2011
DOI: 10.1590/s1413-86702011000100005
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Prevalence of pneumococcal serotypes and resistance to antimicrobial agents in patients with meningitis: ten-year analysis

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Cited by 5 publications
(7 citation statements)
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“…From 1988 to 1999, 31.8% (55/173) of the isolates presented nonsusceptibility to penicillin, with a mean MIC of 1 g/ml (range, 0.12 to 4 g/ml). From 2000 to 2011, 69.7% (99/142) of the isolates were PNSP, with an average MIC of 2 g/ml (range: 0.12 to 16 g/ml), supporting previous studies that have shown higher PNSP rates and MIC levels among isolates recovered in the 2000s compared to those obtained in the 1990s (7,9,10,12). Among PNSP isolates included in the present study, CC156 was largely represented, followed by CC66.…”
Section: Discussionsupporting
confidence: 85%
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“…From 1988 to 1999, 31.8% (55/173) of the isolates presented nonsusceptibility to penicillin, with a mean MIC of 1 g/ml (range, 0.12 to 4 g/ml). From 2000 to 2011, 69.7% (99/142) of the isolates were PNSP, with an average MIC of 2 g/ml (range: 0.12 to 16 g/ml), supporting previous studies that have shown higher PNSP rates and MIC levels among isolates recovered in the 2000s compared to those obtained in the 1990s (7,9,10,12). Among PNSP isolates included in the present study, CC156 was largely represented, followed by CC66.…”
Section: Discussionsupporting
confidence: 85%
“…Antimicrobial resistance rates among pneumococcal isolates can vary according to the clinical condition, patient age, geographical region, and serotype of the pneumococcal strain. In this context, several studies performed with pneumococcal isolates from Brazil have suggested that serogroup 9 and serotype 14 are among the most important capsular types driving the emergence of PNSP in our region (6)(7)(8)(9)(10)(11)(12)(13). In the present study, nearly half of the serogroup 9 and 14 isolates were PNSP, confirming that nonsusceptibility to penicillin is very common among these serotypes in Brazil.…”
Section: Discussionsupporting
confidence: 83%
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“…In a study carried out in Brazil on the meningitis patients varying one month old to 85 y old, serotypes of 5, 23F, 18C, 10A, 6B, 6A, 7F, 3, 19F, 14, and 34 were found [16].…”
Section: Discussionmentioning
confidence: 99%
“…Significant increases in the penicillin-resistance rates of invasive pneumococcal strains have been reported in Brazil. 16 Pneumococcal infections, which may be seen in every age group, may result in severe sequel or death due to treatment failures caused by bacterial resistance, especially if they occur in life-threatening locations. Thus, knowledge on pneumococcal resistance patterns enables initiation of an appropriate treatment.…”
Section: Discussionmentioning
confidence: 99%