidism, defined as a low metabolic function of the thyroid gland that results in low thyroid hormone levels, and insomnia, a condition with the inability to sleep, are two distinct conditions with little overlap that have been extensively established. Both conditions have been studied independently in terms of epidemiology, pathophysiology, diagnosis, and management. The exact causal relationship between the two conditions has yet to be elucidated, and a direct underlying pathophysiology has not been pinpointed. To gain further insight into the relationship between hypothyroidism and insomnia, we performed a systematic review to explore this relationship using predetermined guidelines. Out of 59 studies assessed, four studies evaluated the mechanisms of these two potentially comorbid conditions. Our findings suggest that hypothyroidism and insomnia may have a bidirectional relationship, with symptomatic overlap that is tied to increased metabolic comorbidities and hormonal dysregulation. These findings warrant further research to verify these early findings and gain further insight into the relationship between these conditions. A better understanding of the pathophysiology of overlap between these two conditions will help improve diagnosis and target treatment more effectively.

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Section: Reviewmentioning

confidence: 99%

“…This study focused on obese women of South Asian descent who were found to have significantly increased daytime sleepiness and impaired thyroid function. It has been found that hypothyroid patients and obese patients have depression of the respiratory center and altered bellows, affecting their thorax and sleeping patterns [ 14 ].…”

Section: Reviewmentioning

confidence: 99%

Thyroid Function and Sleep Patterns: A Systematic Review

Addanki,

Patel,

Patel

et al. 2024

Cureus

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“…The assessment of regional accumulation of excess adiposity, especially in the upper body segment is considered a better predictor of obesity related complications including hypertension, diabetes, and cardiovascular diseases [1,5]. Recently, some population based studies from India have also tried to establish the relationship of NC with regional adiposity, metabolic disorders, cardiovascular diseases and related co-morbidities among Asian Indian populations [1,27,28].…”

Section: Introductionmentioning

confidence: 99%

Cut-off point estimation of Neck circumference to determine Overweight and Obesity among Asian Indian adults

Mondal

Timungpi

Kathar

et al. 2022

ebph

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Background: Neck circumference (NC) is a relatively new anthropometric measure of differentiating body fat distribution and considered as a marker of upper subcutaneous adiposity. Aims and Objectives: The present study was undertaken to assess the suitability and cut-offs estimation of NC to determine overweight and obesity in Asian Indian adults. Materials and Methods: The present cross-sectional study was carried out among 1830 adults (914 males; 916 females) aged 20-49 years of Karbi-Anglong, Northeast-India, using multistage-stratified sampling method. Height, weight, waist circumference (WC) and neck circumference (NC) were recorded using standard procedures. The body mass index (BMI kg m−2) was calculated and overweight and obesity were assessed using standard cut-offs. Results: Linear and binary logistic regression analyses showed that NC had a better predictive value of BMI (p<0.001). The ROC-AUC results showed that NC seems to have relatively better predictive value in greater adiposity (BMI≥30.00 kg m−2) among both males (AUC 0.83, 95% CI: 0.81-0.86) and females (AUC 0.88, 95%CI: 0.85-0.89) (p<0.01). The cut-offs of NC were observed to be 36.0 cm and 38.0 cm (in males) and 30.9 cm and 33.0 cm (in females) for BMI ≥25.00 kg m−2 and BMI 30 kg m−2, respectively. Conclusion: Further studies should be undertaken to determine and validate the existing and/or newly proposed cut-offs among larger samples for pan-Indian cut-offs for the assessment of overweight and obesity and related risks of non-communicable diseases and metabolic disorders.

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