Prevalence of osteoporotic vertebral fracture in Spanish women over age 45

Herrera, Antonio; Mateo, Jesús; Albarova, Jorge Gil; Lobo-Escolar, Antonio; Martín, J.M.; Lopez‐Prats, Fernando A.; Mesa, Mónica; Ibarz, Elena; Gracia, Luis

doi:10.1016/j.maturitas.2014.12.004

Cited by 26 publications

(14 citation statements)

References 25 publications

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“…When multiple fractures are present the QOL is even poorer. In another study, osteoporotic vertebral fractures were found to have occurred in 1,549 (31.79%) patients in a survey of 5,000 women over 45 years of age 28 ) . Among them, 528 (34.08%) had simple fractures, and 1,021 had multiple fractures (65.92%).…”

Section: Discussionmentioning

confidence: 93%

The relationship between fracture and quality of life in Korean adults receiving treatment for osteoporosis based on the 2010 Korean Community Health Survey

Kim

Jun

Jeong³

et al. 2015

J Phys Ther Sci

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[Purpose] The purpose of this study was to investigate the relationship between fracture and quality of life in Korean adults receiving treatment for osteoporosis based on the 2010 Korean Community Health Survey (KCHS). [Subjects and Methods] This study utilized the raw data of the 2010 KCHS. In the survey, osteoporosis was assessed in 228,903 subjects, excluding 326 for whom there was insufficient data. There were 17,387 subjects with osteoporosis confirmed by a doctor’s diagnosis and 9,419 of them were being treated for osteoporosis at the time of the survey. [Results] Among the patients being treated, those with fractures had a significantly lower QOL than patients who did not experience fractures. The lower QOL scores were caused by hip, vertebral and wrist fractures, and in all cases, QOL was significantly lower. Greater numbers of fractures significantly lowered QOL scores compared to participants without fractures. [Conclusion] Fractures in patients receiving treatment for osteoporosis have a direct impact on QOL. Among the different types of fractures, hip fractures resulted in the lowest scores. Therefore, to avoid additional fractures caused by inappropriate management of osteoporosis, we suggest that there is a need to improve fall related self-efficacy and prevention programs.

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Section: Discussionmentioning

confidence: 93%

The relationship between fracture and quality of life in Korean adults receiving treatment for osteoporosis based on the 2010 Korean Community Health Survey

Kim

Jun

Jeong³

et al. 2015

J Phys Ther Sci

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“…2010, Herrera et al. 2015). Our study population therefore appears to be representative of patients with symptomatic AOVFs.…”

Section: Discussionmentioning

confidence: 99%

Concomitant and previous osteoporotic vertebral fractures

2017

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Background and purposePatients with osteoporosis who present with an acute onset of back pain often have multiple fractures on plain radiographs. Differentiation of an acute osteoporotic vertebral fracture (AOVF) from previous fractures is difficult. The aim of this study was to investigate the incidence of concomitant AOVFs and previous OVFs in patients with symptomatic AOVFs, and to identify risk factors for concomitant AOVFs.Patients and methodsThis was a prospective epidemiological study based on the Registry of Pathological Osteoporotic Vertebral Fractures (REPAPORA) with 1,005 patients and 2,874 osteoporotic vertebral fractures, which has been running since February 1, 2006. Concomitant fractures are defined as at least 2 acute short-tau inversion recovery (STIR-) positive vertebral fractures that happen concomitantly. A previous fracture is a STIR-negative fracture at the time of initial diagnostics. Logistic regression was used to examine the influence of various variables on the incidence of concomitant fractures.ResultsMore than 99% of osteoporotic vertebral fractures occurred in the thoracic and lumbar spine. The incidence of concomitant fractures at the time of first patient contact was 26% and that of previous fractures was 60%. The odds ratio (OR) for concomitant fractures decreased with a higher number of previous fractures (OR =0.86; p = 0.03) and higher dual-energy X-ray absorptiometry T-score (OR =0.72; p = 0.003).InterpretationConcomitant and previous osteoporotic vertebral fractures are common. Risk factors for concomitant fractures are a low T-score and a low number of previous vertebral fractures in cases of osteoporotic vertebral fracture. An MRI scan of the the complete thoracic and lumbar spine with STIR sequence reduces the risk of under-diagnosis and under-treatment.

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“…In this sense, menopausal and postmenopausal women are the demographic with the highest percentage of prevalence of osteoporosis, making up 30-50% of the world's population with osteoporosis [3]. In Spain, despite being considered a country of moderate risk, the prevalence rate is the same as the global rate, with osteoporotic fracture rates of 15% and which double every seven years as age progresses [4].…”

Section: Introductionmentioning

confidence: 99%

A Dairy Product to Reconstitute Enriched with Bioactive Nutrients Stops Bone Loss in High-Risk Menopausal Women without Pharmacological Treatment

et al. 2020

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Osteoporosis is a multifactorial disease characterized by the loss of bone mass and deterioration of the internal structure of the bone, increasing the risk of fractures, and is becoming an economic and social problem. The main treatment is pharmacological, however, the population demands other therapies, such as foods with nutrients beneficial to bone health. Seventy-eight healthy menopausal women at risk of osteoporosis or untreated osteopenia were recruited for a randomized, parallel, double-blind clinical trial with two intervention groups: one group consumed a serving a day of the experimental enriched product (experimental group (EG)) and the other group (control group (CG)) consumed the same product without enrichment. The main objective was to compare the effect of consuming a dairy preparation to reconstitute, similar to yogurt when prepared, enriched in calcium, vitamin D, vitamin K, vitamin C, zinc, magnesium, L-leucine and probiotic (Lactobacillus plantarum 3547) on bone metabolism markers for 24 weeks. The EG showed a significantly increased bone mass compared to the CG (0.01 ± 0.03 vs. −0.01 ± 0.03 kg; p < 0.05). In addition, the EG maintained their bone mineral density (BMD) compared to the CG, whose BMD significantly decreased at the end of the study. For biochemical markers, the EG significantly increased the serum levels of the N-terminal propeptide of type I collagen (P1NP) bone formation marker (13.19 ± 25.17 vs. −4.21 ± 15.62 ng/mL; p < 0.05), and decreased the carbo-terminal telopeptide of type I collagen (CTx) bone resorption marker compared to the CG (−0.05 ± 0.19 vs. 0.04 ± 0.14 ng/mL; p < 0.05). On the other hand, the EG exhibited a significantly decreased systolic and diastolic blood pressure compared to the start of the study. Finally, the EG significantly increased their dietary calcium and vitamin D intake compared to the CG. In conclusion, the regular consumption of a dairy product to reconstitute enriched with bioactive nutrients improves bone health markers in menopausal women at risk of osteoporosis without pharmacological treatment.

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Prevalence of osteoporotic vertebral fracture in Spanish women over age 45

Cited by 26 publications

References 25 publications

The relationship between fracture and quality of life in Korean adults receiving treatment for osteoporosis based on the 2010 Korean Community Health Survey

The relationship between fracture and quality of life in Korean adults receiving treatment for osteoporosis based on the 2010 Korean Community Health Survey

Concomitant and previous osteoporotic vertebral fractures

A Dairy Product to Reconstitute Enriched with Bioactive Nutrients Stops Bone Loss in High-Risk Menopausal Women without Pharmacological Treatment

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