Prevalence of Skin Cancer in Chronic Arsenicosis in Chittagong Medical College Hospital

Alam, Mansurul; Hazari, Saroj K. S.; Alam, Asm Tawhidul

doi:10.3329/jcmcta.v21i1.7666

Cited by 6 publications

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“…These management measures are found to be helpful in the early recovery of mild and moderate arsenicosis patients. But recovery is difficult in severe arsenicosis cases or in cases with complications 22,43–45. In Bangladesh, several studies have been carried out to assess different treatment regimens for arsenicosis patient management.…”

Section: Introductionmentioning

confidence: 99%

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Arsenic contamination in groundwater in Bangladesh: implications and challenges for healthcare policy

Shojaei¹,

Khan²,

Haque³

2018

RMHP

181

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Arsenic contamination of groundwater in Bangladesh has been recognized as a major public problem. The arsenic contamination was first identified in the tubewell water in 1993 in a northern district of Bangladesh. Tubewells are the main source of drinking water in rural areas, and except hilly and terrace upland throughout the Bangladesh, the arsenic-contaminated tube-wells are distributed. Fifty million people of Bangladesh were estimated to be at risk of exposure to arsenic through consumption of water from contaminated tubewells. Chronic exposure to arsenic causes arsenicosis and may include multi-organ pathologies. Many of the health effects of chronic toxicity are evident in Bangladesh. Besides dermatological manifestations, noncommunicable diseases including cancer, adverse pregnancy outcomes, and decreased intelligence quotient among the children are reported to be increasing. Cancer due to long-term low-dose arsenic exposure through consumption of contaminated water is now an important concern of Bangladesh as it is being increasingly reported from arsenic-exposed individuals. Stoppage of consumption of the arsenic-contaminated water is the mainstay of arsenicosis prevention and case management. At present, a higher proportion of the people are still consuming arsenic-contaminated water because of the lack of sustainable arsenic-safe water supply. In providing sustainable arsenic-safe water options, any option advocated should be cheap, easy to use, locally maintainable, and owned by the community. In addressing arsenic-related health issues, arsenic-exposed population needs to be brought under the coverage of the regular surveillance program for detection and subsequent management of noncommunicable diseases and cancers.

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Section: Introductionmentioning

confidence: 99%

“…Patients treated with spirulina, selenium, or folic acid showed a little improvement. However, vitamin A (β-carotene), E, and C regimen still is a commonly practised management for arsenicosis patients 43–46. DGHS supplies vitamin A, E, C to Upazilla Health Complexes for the management of arsenicosis patients, free of cost.…”

Section: Introductionmentioning

confidence: 99%

Arsenic contamination in groundwater in Bangladesh: implications and challenges for healthcare policy

Shojaei¹,

Khan²,

Haque³

2018

RMHP

181

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“…Recovery or improvement was found to have occurred among those who had followed the advice and instructions properly. It has been reported that recovery and improvement was more likely patients with mild or moderate arsenicosis if they consumed arsenic safe water and took antioxidants regularly; however, recovery in patients with severe disease or complications was time taking or even difficult [2,18,19,20,21,22,23]. Though the antioxidants were found to be useful, the mechanism was not clear.…”

Section: Discussionmentioning

confidence: 99%

Twenty Years of Arsenic Contamination and Arsenicosis Patients in a Village of Bangladesh

Shojaei¹,

Faruquee²,

Khan³

2020

AJPHR

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Background: Arsenic contamination in groundwater of Bangladesh was first detected in 1993 and still a major public health problem in the country. In 1997, Samta was identified as a severely arsenic contaminated village and many villagers were found to suffering from arsenicosis. Methods: A series of surveys were carried out in Samta village in the years 1997, 2002, 2008 and 2017 to assess the situation of arsenic contamination and the status of arsenicosis in the village. The water sources and the entire population of the village were included in the study. Results: In 1997 about 87% of the shallow tubewells in Samta village were arsenic-contaminated and 10.1% villagers had arsenicosis. Twenty years later in 2017, about 90% shallow tubewells were arsenic contaminated, 39 deep tubewells and a pond sand filter were installed in the village and 2.3% of the villagers had arsenicosis. On an average 43.8% arsenicosis patients had recovered from the illness and condition of 21.2% patients had deteriorated or remained unchanged. During the 20-year period 37(6.1%) arsenicosis patients and 185(1.6%) non-arsenicosis villagers had died. The main cause of death among arsenicosis patients was cancer (40.5%) and among non-arsenicosis villagers the cause was geriatric problem (11.8%). The mean age at death was 57.6 years and 61.2 years respectively. Conclusion: In twenty years, measures were undertaken to make available arsenic-safe water options and people were motivated to stop the use of arsenic-contaminated water and to increase the intake of protein and vitamin AEC rich food. Recovery had occurred in a substantial proportion of patients.

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“…However, skin cancers were more common and the types of skin cancers are squamous cell cancer and basal cell cancer. Bowen's disease is a precancerous skin lesion and is evident among the arsenicosis patients of Bangladesh [7,12,74]. It is estimated that there will be a doubling of the potential lifetime mortality risk from cancer in Bangladesh due to arsenic in drinking water and it is indicated that the overall lifetime mortality risk due to cancer of the lung, liver, and bladder resulting from such exposure will be 229.6 per 100,000 population [72].…”

Section: Suspected Case Showing Melanosis or Keratosis After Excludinmentioning

confidence: 99%

“…Mild and moderate arsenicosis cases are found to recover from illnesses using the above management regimen. However, severe arsenicosis cases or cases with complications take longer to recover [1,74,77]. Studies carried out on arsenicosis patient management with different treatment regimens such as spirulina, selenium, and folic acid in Bangladesh found that none of these regimens is very effective [61,77,78], However, the vitamin A, E, and C regimen is still commonly used for arsenicosis management in Bangladesh [74].…”

Section: Management Of Arsenicosis Patients In Bangladeshmentioning

confidence: 99%

Ground Water Arsenic Contamination and Its Health Effects in Bangladesh

Shojaei

Khan

2015

Handbook of Arsenic Toxicology

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Prevalence of Skin Cancer in Chronic Arsenicosis in Chittagong Medical College Hospital

Abstract: Key words: chronic arsenicosis, prevalence; skin cancerDOI: 10.3329/jcmcta.v21i1.7666 Journal of Chittagong Medical College Teachers' Association 2010: 21(1):23-29

Cited by 6 publications

References 0 publications

Arsenic contamination in groundwater in Bangladesh: implications and challenges for healthcare policy

Arsenic contamination in groundwater in Bangladesh: implications and challenges for healthcare policy

Twenty Years of Arsenic Contamination and Arsenicosis Patients in a Village of Bangladesh

Ground Water Arsenic Contamination and Its Health Effects in Bangladesh

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