Prevalence of patients treated with antidepressant medicine in Greenland and Denmark: a cross-sectional study

Ingemann, Tukummeq Nykjær; Backe, Marie Balslev; Bonefeld-Jörgensen, Eva Cecilie; Skovgaard, Nils; Pedersen, Michael Lynge

doi:10.1080/22423982.2021.1912540

Cited by 5 publications

(6 citation statements)

References 24 publications

(30 reference statements)

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“…The observed lower prevalence of patients receiving ULT in Greenland compared to Denmark is in line with previous studies investigating the prevalence of patients treated with antidiabetics and anti-depressive medicine also finding a lower prevalence in Greenland compared to Denmark [ 10 , 19 ]. The difference between Greenland and Denmark might be due to an actual lower prevalence of patients with gout in Greenland compared to Denmark.…”

Section: Discussionsupporting

confidence: 90%

“…The healthcare system in Denmark consists of a primary and secondary sector. The primary sector includes general practitioners with the authority to refer patients to the secondary sector, which includes hospitals and other specialized medical units, such as private specialists [ 10 ].…”

Section: Methodsmentioning

confidence: 99%

“…Healthcare services are free of charge in both countries. In Greenland, prescribed medicine is also free of charge, whereas it requires a payment from the patient in Denmark [ 10 ].…”

Section: Methodsmentioning

confidence: 99%

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Prevalence of Patients Receiving Urate-Lowering Medicine in Greenland and Denmark: A Cross-Sectional Case–Control Study

Hull

Andersen

Bengtsson

et al. 2022

IJERPH

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This study estimates the age- and sex-specific prevalence of patients receiving urate-lowering therapy (ULT) in Greenland and compares the results with estimates in Denmark. Characteristics of patients receiving ULT in Greenland were compared to age- and sex-matched controls. The study was designed as a cross-sectional case–control study based on nationwide data from medical and population registers in Greenland and Denmark. The prevalence of patients receiving ULT was significantly lower in Greenland (0.55%) compared to Denmark (1.40%) (p < 0.001). In both countries, the prevalence increased with age and was higher among men compared to women. In Greenland, patients receiving ULT were more often overweight, and more frequently received blood glucose-, lipid-, and blood pressure-lowering medicine including diuretics compared to age- and sex-matched controls. The prevalence of patients receiving ULT was significantly lower in Greenland compared to Denmark. Common life-style related risk factors for hyperuricemia and gout were observed frequently among ULT-treated patients compared to controls. Along with an increasing prevalence of lifestyle-related diseases in Greenland, the prevalence of patients receiving ULT may increase in the years to come. More focus on detection and management of hyperuricemia and gout in Greenland is warranted to improve quality of health care.

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Section: Discussionsupporting

confidence: 90%

Section: Methodsmentioning

confidence: 99%

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Prevalence of Patients Receiving Urate-Lowering Medicine in Greenland and Denmark: A Cross-Sectional Case–Control Study

Hull

Andersen

Bengtsson

et al. 2022

IJERPH

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“…Among them, 10% used more than 180 defined daily doses (DDDs) per year 31. In addition to these significant changes in prescriptions and use over time, the prevalence in antidepressant drug use also varies according to age,12 14 sex,12 country14 25 32 33 and antidepressant agent or class 17 32 34…”

Section: Introductionmentioning

confidence: 99%

Global prevalence of antidepressant drug utilization in the community: protocol for a systematic review

et al. 2022

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IntroductionAntidepressant drugs are the most frequently prescribed medication for mental disorders. They are also used off-label and for non-psychiatric indications. Prescriptions of antidepressants have increased in the last decades, but no systematic review exists on the extent of their use in the community.Methods and analysisWe will conduct a systematic review to estimate the prevalence of antidepressant use in the community. We will search for studies published from 1 January 2010 in the Embase and MEDLINE databases using a combination of controlled vocabulary and keywords adjusted for each database without any language restriction. The main inclusion criterion is the presence of prevalence data of antidepressant utilization. Thus, we will include all studies with a descriptive observational design reporting the prevalence of antidepressant use in the community. Study selection (by title/abstract and full-text screening) and data extraction for included studies will be independently conducted by pairs of reviewers. We will then synthesize the data on the prevalence of antidepressant use in individuals living in the community. If possible, we will perform a meta-analysis to generate prevalence-pooled estimates. If the data allows it, we will conduct subgroup analyses by antidepressant class, age, sex, country and other sociodemographic categories. We will evaluate the risk of bias for each included study through a quality assessment using the Joanna Briggs Institute Critical Appraisal tool: Checklist for Studies Reporting Prevalence Data. DistillerSR software will be used for the management of this review.Ethics and disseminationEthical approval is not required for this review as it will not directly involve human or animal subjects. The findings of our systematic review will be disseminated through publications in peer-reviewed journals, the Qualaxia Network (https://qualaxia.org), presentations at international conferences on mental health and pharmacoepidemiology, as well as general public events.PROSPERO registration numberCRD42021247423.

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“…Among them, 10% used more than 180 defined daily doses (DDDs) per year (31). In addition to these significant changes in prescriptions and use over time, the prevalence in antidepressant drug use also varies according to age (12, 14), sex (12), country (14, 25, 32, 33) and antidepressant agent or class (17, 32, 34).…”

Section: Introductionmentioning

confidence: 99%

Global prevalence of antidepressant utilization in the community: A protocol for a systematic review

Lunghi

Dugas

Leclerc

et al. 2022

Preprint

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Background Antidepressant drugs are the most frequently prescribed medication for mental disorders. They are also used off-label and for non-psychiatric indications. Prescriptions of antidepressants have increased in the last decades, but no systematic review exists on the extent of their use in the community. Methods and analysis We will conduct a systematic review to estimate the prevalence of antidepressant use in the community. We will search for studies published from 2010 in the Embase and MEDLINE databases. Study selection (by title/abstract and full-text screening) and data extraction for included studies will be independently conducted by pairs of reviewers. We will then synthesize the data on the prevalence of antidepressant use in individuals living in the community. If possible, we will perform a meta-analysis to generate prevalence-pooled estimates. If the data allows it, we will conduct subgroup analyses by antidepressant class, age, sex, country or other sociodemographics. We will evaluate the risk of bias for each included study through a quality assessment using the Joanna Briggs Institute Critical Appraisal tool: Checklist for Studies Reporting Prevalence Data. DistillerSR software will be used for the management of this review. Ethics and dissemination Ethical approval is not required for this review as it will not involve human or animal subjects. The findings of our systematic review will be disseminated through publications in peer-reviewed journals, the Qualaxia Network (https://qualaxia.org), presentations to international conferences on mental health and pharmacoepidemiology, as well as general public events. PROSPERO registration details CRD42021247423

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Prevalence of patients treated with antidepressant medicine in Greenland and Denmark: a cross-sectional study

Cited by 5 publications

References 24 publications

Prevalence of Patients Receiving Urate-Lowering Medicine in Greenland and Denmark: A Cross-Sectional Case–Control Study

Prevalence of Patients Receiving Urate-Lowering Medicine in Greenland and Denmark: A Cross-Sectional Case–Control Study

Global prevalence of antidepressant drug utilization in the community: protocol for a systematic review

Global prevalence of antidepressant utilization in the community: A protocol for a systematic review

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