Prevalence of rotavirus among children under five years of age with diarrhea in Kaduna State, Nigeria

Abstract

Rotavirus (RV) is a major etiological agent of acute infantile gastroenteritis and is associated with 20%-25% of diarrhea cases in infants. Nigeria continues to be among the first five countries with greatest number of RV disease associated deaths per year. The objective was to determine some demographic factors that might be associated with rotavirus diarrhea among children in Kaduna State. From September 2013-August 2014, 401 diarrheic stool samples were collected from children under 5 years of age in Kaduna State, Nigeria and analyzed for RV antigen using ELISA. An overall RV prevalence of 32.2% (129/401) was obtained with the infection occurring throughout the study period. The infection was higher in males (33.0%:63/111) compared to females (31.4%:66/210). The highest burden was detected in children 25-36 months of age (37.3%:22/59). Highest prevalence was detected in children whose parents had primary education (35.8%:19/53) and those whose parents were civil servants (35.6%:36/101). There was no statistically significant association between breast feeding and RV infection (P> 0.05). The study has revealed that rotavirus remains an important cause of acute diarrhea in children under five years in Kaduna State, Nigeria. Hence the need to introduce the vaccines into the childhood immunization program in the country

Epidemiological Survey of Rotaviruses Responsible for Infantile Diarrhea by the Immunomolecular Technique in Cotonou (Benin, West Africa)

“…Numerous studies have shown the important role of rotaviruses as a cause of diarrhea in children in developed and developing countries, most of which have occurred in children under 5 years of age [ 16 , 17 ]. This prevalence is similar to that in [ 18 , 19 , 20 , 21 ], Kenya [ 22 ], and Jordan [ 23 ] in children of the same age. It is higher than that found in Gabon [ 24 ] and Angola [ 25 ].…”

Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights

“…A study conducted among children in Ibadan in 2016 reported a prevalence of 18.5% [ 38 ]. The most recent report from Northern Nigeria recorded a prevalence rate of 32.2% of rotavirus induced gastroenteritis among children in Kaduna [ 39 ].…”

Prevalence and Molecular Detection of Rotavirus in Children in Ramadi City-Iraq

“…Infected children may also have a cough and runny nose. 8,9,10,11,12,13 Generally, reinfections are common in Rotavirus disease. 14 Immunity develops with each infection, so subsequent infections are less severe; adults are rarely affected.…”