Prevalence of preterm premature rupture of membrane and its associated factors among pregnant women admitted in Debre tabor general hospital, North West Ethiopia: A facility based cross-sectional study

Abstract

Background: Premature rupture of membrane is a significant cause of maternal and neonatal morbidity and mortality both in high and low income countries which accounts 5-10 % of all deliveries. Due to different factors associated with the quality of health care given and socio-economic factors, the effect of preterm premature rupture of membrane is worsen in low-income countries. However, very little evidence is known about the problem in Ethiopian particularly in the study area. Therefore, this study was aimed to determine the prevalence of preterm premature rupture of membrane and its associated factors among pregnant women admitted in Debre tabor general hospital. METHODS: Facility based cross-sectional study was conducted at Debre tabor general Hospital from December 14 – June 20, 2019. A total of 424 mothers were included in the study. Systematic random sampling technique was used selected the study participants. A combination of chart review and interview were used to collect the data. Data entry and analysis were made by using Epi-data version 4.2 and SPSS versions 23 respectively. Both descriptive & analytical statistics were computed. Statistical significance was considered at P<0.05 and the strength of association were assessed by using adjusted odds ratio. Result: The prevalence preterm premature rupture of membrane was found to be 13.7%. Pregnant women with abnormal vaginal discharge [AOR=5.30, 95%C1=2.07-13.52], urinary tract infection [AOR =2.62, 95%Cl =1.32-5.19], history of premature rupture of membrane [AOR =3.31, 95%Cl =1.32-8.27], vaginal bleeding [AOR =2.58, 95%Cl =1.14-5.82] and mid upper arm circumstance <23cm [AOR =6.26, 95%Cl =3.21-12.20] were found to be associated with preterm premature rupture of membrane. Conclusions: The prevalence of preterm premature rupture of membrane was high. Abnormal vaginal discharge, urinary tract infection, vaginal bleeding, previous premature rupture of membrane and mid upper arm circumstance <23cm were factors associated with an increased risk for preterm premature rupture of membrane. Thus, early screening, diagnosis and quickly treatments of urinary tract infection and abnormal vaginal discharges during pregnancy were recommended to reduce the risk of preterm premature rupture of membrane. Keywords: premature rupture of membrane, prevalence, Debre tabor general hospital, risk factors