Prevalence of Osteoarthritis, Osteoporotic Vertebral Fractures, and Spondylolisthesis among the Elderly in a Japanese Village

Horikawa, Kazuhiro; Kasai, Yuichi; Yamakawa, Toru; Sudo, Akihiro; Uchida, Atsushi

doi:10.1177/230949900601400103

Cited by 32 publications

(35 citation statements)

References 8 publications

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“…Of the 28 studies, 22 were community-based, including 22,925 subjects; 56% were female, the mean age ranged from 38.7 years to 74.7 years, and the mean body mass index (BMI) ranged from 23.0 to 30.4 [14][15][16][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50]. The most frequent study design was cross-sectional (N ¼ 18), followed by case-control (N ¼ 2) and cohort (N ¼ 1).…”

Section: Search and Selection Of Studiesmentioning

confidence: 99%

The association between lumbar spine radiographic features and low back pain: A systematic review and meta-analysis

Raastad¹,

Reiman

Coeytaux

et al. 2015

Seminars in Arthritis and Rheumatism

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Section: Search and Selection Of Studiesmentioning

confidence: 99%

The association between lumbar spine radiographic features and low back pain: A systematic review and meta-analysis

Raastad¹,

Reiman

Coeytaux

et al. 2015

Seminars in Arthritis and Rheumatism

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“…A retrospective study found that the prevalence of spinal OA was as high as 80% among Caucasian individuals aged 40 years and older [10]. However, in a study on elderly individuals in a Japanese village [11], 42% of men and 36% of women had radiographic OA of the spine.…”

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confidence: 99%

Osteoarthritis in southeast Asia

Nguyen¹

2014

International Journal of Clinical Rheumatology

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Keywords: osteoarthritis • osteoarthritis of the knee • osteoarthritis of the spine • southeast Asia • urbanization Osteoarthritis Osteoarthritis (OA) is a multifactorial and complex disease that involves change in articular bone and cartilage structure. The multifactorial nature of OA is that the disease is not a single entity, but encompasses many entities, including the the loss of cartilage within synovial joints, hypertrophy of bone, and thickening of the capsule. The complexity is in the causality and etiology of the disease as its risk is determined by multiple, and probably interactive, effects of genetic and environmental factors. A reasonable definition that can capture the complexity and multifactorial nature of the disease is "a heterogeneous group of conditions that lead to joint symptoms and signs, which are associated with defective integrity of of cartilage, in addition to related changes in the underlying bone at the joint margins" [1]. Although OA can affect any joint in the body, it is often found at the hands, knees, hips, and spine.A challenge in studies of OA is in the diagnosis. There is a considerable disparity between clinical and radiologic diagnoses. There are many radiologic methods for diagnosing OA, but the Empire Rheumatism Council system of grading first described by Kellgren and Lawrence [2] is probably the most widely used scale in epidemiologic studies. The Kellgren-Lawrence method is actually a system of OA grading based on the presence or absence of osteophytes, joint space narrowing, subchondral sclerosis, and bony cysts. In an epidemiologic study, it was noted that while the prevalence of clinically diagnosed knee OA was approximately 18%, the radiologically based method identified 25-30% [3]. The degree of diagnostic agreement of between clinical diagnosis and radiologic diagnosis was moderate [3], which was confirmed by a recent meta-analysis [4].However, with recent advances in imaging technology (e.g., MRI), there has been a shift in thinking about OA. Instead of being viewed as a 'tear and wear' disease, OA is now viewed as an active disease with disruption in processes involved in the maintenance of healthy cartilage [5]. Nevertheless, image-based diagnosis of OA has not been widely used in research studies [5].Prevalence of OA OA is the most common musculoskeletal disorder among the elderly, and women are more likely to be affected than men. A population-based analysis based on NHES survey data found that the prevalence of hand OA was 29.5% among those aged 25 years and older [6]. A recent analysis of NHANES III data found that approximately 35% of women and men aged 60 years and above had radiographic OA of the knee [7]. In a Chinese population aged ≥60 years, the prevalence of knee OA was 22% in men and 43% in women, and this prevalence was 45% higher than that in the US white population [8]. In a Japanese rural population, the prevalence of knee OA was 30% in women and 11% in men.Surprisingly, the prevalence of spinal OA has not been well documented. Based on a f...

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“…However, there is some evidence that a close relationship exists between osteoporosis and back pain [7,18]. This may be because osteoporosis could exist concurrently with osteoarthritis and musculoskeletal malfunction or atrophy [26][27][28], and confounding factors have not been appropriately controlled in investigations of the relationship between osteoporosis and back pain.…”

Section: Discussionmentioning

confidence: 99%

Bone mineral density is not associated with musculoskeletal pain in postmenopausal Korean women aged ≥50 years

et al. 2014

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Although many studies reported improvement of back pain after osteoporosis treatment, there is insufficient evidence to determine whether osteoporosis is painful. We investigated whether bone mineral density correlated with musculoskeletal pain in postmenopausal Korean women aged ≥50 years. Data for postmenopausal women aged ≥50 years were obtained from the fifth Korea National Health and Nutrition Examination Survey database. Demographics, Kellgren-Lawrence grade, and numeric rating scale for pain in the hip and knee joints, presence of back pain, and activity level were analyzed. Only subjects with dual-energy X-ray absorptiometry scans and hip and knee radiographs were included. Those with malignancy, pain medication use, or a history of fragility fractures were excluded. After univariate analysis, multiple linear regression analysis was performed to examine the significant factors correlated with the degree of hip and knee pain. Binary logistic regression analysis was performed to identify factors significantly associated with the presence of back pain. In total, 387 women were included in the data analysis. Age (p = 0.005) was the only significant factor correlated with the intensity of hip pain, while Kellgren-Lawrence grade (p < 0.001) was the only significant factor correlated with knee pain intensity in multiple regression analysis. Binary logistic regression analysis showed that age (p = 0.002) was the only significant factor associated with the presence of back pain. Musculoskeletal pain was not affected by or associated with the bone mineral density (BMD) of the affected body part in postmenopausal Korean women aged ≥50 years after adjusting for the degree of osteoarthritis.

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Prevalence of Osteoarthritis, Osteoporotic Vertebral Fractures, and Spondylolisthesis among the Elderly in a Japanese Village

Cited by 32 publications

References 8 publications

The association between lumbar spine radiographic features and low back pain: A systematic review and meta-analysis

The association between lumbar spine radiographic features and low back pain: A systematic review and meta-analysis

Osteoarthritis in southeast Asia

Bone mineral density is not associated with musculoskeletal pain in postmenopausal Korean women aged ≥50 years

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