Prevalence of Peripheral Arterial Disease and Related Risk Factors in an Urban Mexican Population

Buitrón-Granados, Luisa Virginia; Martínez-López, Carlos; Peña, Jorge Escobedo de la

doi:10.1177/000331970405500107

Cited by 15 publications

(11 citation statements)

References 20 publications

(8 reference statements)

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“…The data was not statistically significant (p=0.5). This is in concordance with the study done by Eason SL et al, 20 Buitrón LV et al 21 which showed that the presence of either signs or symptoms was more frequent in subjects with PAD.…”

Section: Abpi Value Cases Controlssupporting

confidence: 93%

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Prevalence of Peripheral Vascular Disease in Chronic Alcoholics as Measured by Ankle to Brachial Index

Singh¹,

Nayyar²,

Khurana³

2015

jemds

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ABSTRACT:The ankle-brachial pressure index (ABI), which is the ratio of ankle to brachial systolic blood pressure, is the golden standard for the diagnosis of peripheral arterial disease (PAD) and is a highly specific method for the assessment of vascular risk in otherwise asymptomatic patients . ABI value of individual with daily alcohol level >60g/d was significantly lower consumption of less than 60g/d had an inverse association with peripheral atherosclerosis whereas consumption of 60 g/d or more had a positive association. Studies have shown the sensitivity of ABPI is 90% with a corresponding 98% specificity for detecting hemodynamically significant (Serious) stenosis >50% in major leg arteries, defined by angiogram. AIMS AND OBJECTIVES: To determine the prevalence of peripheral vascular disease in chronic alcoholics using ankle to brachial index and to compare the values of ankle brachial index in chronic alcoholics with age and sex matched healthy controls. MATERIALS AND METHODS:In the present study, 50 cases consuming more than 60gm of absolute alcohol per day for more than 12 months attending outpatient department and admitted were enrolled. 50 age and sex matched healthy controls who have never consumed alcohol (never drinkers) were also enrolled. After taking detailed history using Doppler ultrasound blood flow detector mean systolic pressure in upper limb and lower limb was calculated and then the mean ABI was calculated. This value was then compared with variables like LDL levels, Triglycerides levels, age, clinical symptoms of PVD, alcohol consumption amount and duration. RESULTS: It was observed that mean ABI was significantly lower (<0.9) in 11(22%) cases and majority of them were between age group of 41-50 years. Of these only 7(14%) showed clinical symptoms of PVD. The prevalence of PVD was 66% in those who consumed 61-70 grams alcohol per day for around 6-10 years. Results were found to be statistically significant. CONCLUSION: This study was able to establish a direct association between peripheral vascular disease (ABI<0.9) and alcohol consumption above 60gms/day for more than 1yr duration. Chronic alcoholics with peripheral vascular disease also had increased level of HDL and LDL cholesterol.

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Section: Abpi Value Cases Controlssupporting

confidence: 93%

“…23 Buitrón-Granados LV et al studied prevalence of peripheral arterial disease and related risk factors in an urban Mexican population. 21 They included 400 adult subjects and finally concluded that serum triglycerides ≥150mg/dL was one of the risk factors related to PAD.…”

Section: Abpi Value Cases Controlsmentioning

confidence: 99%

Prevalence of Peripheral Vascular Disease in Chronic Alcoholics as Measured by Ankle to Brachial Index

Singh¹,

Nayyar²,

Khurana³

2015

jemds

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“…Data sources for ABI: urban China [67], urban Mexico [68], South Africa [28], southeast Spain [69], Sweden (Sigvant Birgitta pers comm), Thailand [70], United States [9]. Hypertension data for the same countries come from the World Health Organization Global Infobase, http://www.who.int/infobase/report.aspx.…”

Section: Resultsmentioning

confidence: 99%

Inflammation and Infection Do Not Promote Arterial Aging and Cardiovascular Disease Risk Factors among Lean Horticulturalists

et al. 2009

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BackgroundArterial aging is well characterized in industrial populations, but scantly described in populations with little access to modern medicine. Here we characterize health and aging among the Tsimane, Amazonian forager-horticulturalists with short life expectancy, high infectious loads and inflammation, but low adiposity and robust physical fitness. Inflammation has been implicated in all stages of arterial aging, atherogenesis and hypertension, and so we test whether greater inflammation associates with atherosclerosis and CVD risk. In contrast, moderate to vigorous daily activity, minimal obesity, and low fat intake predict minimal CVD risk among older Tsimane.Methods and FindingsPeripheral arterial disease (PAD), based on the Ankle-Brachial Index (ABI), and hypertension were measured in Tsimane adults, and compared with rates from industrialized populations. No cases of PAD were found among Tsimane and hypertension was comparatively low (prevalence: 3.5%, 40+; 23%, 70+). Markers of infection and inflammation were much higher among Tsimane than among U.S. adults, whereas HDL was substantially lower. Regression models examine associations of ABI and BP with biomarkers of energy balance and metabolism and of inflammation and infection. Among Tsimane, obesity, blood lipids, and disease history were not significantly associated with ABI. Unlike the Tsimane case, higher cholesterol, C-reactive protein, leukocytes, cigarette smoking and systolic pressure among North Americans are all significantly associated with lower ABI.ConclusionsInflammation may not always be a risk factor for arterial degeneration and CVD, but instead may be offset by other factors: healthy metabolism, active lifestyle, favorable body mass, lean diet, low blood lipids and cardiorespiratory health. Other possibilities, including genetic susceptibility and the role of helminth infections, are discussed. The absence of PAD and CVD among Tsimane parallels anecdotal reports from other small-scale subsistence populations and suggests that chronic vascular disease had little impact on adult mortality throughout most of human evolutionary history.

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“…7 Reported prevalences of PAD range from 4% to 27%. [8][9][10] Data on PAD in the Thai population are scarce. Up to now there has been no population-based study published on the prevalence of PAD in Thailand.…”

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confidence: 99%

Prevalence and Risk Factors of Peripheral Arterial Disease in a Selected Thai Population

Sritara

Woodward

et al. 2007

Angiology

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Peripheral arterial disease (PAD) is a condition with high mortality, but it is amenable to secondary prevention. Data on its prevalence in Thailand are scarce. To study the prevalence of PAD in a middle-class, urban Thai population, a cross-sectional study was conducted at the Electric Generating Authority of Thailand's head plant, Nonthaburi, in 2002 and 2003 on all surviving and contactable employees and former employees who had participated in the first cardiovascular risk factors survey in 1985. Participants completed a structured questionnaire detailing their medical history, and they underwent a physical examination. A diagnosis of PAD was made when the ankle-brachial index (ABI) was < 0.9. Ankle-brachial index data were available for 98% of participants in the survey; 75% were men, and participants' ages ranged from 52 to 73 years. The overall prevalence of PAD was 5.2%. The age-standardized prevalence of PAD was 4% in men and 9% in women. Multiple logistic regression analysis found hypertension (OR = 1.7), female gender (OR = 1.9), current smoking (OR = 3.0), current alcohol drinking (OR = 0.41), and overweight (body mass index [BMI] > 25 kg/m( 2), OR = 0.54) to be significant (P < .05) predictors of PAD. The prevalence of PAD in urban, middle-class Thais was similar to that in the population in developed countries.

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Prevalence of Peripheral Arterial Disease and Related Risk Factors in an Urban Mexican Population

Cited by 15 publications

References 20 publications

Prevalence of Peripheral Vascular Disease in Chronic Alcoholics as Measured by Ankle to Brachial Index

Prevalence of Peripheral Vascular Disease in Chronic Alcoholics as Measured by Ankle to Brachial Index

Inflammation and Infection Do Not Promote Arterial Aging and Cardiovascular Disease Risk Factors among Lean Horticulturalists

Prevalence and Risk Factors of Peripheral Arterial Disease in a Selected Thai Population

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