Prevalence of schistosomiasis mansoni in indigenous Maxakali villages, Minas Gerais, Brazil

Nacife, Maria Beatriz Pena e Silva Leite; Siqueira, Liliane Maria Vidal; Martins, Rafael; Vianna, Valeska Natiely; Barbosa, Keila Furbino; Masioli, Cássio Zumerle; Silva, Jaime Costa da; Machado-Coelho, George Luiz Lins

doi:10.1590/s1678-9946201860026

Cited by 9 publications

(12 citation statements)

References 19 publications

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“…A few previous studies have reported the frequency of schistosomiasis in other indigenous peoples in Brazil, all in Minas Gerais. The rate of positivity for schistosomiasis among the Maxakali people was reported to be 23.7% in 2009 (18) and 51.9% in 2013 (19) ; among the Pataxó people, it was reported to be 5.0% in 2012 (20) . No liver or spleen involvement was reported in any of those studies.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound evaluation of schistosomiasis-related morbidity among the Xakriabá people in the state of Minas Gerais, Brazil

et al. 2020

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Objective: To use ultrasound to investigate the morbidity related to schistosomiasis in the Xakriabá indigenous population. Materials and Methods: This was a field-based census study conducted in the territory of the Xakriabá people. A total of 166 individuals were invited, and 148 (≤ 77 years of age) agreed to participate. Most participants underwent abdominal ultrasound, physical examination, and stool examination. Mann-Whitney U and chi-square tests were used for comparisons. We determined risk by calculating odds ratio (OR) and performed logistic regression analysis. Results: Schistosoma mansoni eggs were found in 31 (26.7%) of the 116 stool samples examined, 22 (70.9%) of the 31 being from individuals 4-16 years of age. The median count was 144 eggs/g of feces (interquartile range, 264). Of the 105 participants examined with ultrasound, 68 (64.8%) had hepatomegaly (left lobe), 6 (5.7%) had splenomegaly, and 4 (3.8%) had portal hypertension. Egg-positive stool samples were more common in those with an enlarged left lobe (OR = 3.4; 95% confidence interval (CI): 1.1-11.2; p = 0.043). Periportal fibrosis was found in 30 participants (28.6%), of whom 9 (30%) had pattern C, 10 (33.3%) had pattern D, and 11 (36.7%) had pattern Dc. Age was the only independent risk factor for fibrosis (p = 0.007). Fibrosis was up to nine-fold more common in alcohol drinkers than in nondrinkers (OR = 9.28; 95% CI: 2.60-33.06; p < 0.001). Among the 138 participants in whom the clinical form was classified, the chronic hepatic form was identified in 54 (39.1%), of whom 32 (59.2%) were under 30 years of age and one (1.8%) was hepatosplenic. Conclusion: Schistosomiasis in the Xakriabá population is characterized by a high frequency of egg-positive stool samples, predominantly in children/adolescents, and by chronic hepatic form in the young, especially among alcohol drinkers.

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Section: Discussionmentioning

confidence: 99%

Ultrasound evaluation of schistosomiasis-related morbidity among the Xakriabá people in the state of Minas Gerais, Brazil

et al. 2020

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“…These findings suggest that the disease persists in territories with greater social vulnerability, where poor sanitary conditions and lack of guidance directly influence the health of this population. 24 The study presented limitations such as the impossibility of collecting data in one of the laboratories in the city and the operational difficulty encountered by laboratory E when counting the daily data of the tests performed.…”

Section: Methodsmentioning

confidence: 99%

Persistência e subnotificação da esquistossomose mansônica em município da Zona da Mata de Minas Gerais

Feitosa¹,

Meireles²,

Lara³

2022

Rev Epidemiol Control Infect

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Justificativa e Objetivos: A esquistossomose mansônica é uma doença crônica negligenciadacuja causa é o Schistosoma mansoni, sendo endêmica no Brasil. Apresenta acometimentosistêmico e tem como manifestações clínicas desde dermatites até síndromes clínicas graves commanifestações neurológicas e/ou hepáticas, como cirrose hepática. Apesar de a incidência haverdiminuído na última década, estima-se que haja subnotificação no país. Esta pesquisa teve comoobjetivo verificar a existência de subnotificação e a persistência do caráter endêmico daesquistossomose em um município no interior estado de Minas Gerais (MG) em 2016. Métodos:Trata-se de estudo transversal descritivo com base em dados secundários relativos a resultadospositivos de exames parasitológicos e sorológicos para esquistossomose em residentes domunicípio em sete dos oito laboratórios de análises clínicas existentes. Resultados: Dos 29.266exames avaliados por todas as técnicas, 80 foram positivos, dos quais 50 casos foramconfirmados, com prevalência estimada em 0,17% (IC95% 0,13-0,23%). Nesse ano, foramnotificados também 31 casos de esquistossomose no SINAN-MG. Conclusão: Aesquistossomose em Ponte Nova, MG, persiste com padrão epidemiológico de endemicidade esituação operacional de vigilância de subnotificação. Ressalta-se a importância de fortalecerações de vigilância e de controle para a doença, incluindo a monitorização das áreas endêmicaspara o vetor e o tratamento precoce dos pacientes com PSE positivo.

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“…A new study carried out by Nacife et al showed less positivity for the TF-Test technique in the detection of S. mansoni, and higher positivity for other helminths and protozoa than the Kato-Katz technique. In this study, however, only one fecal sample from each individual was analyzed for logistical reasons, rather than three as in the protocol 101 .…”

Section: Alternative Techniquesmentioning

confidence: 99%

A historical review of the techniques of recovery of parasites for their detection in human stools

Soares

Benitez

Santos

et al. 2020

Rev. Soc. Bras. Med. Trop.

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Since the early 20 th century, the detection of intestinal parasites has improved with the development of several techniques for parasitic structures recovery and identification, which differ in sensitivity, specificity, practicality, cost, and infrastructure demand. This study aims to review, in chronological order, the stool examination techniques and discuss their advantages, limitations, and perspectives, and to provide professionals and specialists in this field with data that lays a foundation for critical analysis on the use of such procedures. The concentration procedures that constitute the main techniques applied in routine research and in parasitological kits are a) spontaneous sedimentation; b) centrifugation-sedimentation with formalin-ethyl acetate; and c) flotation with zinc sulfate solution. While selecting a technique, one should consider the purpose of its application and the technical-operational, biological, and physicochemical factors inherent in the procedures used in stool processing, which may restrict its use. These intrinsic limitations may have undergone procedural changes driven by scientific and technological development and by development of alternative methods, which now contribute to the improvement of diagnostic accuracy.

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Prevalence of schistosomiasis mansoni in indigenous Maxakali villages, Minas Gerais, Brazil

Cited by 9 publications

References 19 publications

Ultrasound evaluation of schistosomiasis-related morbidity among the Xakriabá people in the state of Minas Gerais, Brazil

Ultrasound evaluation of schistosomiasis-related morbidity among the Xakriabá people in the state of Minas Gerais, Brazil

Persistência e subnotificação da esquistossomose mansônica em município da Zona da Mata de Minas Gerais

A historical review of the techniques of recovery of parasites for their detection in human stools

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