Prevalence of pulmonary embolism in patients with COVID-19 at the time of hospital admission

Abstract

A high prevalence of venous thromboembolism (VTE) has been reported during Intensive Care Unit (ICU) hospitalisation in patients with severe coronavirus disease (COVID-19) [1, 2]. In most cases, the diagnosis of pulmonary embolism (PE) was incidental as patients underwent computed tomography pulmonary angiography (CTPA) for aggravation of their respiratory condition. Higher mortality is also described in patients with high D-Dimer levels suggesting that VTE complication may contribute to unfavourable prognosis [3, 4]. Even though, prevalence of thromboembolic complications during ICU hospitalisation seems to be high, the prevalence of PE at hospital admission for COVID-19 is unknown and may be underestimated.

Widespread Parenchymal Abnormalities and Pulmonary Embolism on Contrast-Enhanced CT Predict Disease Severity and Mortality in Hospitalized COVID-19 Patients

“…In the Netherlands, thromboembolic complications were reported in 57 of 184 (31%) patients with COVID-19 ARDS and treated in ICU, and the lung was the most common localization of thromboembolism (25%) (5). In a French study, in which all consecutive patients with COVID-19 performed CTPA at admission, PE was diagnosed in 14.2% of the patients (14). Our cohort had a higher frequency of PE than another study that also reported a lower incidence of ICU admissions, suggesting that fewer patients were critically ill (15).…”

Risk factors for pulmonary embolism in patients with COVID-19: a systemic review and meta-analysis

“… Ackermann et al, 2020 , Bunce et al, 2011 , Ceriani et al, 2010 , Chen et al, 2020 , Chi et al, 2020 , Choi et al, 2020 , Connors and Levy, 2020 , Egger et al, 2011 , Fauvel et al, 2020 , Alonso-Fernández et al, 2020 , Flumignan et al, 2020 , Fox et al, 2020 , Gervaise et al, 2020 , Gupta and Madhavan, 2020 , Hajra et al, 2020 , Jalaber et al, 2020 , Jevnikar et al, 2020 , Jiménez et al, 2020 , Higgins et al, 2003 , Ameri et al, 2020 , Huisman et al, 2018 , Kim et al, 2007 , Kirsch et al, 2020 , Konstantinides et al, 2019 , Kosior et al, 2020 , Kunutsor and Laukkanen, 2020 , Lax et al, 2020 , Liao et al, 2020 , Llitjos et al, 2020 , Artifoni et al, 2020 , Mestre-Gómez et al, 2020 , Mouhat et al, 2020 , Mueller-Peltzer et al, 2020 , Nopp et al, 2020 , Ooi et al, 2020 , Pandey and Agarwal, 2020 , Planquette et al, 2021 , Rodriguez-Sevilla et al, 2020 , Poyiadji et al, 2020 , Salje et al, 2020 , Bavaro et al, 2020 , ShiL et al, 2020 , Soumagne et al, 2020 , Soumagne et al, 2020 , Sungnak et al, 2020 , van Dam et al, 2020 , Varga et al, 2020 , Ventura-Diaz et al, 2020 , Watchmaker et al, 2020 , Worldometer COVID-19 Data 2020 , Wu et al, 2020 , Zeng et al, 2015 , Zheng et al, 2020 , Bilaloglu et al, 2020 , BujaL et al, 2020…”

Prevalence of pulmonary embolism on hospital admission in COVID-19 patients: is there a role for pre-test probability scores and home treatment?

“…We read with interest the research letter recently published by Jevnikar et al about the prevalence of pulmonary embolism (PE) in patients with coronavirus disease (COVID-19) at the time of hospital admission [1]. In this prospective multicenter study, all consecutive adult outpatients that were hospitalised with a diagnosis of COVID-19 in three tertiary French hospitals between April 15 th and May 23 rd 2020 underwent computed tomography pulmonary angiography (CTPA).…”