Prevalence of Parkinson?s disease and other types of Parkinsonism

Bergareche, Alberto; Puente, E. de la; Munáin, Adolfo López de; Sarasqueta, Cristina; Arce, Ana de; Poza, Juan José; Martí-Massó, J F

doi:10.1007/s00415-004-0333-3

Cited by 59 publications

(24 citation statements)

References 20 publications

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“…Generally, PD is rare before age 60 (0.13%‐1.6%), increases with age, and can reach a maximum of 9% among people aged 80‐84. Thereafter (85‐89), prevalences decline and vary from 0.87% to 3.6% 3, 4, 5, 6, 7, 8, 9, 10. Incidence rates are also low for those aged 50‐59 and increase sharply afterward.…”

Section: Introductionmentioning

confidence: 99%

Parkinson's disease in Germany: prevalence and incidence based on health claims data

2016

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BackgroundIn Germany, epidemiological information on Parkinson's disease (PD) is rare and outdated. Considering aging populations, current prevalences and incidence rates about this age‐related disease would be important for adequate public health planning.MethodsWe used newly available health claims data sets from the largest German health insurer dating 2004‐2007 and 2007‐2010 with an analysis population in the base years of 491 038 persons aged 50 and older. Quarter‐specific information about ICD‐10 diagnoses and PD drug prescriptions from the inpatient and outpatient sectors was used to validate PD cases. Estimations were presented for two validation strategies relying on repeated PD diagnoses (SIa) and on one PD diagnosis followed by at least one PD drug prescription (SIb).ResultsThe standardized prevalence was 797 (SIb) to 961/100 000 persons (SIa), showing an age‐specific increase up to category 85‐89 and a decline thereafter. The standardized incidence rate was 192 to 229/100 000 person‐years with a similar age‐specific shape. Prevalences and incidences rates were higher for men compared to women in regard to age.ConclusionsHealth claims data are found to be suitable for PD assessment using the repeated diagnoses or PD drug prescriptions as necessary criteria.

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Section: Introductionmentioning

confidence: 99%

Parkinson's disease in Germany: prevalence and incidence based on health claims data

2016

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“…Recent studies estimate its prevalence to be 1.5% in persons older than 65 years [1]. Its clinical manifestations include 4 cardinal signs: tremor, rigidity, bradykinesia and postural instability.…”

Section: Introductionmentioning

confidence: 99%

A Prospective Study of Alterations in Balance among Patients with Parkinson’s Disease

Rossi¹,

Soto²,

Santos³

et al. 2009

Eur Neurol

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The aim of this study is to determine whether the balance problems experienced by Parkinson’s disease (PD) patients may in part be due to dysfunctional processing of vestibular information, and to search for factors that may help predict the risk of falls. We evaluated the balance of 45 idiopathic PD patients and 20 healthy subjects by means of computerized dynamic posturography using sensory organization tests (SOT), rhythmic weight shift (RWS) tests and limits of stability (LOS) tests; and by the timed up-and-go (TUG) test. PD patients had poorer scores in the SOT than controls for overall balance and vestibular and visual inputs. They also performed worse in RWS and LOS tests, and were slower in performing the TUG test. Hoehn-Yahr stage did not correlate with vestibular input. Balance impairment in PD patients involves deteriorated processing of vestibular input, but this deterioration is independent of disease progression. Falls are related to PD patients’ reduced limits of stability.

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“…The systematic review comprised 44 studies estimating prevalence or incidence rates of PD of which 21 studies reported age- and gender-specific prevalence as well as the size of the underlying population [14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34]. To supplement these data by studies that were published after 2004, an additional systematic literature search was performed using the same search strategy as described by von Campenhausen et al [10] (Fig.…”

Section: Methodsmentioning

confidence: 99%

Prevalence, Duration and Severity of Parkinson's Disease in Germany: A Combined Meta-Analysis from Literature Data and Outpatient Samples

Enders¹,

Balzer‐Geldsetzer²,

Riedel³

et al. 2017

Eur Neurol

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Background: Epidemiological data on the prevalence of Parkinson's disease (PD) in Germany are limited. The aims of this study were to estimate the age- and gender-specific prevalence of PD in Germany as well as the severity and illness duration. Summary: A systematic literature search was performed in 5 different databases. European studies were included if they reported age- and gender-specific numbers of prevalence rates of PD. Meta-analytic approaches were applied to derive age- and gender-specific pooled prevalence estimates. Data of 4 German outpatient samples were incorporated to calculate the proportion of patients with PD in Germany grouped by Hoehn and Yahr (HY) stages and disease duration. In the German population, 178,169 cases of PD were estimated (prevalence: 217.22/100,000). The estimated relative illness duration was 40% with less than 5 years, 31% with 5-9 years, and 29% with more than 9 years. The proportions for different HY stages were estimated at 13% (I), 30% (II), 35% (III), 17% (IV), and 4% (V), respectively. Key Message: We provide an up-to-date estimation of age- and gender-specific as well as severity-based prevalence figures for PD in Germany. Further community studies are needed to estimate population-based severity distributions and distributions of non-motor symptoms in PD.

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Prevalence of Parkinson?s disease and other types of Parkinsonism

Abstract: These prevalence rates are similar than those found in studies made in other European countries. The prevalence of both Parkinson's disease and other types of parkinsonism increased with age, with no significant differences between men and women.

Cited by 59 publications

References 20 publications

Parkinson's disease in Germany: prevalence and incidence based on health claims data

Parkinson's disease in Germany: prevalence and incidence based on health claims data

A Prospective Study of Alterations in Balance among Patients with Parkinson’s Disease

Prevalence, Duration and Severity of Parkinson's Disease in Germany: A Combined Meta-Analysis from Literature Data and Outpatient Samples

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