Prevalence of Scrub typhus among Patients attending a Tertiary Care Hospital - A Prospective and Retrospective study
Priyadarshini Shanmugam
Abstract:Background: Scrub typhus is an emerging acute febrile illness caused by a gram-negative obligate intracellular bacterium, Orientia tsutsugamushi. It is transmitted by a chigger mite that acts as a vector. This study was carried out to understand the prevalence, clinico-haematological profile and clinical outcome of patients who tested positive for scrub typhus (ST).
Materials and Methods:This study, both retrospective and prospective, was conducted in the Department of Microbiology, Chettinad Hospital and Rese… Show more
Objective: Re-emergent cases of rickettsial disease, the scrub typhus is seen prevalent in cases of acute febrile illness. The objective of this study was to study the magnitude and prevalence of scrub typhus in a tertiary care hospital.
Methods: This prospective study was carried on for a period of one year from February 2023 to February 2024. Inpatients between the age group of 16 to 25 y with a triad of fever for more than 5 d of onset with or without an eschar, headache, myalgia and abnormal haematological and biochemical parameters were included in the study. IgM ELISA for scrub typhus was performed.
Results: Prevalence of scrub typhus in this study was 9.4% with higher male preponderance of 69.4% in 18 y age group 28.6%. Positive cases were recorded higher during post monsoon season of September 18.9%. Co-infection with dengue and malaria observed in 2 cases and ARDS was the complication in 3 cases. No mortality in this study.
Conclusion: It is important to get familiar with the clinical and diagnostic laboratory findings of scrub typhus so as to differentiate it from other aetiologies of acute febrile illness.
Objective: Re-emergent cases of rickettsial disease, the scrub typhus is seen prevalent in cases of acute febrile illness. The objective of this study was to study the magnitude and prevalence of scrub typhus in a tertiary care hospital.
Methods: This prospective study was carried on for a period of one year from February 2023 to February 2024. Inpatients between the age group of 16 to 25 y with a triad of fever for more than 5 d of onset with or without an eschar, headache, myalgia and abnormal haematological and biochemical parameters were included in the study. IgM ELISA for scrub typhus was performed.
Results: Prevalence of scrub typhus in this study was 9.4% with higher male preponderance of 69.4% in 18 y age group 28.6%. Positive cases were recorded higher during post monsoon season of September 18.9%. Co-infection with dengue and malaria observed in 2 cases and ARDS was the complication in 3 cases. No mortality in this study.
Conclusion: It is important to get familiar with the clinical and diagnostic laboratory findings of scrub typhus so as to differentiate it from other aetiologies of acute febrile illness.
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