Prevalence of retinopathy of prematurity in Latin America

Carrion, Juliana Zimmermann; Filho, João Borges Fortes; Tartarella, Márcia Beatriz; Zin, Andréa; Jornada, Ignozy Dorneles

doi:10.2147/opth.s25166

Cited by 19 publications

(13 citation statements)

References 24 publications

(22 reference statements)

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“…Blencowe et al [ 6 ] estimated that every year 32,000 neonates became blind or developed severe visual impairment due to ROP worldwide, of which 10% were born in Latin American and the Caribbean. The risk factors associated with ROP were found to vary depending on the region [ 7 ]. These variations are possibly related to the heterogeneity of the population and discrepancy in neonatal care.…”

Section: Introductionmentioning

confidence: 99%

Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study

et al. 2018

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Background and objectivesAdvances in neonatal care promoted increased survival rates of preterm infants, with a consequent increase in the number of children affected by retinopathy of prematurity (ROP). This study estimates the incidence of ROP and evaluates potential risk factors associated.MethodsA retrospective cohort study of preterm infants born in a tertiary neonatal intensive care unit was conducted from March 2005 to August 2015. Six hundred and thirty-nine newborns were included based on the following criteria: infants born with less than 32 weeks’ gestation or birth weight below 1500 g; or neonates born with 32–37 weeks’ gestation or birth weight above 1500 g and any of the following associated: multiple gestation, respiratory distress syndrome, sepsis, blood transfusions or intraventricular hemorrhage. Neonates were followed up until disease resolution or until treatment criteria was achieved.ResultsA total of 602 newborns were evaluated after applying the exclusion criteria. Mean gestational age was 30.7 ± 2.5 weeks. The incidences of ROP at any stage and of type 1 prethreshold ROP were 33.9 and 5.0% respectively. Logistic regression analysis revealed that risk factors associated with ROP at any stage were extremely low birth weight (ELBW) (odds ratio [OR] = 3.10; 95% confidence interval [95% CI]:1.73–5.55), pulmonary diseases (OR = 2.49; 95% CI: 1.35–4.59), intraventricular hemorrhage (OR = 2.17; 95% CI: 1.10–4.30), and low gestational age (OR = 0.81; 95% CI: 0.73–0.91). The main risk factors associated with type 1 prethreshold ROP were pulmonary diseases (OR = 9.58; 95% CI: 1.27–72.04) and ELBW (OR = 3.66; 95% CI: 1.67–8.00).ConclusionThis study found a significant incidence of ROP (33.9%) in the studied population, and highlighted pulmonary diseases as a significant risk factor for type 1 prethreshold ROP.

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Section: Introductionmentioning

confidence: 99%

Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study

et al. 2018

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“…The prevalence of retinopathy in newborn infants in the region ranges from 20 to 30% in those with a birth weight <1500 g, meaning that 1 in every 3 very low birth weight infants has a risk of retinopathy. This aspect is important to address in the quality of care 10 , as the prevalence of blindness due to prematurity retinopathy ranges from 13% to 60% in the region 11 .…”

Section: Introductionmentioning

confidence: 99%

Neonatal Near Miss: the need for a standard definition and appropriate criteria and the rationale for a prospective surveillance system

Santos¹,

Cecatti²,

Serruya³

et al. 2015

Clinics

101

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In Latin American, there is currently a regional action with the main purposes of putting the concept of severe neonatal morbidity in practice and formulating proposals for interventions. A general overview of neonatal health conditions, including morbidity and mortality, is provided to update regional knowledge on the topic. An example of the development and implementation of the concept of maternal near miss is also provided, followed by results from a systematic review covering all previously published studies on Neonatal Near Miss. Finally, some proposals for building a common concept on the topic and for launching a prospective surveillance study are presented. A Neonatal Near Miss is a neonate who had a severe morbidity (organ dysfunction or failure) but who survived this condition within the first 27 days of life. The pragmatic criteria recommended to be used are as follows: birth weight below 1700 g, Apgar score below 7 at 5 minutes of life and gestational age below 33 weeks. As a proxy for organ dysfunction, the following management criteria are also confirmed: parenteral therapeutic antibiotics; nasal continuous positive airway pressure; any intubation during the first 27 days of life; phototherapy within the first 24 h of life; cardiopulmonary resuscitation; the use of vasoactive drugs, anticonvulsants, surfactants, blood products and steroids for refractory hypoglycemia and any surgical procedure. Although this study starts from a regional perspective, this topic is clearly globally relevant. All nations, especially low and middle-income countries, could benefit from the proposed standardization.

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“…For example, Gilbert et al show that if the United Kingdom 2008 screening criteria were applied, an overall of 13% of newborns in middles- and low-income countries would not be examined (< 32 weeks or < 1500 g) [12]. Zimmermann et al presented the prevalence of ROP in Latin America throughout 2000–2010, ranging from 6.6 to 82% at any stage and of severe ROP from 1.2 to 25% based on AAO/AAP guidelines [13]. Also in Freitas et al, recently reported that in a series of 10 years only reported 8/602 patients with > 32 weeks or > 1500 g [14].…”

Section: Discussionmentioning

confidence: 99%

Retinopathy of prematurity: incidence report of outliers based on international screening guidelines

et al. 2019

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AimThe objective of this study is to report the incidence of retinopathy of prematurity (ROP) outliers that fall outside the screening guidelines of the American Academy of Ophthalmology (AAO) in our country.MethodsA retrospective review of 503 records of newborns evaluated in our institution between January 2011 and March 2017. We analyzed the data by subgroups based on gestational age (GA), birth weight (BW) and stage, focusing on the outliers that don’t meet the criteria of the screening AAO guidelines (GA ≤ 30 weeks, BW ≤ 1500 g).ResultsOf the 503 records, 352 had some degree of ROP, 91.76% being bilateral, and 26.2% require treatment. The mean GA at delivery was 30.56 ± 2.33 weeks, and the mean BW was 1287.90 ± 338.52 g. For the current AAO/AAP ROP screening, 19.9% were outliers, of which (57%) had ROP diagnosis and (38%) required treatment.ConclusionsROP diagnosis in newborns of BW > 1500 g or GA > 30 weeks is not uncommon in Mexico, and it is important to take this into account to adjust the selection criteria on each population to reach all the infants at risk.

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Prevalence of retinopathy of prematurity in Latin America

Cited by 19 publications

References 24 publications

Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study

Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study

Neonatal Near Miss: the need for a standard definition and appropriate criteria and the rationale for a prospective surveillance system

Retinopathy of prematurity: incidence report of outliers based on international screening guidelines

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