Prevalence of psychiatric morbidity in a difficult asthma population: Relationship to asthma outcome

Heaney, Liam G.; Conway, Eunice; Kelly, Chris; Gamble, J.

doi:10.1016/j.rmed.2005.02.013

Cited by 90 publications

(80 citation statements)

References 24 publications

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“…These are also common in both children and their parents, and maternal depression and poor coping skills may be associated with reduced asthma-related quality of life [150]. Often these conditions are underdiagnosed, so appropriate psychiatric evaluation and referral to a specialist is recommended [151]. Some assessment of family psychosocial stress using standardised questionnaires or direct interviews can be helpful.…”

Section: Remarksmentioning

confidence: 99%

“…Some assessment of family psychosocial stress using standardised questionnaires or direct interviews can be helpful. Unfortunately, the benefit of psychiatric treatment on asthma outcomes has not been wellestablished [151] and a recent Cochrane meta-analysis evaluating psychological interventions involving various relaxation and behavioural techniques both in adults and children was not able to find firm benefit of these interventions on asthma outcomes [152].…”

Section: Remarksmentioning

confidence: 99%

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International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

et al. 2013

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Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A Task Force, supported by the European Respiratory Society and American Thoracic Society, reviewed the definition and provided recommendations and guidelines on the evaluation and treatment of severe asthma in children and adults.A literature review was performed, followed by discussion by an expert committee according to the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach for development of specific clinical recommendations.When the diagnosis of asthma is confirmed and comorbidities addressed, severe asthma is defined as asthma that requires treatment with high dose inhaled corticosteroids plus a second controller and/or systemic corticosteroids to prevent it from becoming “uncontrolled” or that remains “uncontrolled” despite this therapy. Severe asthma is a heterogeneous condition consisting of phenotypes such as eosinophilic asthma. Specific recommendations on the use of sputum eosinophil count and exhaled nitric oxide to guide therapy, as well as treatment with anti-IgE antibody, methotrexate, macrolide antibiotics, antifungal agents and bronchial thermoplasty are provided.Coordinated research efforts for improved phenotyping will provide safe and effective biomarker-driven approaches to severe asthma therapy.

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Section: Remarksmentioning

confidence: 99%

Section: Remarksmentioning

confidence: 99%

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

et al. 2013

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“…(12,20) Clinical data, such as spirometry results, as well as data related to use of medication and to quality of life, were also collected in order to improve the description of the asthma status associated with a given psychiatric profile.…”

Section: Discussionmentioning

confidence: 99%

“…(5)(6)(7)(8) Psychiatric disorders, mostly anxiety and depression, have been associated with asthma. (9)(10)(11)(12)(13) Asthma patients and patients with anxiety both exhibit a defensive behavior; the former, because of their repressive style of coping, might have an impaired ability to perceive asthma symptoms, a necessary prerequisite for following a personal asthma action plan, and the latter might have a heightened perception of their symptoms. (6,14) Therefore, the presence of anxiety or depression could affect the results of a self-administered multidimensional questionnaire such as the ACT.…”

Section: Introductionmentioning

confidence: 99%

Ansiedade e depressão em pacientes com asma: impacto no controle da asma

et al. 2011

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Objective: There is evidence that asthma is associated with an increase in psychiatric symptoms and mental disorders. This association can make it difficult to achieve asthma control. The purpose of this study was to determine whether the level of asthma control is associated with anxiety and depression. Methods: A crosssectional study involving 78 patients with confirmed moderate or severe asthma and under regular treatment at the Asthma Outpatient Clinic of the Federal University of São Paulo Hospital São Paulo, in the city of São Paulo, Brazil.The patients were divided into two groups by asthma control status, as assessed by the asthma control test, and were subsequently compared in terms of demographic, clinical, and spirometric data, as well as scores for asthma quality of life and hospital anxiety/depression. Results: The sample was predominantly female. Of the 78 patients, 49 (63%) were classified as having uncontrolled asthma. The prevalence of anxiety and of anxiety+depression was significantly higher among patients with uncontrolled asthma than among those with controlled asthma (78% and 100%; p = 0.04 and p = 0.02, respectively), whereas there were no differences between the two groups in terms of the prevalence of depression, spirometry results, or quality of life score. Conclusions: In this sample, the prevalence of anxiety symptoms was higher in the patients with uncontrolled asthma than in those with controlled asthma.In the evaluation of asthma patients, the negative impact of mood states ought to be taken into consideration when asthma control strategies are being outlined.Keywords: Asthma; Anxiety; Depression; Cross-sectional studies. ResumoObjetivo: Existem evidências da associação entre asma e sintomas psiquiátricos e transtornos mentais. Essa associação pode resultar em dificuldades de se atingir o controle da asma. O objetivo deste estudo foi avaliar a associação de ansiedade e depressão com o controle da asma. Métodos: Estudo transversal com 78 pacientes asmáticos com diagnóstico confirmado de asma moderada a grave e regularmente tratados no Ambulatório de Asma do Hospital São Paulo da Universidade Federal de São Paulo, São Paulo (SP).Os pacientes foram divididos em dois grupos em relação ao status de controle de asma, determinado através do teste de controle da asma, e, posteriormente, comparados em termos de dados demográficos, clínicos e espirométricos, escore do questionário de qualidade de vida para asma e escore da escala hospitalar de ansiedade e depressão. Resultados: A maioria era do sexo feminino. Dos 78 pacientes, 49 (63%) foram classificados como tendo asma não controlada. A prevalência de ansiedade e do binômio ansiedade/depressão foi significantemente maior entre os pacientes não controlados do que nos controlados (78% e 100%; p = 0,04 e p = 0,02, respectivamente), enquanto nem prevalência de depressão, nem os dados espirométricos ou de qualidade de vida diferiram entre os grupos. Conclusões: Nesta amostra, os pacientes com asma não controlada apresentaram uma maior p...

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“…9 However, depression is commonly not recognized or treated in patients with asthma. 1,2,17,18 Thus, tools to facilitate the detection of clinically significant depressive symptoms and to measure response to treatment in patients with asthma are needed.…”

Section: Introductionmentioning

confidence: 99%

The Quick Inventory of Depressive Symptomatology-Self-report: a psychometric evaluation in patients with asthma and major depressive disorder

Brown

Murray

Carmody

et al. 2008

Annals of Allergy, Asthma & Immunology

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Prevalence of psychiatric morbidity in a difficult asthma population: Relationship to asthma outcome

Cited by 90 publications

References 24 publications

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

Ansiedade e depressão em pacientes com asma: impacto no controle da asma

The Quick Inventory of Depressive Symptomatology-Self-report: a psychometric evaluation in patients with asthma and major depressive disorder

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