Prevalence of silent myocardial ischemia in single and multiple lacunar infarcts and large vessel disease stroke

Araúz, Antonio; Calleja, Juan Manuel; Vallejo, Enrique; Quintero, Lisveth

doi:10.1016/j.clineuro.2010.04.019

Cited by 6 publications

(6 citation statements)

References 22 publications

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“…Baumgartner et al (21) reported cigarette smoking in 51%. In contrast with our study, Bessonet al and spolveri obtained significant differences (15,23). TIA history was more frequent in PMS but there were no significant differences between it and the all subgroups of infarcts.…”

Section: Discussioncontrasting

confidence: 55%

“…The mean age of the male patients was 64.4 ±7.7 (they were in range of 41-80) and of the female patients was 63.1± 9.4 y (they were in range of 40-83). Although in most other studies (15), lacunar infarct was more frequent in males, in this study, it was more frequent in females, but there was no significant difference between them. PMS were the most frequent syndrome in this study (53.5%) which resembles the other studies (16).…”

Section: Discussioncontrasting

confidence: 49%

“…But there were no significant differences between triglyceridemia and the other subgroups of infarct. Although we did not find any significant difference between triglyceridemia and PSS and SMS syndromes, hyperlipidemia has been reported as a risk factor for lacunar infarcts in many studies (15) Cigarette smoking was more frequent in PMS. There were 28 (27.7%) patients with smoking history but there were no significant differences between it and the subgroups of infarcts.…”

Section: Discussioncontrasting

confidence: 44%

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Magnetic Resonance Imaging (MRI) findings in patients with brain small vessel disease

Forughipur

Pourrashidi-Boshrabadi

Tafakhori

et al. 2017

IMMINV

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Background: Cerebral small vessel disease (SVD) affects small perforating arteries, causing both lacunar infarction (LI) and confluent white matter lesions (WML). Small vessel disease or lacunar infarct is one of the major stroke subgroups. Lacunar syndromes may be divided into two groups: the classic group (pure motor hemiplegia, pure sensory stroke, ataxic hemiparesis, dysarthria-clumsy hand syndrome, sensorimotor stroke) and the miscellaneous group, including all other lacunar syndromes. We have evaluated risk factors, clinical syndromes, topography, and laboratory findings of 101 consecutive patients with symptomatic lacunar infarcts diagnosed by magnetic resonance imaging. Methods: We analyzed 101 patients with clinical lacunar infarct syndrome who were referred to the neurology department of Qa'em hospital, Mashhad in the northeast of Iran. We assessed clinical features, sex, age, risk factors, radiologic findings and laboratory data of these patients. Results: The pure motor hemiparesis (53.5%) constituted the most usual lacunar syndrome. Mean age of the patients was 63.7± 8.5%. Diabetes mellitus was seen in 14 (13.9%) and hypercholesterolemia in 41 (40.6%) of patients. There were significant differences among ataxic-hemiparesis syndrome and hypertriglyceridemia and CVA history. There was a significant difference between miscellaneous syndromes and valve disease history. Also, there was significant correlation between WML and smoking. Thirty percent of the lesions were detected by CT scan. Conclusion: Sixty percent of the cases were associated with white matter signal changes. Diabetes mellitus were found in 14% of patients. Hypertriglyceridemia, CVA history and valve disease history were associated with some subgroups, but more investigations should be performed for precise assessment of other risk factors.

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Section: Discussioncontrasting

confidence: 55%

Section: Discussioncontrasting

confidence: 49%

Section: Discussioncontrasting

confidence: 44%

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Magnetic Resonance Imaging (MRI) findings in patients with brain small vessel disease

Forughipur

Pourrashidi-Boshrabadi

Tafakhori

et al. 2017

IMMINV

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“…With the exception of a single autopsy study 23 where the median time between stroke and death was 12 days (IQR 5–32 days), all studies recruited patients with stroke within 10 days. While most studies included ischaemic stroke of atherosclerotic aetiology, three studies excluded cardioembolic stroke 5 10 32 and only one study included those with suspected cardioembolism. 29 Three studies looked exclusively at first ischaemic stroke.…”

Section: Resultsmentioning

confidence: 99%

Quantifying the risk of heart disease following acute ischaemic stroke: a meta-analysis of over 50 000 participants

et al. 2016

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ObjectiveFollowing an acute stroke, there is a high risk of recurrence. However, the leading cause of mortality following a stroke is due to coronary artery disease (CAD) and myocardial infarction (MI) but that risk has not been robustly quantified. We sought to reliably quantify the risk of ischaemic heart disease (IHD) in patients presenting with acute ischaemic stroke (AIS) in the absence of a known cardiac history.SettingA meta-analysis study. PubMed, MEDLINE, EMBASE and Google Scholar were searched for potential studies up to October 2015. Included studies reported an acute cerebral ischaemic event and followed for CAD or MI within 1 year in patients without known IHD. Using arcsine transformed proportions for meta-analysis, studies were combined using a generic inverse variance random-effects model to calculate the pooled standardised mean difference and 95% CIs. These were interpreted as the percentage prevalence of CAD or incidence of MI following AIS.Results17 studies with 4869 patients with AIS demonstrated a mean average of asymptomatic CAD in 52%. Anatomical methods of CAD detection revealed a prevalence of asymptomatic ≥50% coronary stenosis in 32% (95% CI 19% to 47%; p<0.00001). 8 studies with 47229 patients with ischaemic stroke revealed an overall risk of MI in the year following stroke of 3% (95% CI 1% to 5%; p<0.00001) despite the absence of any cardiac history.ConclusionsOne-third of patients with ischaemic stroke with no cardiac history have more than 50% coronary stenosis and 3% are at risk of developing MI within a year. Our findings provide a reliable quantitative measure of the risk of IHD following AIS in patients with no cardiac history.

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“…Механизмы возникновения ББИМ не отличаются от механизмов развития стенокардии напряжения [2][3][4]. В основе ББИМ лежит несоответствие между потребностью миокарда в кислороде и доставкой кислорода к миокарду.…”

Section: ишемическая болезнь сердца §unclassified

Silent Myocardial Ischemia as a Result of Cardiac Autonomic Neuropathy

2019

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Aim: to verify the effect of vegetative nervous system on the silent myocardial ischemia.Materials and methods. We included in this study 56 patients with functional class II–III effort angina (22 men and 34 women, age 45–49 years) with silent myocardial ischemia (SMI). Examination included 24hour blood pressure and ECG monitoring.Results. We revealed the interrelation between elevation of parameters of heart rhythm variability reflecting activity of parasympathetic nervous system and ST segment depression depth during episodes of SMI. Also, а significant interrelationship was found between SMI duration and degree of nocturnal diastolic blood pressure decrease which reflected parasympathetic nervous system activity.Conclusion. Silent myocardial ischemia more often occurred at the background of elevated activation of the parasympathetic nervous system.

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Prevalence of silent myocardial ischemia in single and multiple lacunar infarcts and large vessel disease stroke

Cited by 6 publications

References 22 publications

Magnetic Resonance Imaging (MRI) findings in patients with brain small vessel disease

Magnetic Resonance Imaging (MRI) findings in patients with brain small vessel disease

Quantifying the risk of heart disease following acute ischaemic stroke: a meta-analysis of over 50 000 participants

Silent Myocardial Ischemia as a Result of Cardiac Autonomic Neuropathy

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