Prevalence of polymyxin resistant bacterial strains in India: a systematic review and meta-analysis
Sambit K. Dwibedy,
Indira Padhy,
Aditya K. Panda
et al.
Abstract:IntroductionPolymyxins, the cationic lipopeptide antibiotics, are considered to be the last line of therapeutics against the multi-drug resistant (MDR) pathogenic Gram-negative bacteria. Unfortunately, the rising cases of polymyxin-resistant strains from across the globe have adversely impacted the available treatment options. While the molecular mechanisms responsible for developing polymyxin resistance (PolR) are understood to a great extent, the prevalence of PolRstrains in India is not investigated systema… Show more
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