Prevalence of sensitive skin and its biophysical response in a Mexican population

Relationship between transient receptor potential vanilloid‐1 expression and the intensity of sensitive skin symptoms

“…Therefore, the group with an upregulated TRPV1 may expose an accelerated response that translates into a lower clinical sensitivity threshold to LAST. Also, sensitive skin has been related to a disruption in the barrier function of the skin, and separately, TRPV1 expression has been correlated to a poorer response of the barrier function . Thus, our findings are in agreement with these reports, supporting an association between sensitive skin and TRPV1 expression.…”

“…An impaired barrier function has been demonstrated in previous studies, mostly due to an increased TEWL . Therefore, a thinner or impaired stratum corneum can favor a higher transcutaneous penetration of water‐soluble chemicals, which makes the subject more susceptible to exogenous factors .…”

“…Negative volunteers to LAST were considered as controls. Values were interpreted as 0 if no discomfort, 1–4 meant an increasing but tolerable discomfort, 5–9 meant an increasing and intolerable discomfort, and 10 meant the worst discomfort ever experienced …”

“…Differences in the prevalence have been related to sex, age, and cultural factors . Recently, we observed that skin phototype could also influence the presence of sensitive skin by finding a higher prevalence of positive LAST in lighter subjects (i.e., II–III phototypes), compared to darker ones (i.e., IV–V) …”

Gender‐related characterization of sensitive skin in normal young Chinese

“…The principal characteristics of sensitive skin have been assessed in general population. Previous studies showed that the prevalence of sensitive skin varies greatly with country . Ethnic variation in the prevalence of self‐perceived sensitive skin was also identified in the 45‐ to 54‐year‐old group .…”