Prevalence of Overweight in a Multiethnic Pediatric Population

Wong, William W.; Myres, Dawnell; Fraley, J. Kennard; Smith, E O; Klish, William J.; Hollier, David R.

doi:10.3109/713926151

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…Proportionally, the ethnic distribution of our sample was similar to that of the city of Houston 38 and consistent with the large percentage of Hispanic children seen hospital-wide at Texas Children's Hospital (see Figure 1). This larger Hispanic population is because of Texas's geographic proximity to the border of Mexico.…”

Section: Study Populationsupporting

confidence: 78%

“…In light of reported ethnic differences in the prevalence of NAFLD, including cryptogenic cirrhosis or NASH among adults and adolescents, [37][38][39] the objectives of this study were to (1) further characterize ethnic-specific differences in elevation of ALT among obese children; (2) validate recent national trends that obese Hispanic children have the highest incidence of ALT elevation; (3) investigate the earliest ages at which significant ALT elevation occurs, specifically within the obese Hispanic population; and (4) determine the association between ALT elevation and fasting triglyceride levels, fasting insulin levels, or degree of obesity.…”

mentioning

confidence: 99%

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Age- and Ethnic-Specific Elevation of ALT Among Obese Children at Risk for Nonalcoholic Steatohepatitis (NASH): Implications for Screening

Leung

Williams

Fraley

et al. 2008

Clin Pediatr (Phila)

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The objectives are to: (1) characterize ethnic-specific differences in alanine aminotransferase (ALT) elevation among obese children, (2) investigate the earliest ages at which significant ALT elevation occurs, and (3) determine associations between ALT and biochemical parameters. A cohort of 134 multiethnic obese children and adolescents was analyzed retrospectively. ALT levels > or =45 U/L or <45 U/L, denoting high or normal risk, were used to categorize obese children's risk for developing nonalcoholic steatohepatitis. In all, 60% of Hispanics had high-risk ALT levels compared with 12% of whites and 8% of blacks. A significantly higher proportion of boys had ALT > or = 45 U/L (49.4%, vs 37.9% for girls, P = .002); 17.5% were Hispanic boys less than 7 years old. Obese Hispanic children, particularly boys, not only have higher ALT levels but present alarmingly young with high-risk levels. This study highlights a discrete subgroup of children who may present with fatty liver at a younger age and should be screened earlier.

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Section: Study Populationsupporting

confidence: 78%

mentioning

confidence: 99%

Age- and Ethnic-Specific Elevation of ALT Among Obese Children at Risk for Nonalcoholic Steatohepatitis (NASH): Implications for Screening

Leung

Williams

Fraley

et al. 2008

Clin Pediatr (Phila)

Self Cite

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“…Unfortunately, children are no different. In some areas of the United States, the prevalence of pediatric overweight is around 40% and pediatric obesity around 22% (2). The super-obese child is becoming a common sight.…”

Section: Obesity Surgery In Pediatricsmentioning

confidence: 99%