Prevalence of sensitization to weed pollens of Humulus scandens, Artemisia vulgaris, and Ambrosia artemisiifolia in northern China

Hao, Guodong; Zheng, Yiwu; Gjesing, Birgitte; Kong, Xing-ai; Wang, Jing‐Yuan; Song, Zhi-jing; Lai, Xuxin; Zhong, Nanshan; Spangfort, Michael D.

doi:10.1631/jzus.b1200185

Cited by 30 publications

(18 citation statements)

References 18 publications

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“…There was a markedly higher frequency of specific IgE to Artemisia (58.3%) correlating to Art v 1 reactivity (49%). In contrast, specific IgE to Ambrosia (14.7%) and Amb a 1 (11.2%) was lower in frequency and level, not correlated with each other, and uncommon in the absence of specific IgE to Art v 1 suggesting primary sensitization with Artemisia species . Epidemiological studies on pollen‐allergic patients performed in Spain identified a frequency of sensitization to Art v 1 of 13% .…”

Section: Sensitization To Individual Molecules and Their Clinical Relmentioning

confidence: 89%

EAACI Molecular Allergology User's Guide

Matricardi

Kleine-Tebbe²,

Hoffmann

et al. 2016

Pediatric Allergy Immunology

724

870

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The availability of allergen molecules ('components') from several protein families has advanced our understanding of immunoglobulin E (IgE)-mediated responses and enabled 'component-resolved diagnosis' (CRD). The European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User's Guide (MAUG) provides comprehensive information on important allergens and describes the diagnostic options using CRD. Part A of the EAACI MAUG introduces allergen molecules, families, composition of extracts, databases, and diagnostic IgE, skin, and basophil tests. Singleplex and multiplex IgE assays with components improve both sensitivity for low-abundance allergens and analytical specificity; IgE to individual allergens can yield information on clinical risks and distinguish cross-reactivity from true primary sensitization. Part B discusses the clinical and molecular aspects of IgE-mediated allergies to foods (including nuts, seeds, legumes, fruits, vegetables, cereal grains, milk, egg, meat, fish, and shellfish), inhalants (pollen, mold spores, mites, and animal dander), and Hymenoptera venom. Diagnostic algorithms and short case histories provide useful information for the clinical workup of allergic individuals targeted for CRD. Part C covers protein families containing ubiquitous, highly cross-reactive panallergens from plant (lipid transfer proteins, polcalcins, PR-10, profilins) and animal sources (lipocalins, parvalbumins, serum albumins, tropomyosins) and explains their diagnostic and clinical utility. Part D lists 100 important allergen molecules. In conclusion, IgE-mediated reactions and allergic diseases, including allergic rhinoconjunctivitis, asthma, food reactions, and insect sting reactions, are discussed from a novel molecular perspective. The EAACI MAUG documents the rapid progression of molecular allergology from basic research to its integration into clinical practice, a quantum leap in the management of allergic patients.

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Section: Sensitization To Individual Molecules and Their Clinical Relmentioning

confidence: 89%

EAACI Molecular Allergology User's Guide

Matricardi

Kleine-Tebbe²,

Hoffmann

et al. 2016

Pediatric Allergy Immunology

724

870

View full text Add to dashboard Cite

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“…A total of 1,144 subjects (aged from 5 to 68) from June to October 2011 underwent intradermal testing using a panel of 25 allergen sources [ 65 ]. Of the 1,144 subjects, 170 had positive intradermal reactions to pollen and 144 donated serum for IgE testing from these 170 subjects.…”

Section: Epidemiology Of Artemisia Allergymentioning

confidence: 99%

ArtemisiaAllergy Research in China

Tang

Yin

et al. 2015

BioMed Research International

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Artemisia is the most important outdoor allergen throughout China. It can cause allergic rhinitis, asthma, or both of them. Since it was verified as an allergenic pollen in 1960, it was identified two times in the Chinese National Pollen Survey (1984, 2009). The first oral immunotherapy double-blinded trial for Artemisia pollen asthma research was conducted in China in 1989 and published in 1990. 40 years since that study, there have been many published research reports on Chinese Artemisia allergy. This review summarizes the information regarding the discovery of Artemisia as an allergenic pollen, pollen account, epidemiology, allergen components, immunological changes in hay fever patients, natural course from rhinitis to asthma, diagnosis, and immunotherapies in China.

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“…Component‐resolved diagnosis (CRD) enables IgE sensitization profiles and potential risk to be established, and whether specific IgE is the result of primary sensitization or cross‐reactivity can also be determined . Such information can assist in making the right choice of immunotherapy, particularly when pollen seasons of different allergenic sources overlap . Seven Artemisia pollen allergens have been identified and listed in the IUIS database (http://www.allergen.org), including the recently added 62 kDa putative galactose oxidase protein (Art an 7), first purified from sweet wormwood ( A. annua ) .…”

Section: Introductionmentioning

confidence: 99%