Prevalence of periodontitis in dentate people between 2011 and 2020: A systematic review and meta‐analysis of epidemiological studies

Abstract

Aim The aim of the study was to evaluate the prevalence of periodontitis in dentate people between 2011 and 2020. Materials and Methods PUBMED, Web of Science, and LILACS were searched up to and including December 2021. Epidemiological studies reporting the prevalence of periodontitis conducted between 2011 and 2020 were eligible for inclusion in this review. Studies were grouped according to the case definition of confidence as confident (Centers for Disease Control [CDC] AAP 2012; CDC/AAP 2007; and Armitage 1999) and non‐confident (community periodontal index of 3 or 4, periodontal pocket depth >4 mm, and clinical attachment level ≥1 mm). Random effects meta‐analyses with double arcsine transformation were conducted. Sensitivity subgroup and meta‐regression analyses explored the effect of confounding variables on the overall estimates. Results A total 55 studies were included. The results showed a significant difference, with confident case definitions (61.6%) reporting nearly twice the prevalence as non‐confident classifications (38.5%). Estimates using confident periodontal case definitions showed a pooled prevalence of periodontitis of 61.6%, comprising 17 different countries. Estimates reporting using the CDC/AAP 2012 case definition presented the highest estimate (68.1%) and the CDC/AAP 2007 presented the lowest (48.8%). Age was a relevant confounding variable, as older participants (≥65 years) had the highest pooled estimate (79.3%). Conclusion Between 2011 and 2020, periodontitis in dentate adults was estimated to be around 62% and severe periodontitis 23.6%. These results show an unusually high prevalence of periodontitis compared to the previous estimates from 1990 to 2010.

Bioinformatic evaluation of the potential oral-gut translocation of periodontal pathogens in patients with colorectal polyps

“…Periodontitis, a chronic inflammatory disease affecting the tissue around teeth, can lead to alveolar bone destruction and eventual tooth loss if untreated 1 . A recent systematic review found that the global prevalence of periodontitis has increased to approximately 60% in the last decade (2011–2020), surpassing previous estimates from 1990 to 2010 2 . Its adverse effects extend beyond the oral cavity, influencing the onset and progression of systemic diseases such as cardiovascular disease, respiratory infections, and diabetes 3,4 .…”

The role of the CX3CL1/CX3CR1 axis as potential inflammatory biomarkers in subjects with periodontitis and rheumatoid arthritis: A systematic review

“…1 Periodontitis is considered the sixth most common osteolytic disease affecting humans, 2 has a prevalence of 62.3%, and in its most severe form, can affect up to 23.6% of the world population. 3 The most current classification proposed by the global workshop is based on the complexity/severity and progression of the disease represented by Stages I-IV and Grades A-C. 4 Affected individuals clinically present bleeding on probing (BOP), suppuration, dental mobility, changes in the levels of insertion (clinical attachment loss [CAL]), and bone loss, ultimately leading to extraction or loss of teeth, which has a significant impact on the individual's oral health-related quality of life. 5 Therefore, its diagnosis is by clinical and radiographic examination.…”

“…Periodontitis is a chronic and multifactorial inflammatory disease caused by constant exposure to a polymicrobial dysbiotic film with a high prevalence of Gram‐negative bacteria such as Prevotella intermedia , Fusobacterium nucleatum , Aggregatibacter actinomycetemcomitans , Porphyromonas gingivalis , Tannerella forsythia , and Treponema denticola , and in the presence of a dysregulated immune response in a genetically susceptible host 1 . Periodontitis is considered the sixth most common osteolytic disease affecting humans, 2 has a prevalence of 62.3%, and in its most severe form, can affect up to 23.6% of the world population 3 . The most current classification proposed by the global workshop is based on the complexity/severity and progression of the disease represented by Stages I–IV and Grades A–C 4 .…”

Periodontitis and hypertension are linked through systemic inflammation: A 5‐year longitudinal study

“…Periodontitis is a chronic inflammatory disease associated with dysbiotic subgingival biofilms. It is highly prevalent, affecting about 60% of adults worldwide (Trindade et al, 2023). Cross‐sectional and case–control studies have indicated that periodontitis is associated with an increased likelihood of hypertension (Munoz Aguilera et al, 2020).…”