volume 11, issue 8, Pe0157949 2016
DOI: 10.1371/journal.pone.0157949
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Abstract: BackgroundPlasmodium falciparum encoded histidine rich protein (HRP2) based malaria rapid diagnostic tests (RDTs) are used in India. Deletion of pfhrp2 and pfhrp3 genes contributes to false negative test results, and large numbers of such deletions have been reported from South America, highlighting the importance of surveillance to detect such deletions.MethodsThis is the first prospective field study carried out at 16 sites located in eight endemic states of India to assess the performance of PfHRP2 based RD…

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