Prevalence of oral squamous cell carcinoma of tongue in and around Davangere, Karnataka, India: A retrospective study over 13 years

Abstract

Aim:The aim was to determine the frequency and distribution of oral squamous cell carcinoma (OSCC) involving tongue among patients by studying biopsy specimens obtained from the archives of the Department of Oral and Maxillofacial Pathology, College of Dental Sciences, Davangere, Karnataka, India, during the past 13 years.Methodology:Data for the study were retrieved from the case records of patients. Analyzed clinical variables included age, sex, anatomical site, and histological diagnosis.Results:Of the 369 squamous cell carcinoma involving head and neck region, we found 52 biopsies reported exclusively involving tongue. Lateral border of the tongue was most commonly involved (43 cases, 82.7%), followed by base of tongue and posterior part of tongue. The patient were affected over a wide range of 27–80 years with mean age of 55.75 years and peak incidence was seen in the fourth and fifth decades of life, with the male: female ratio of 1.7:1.Conclusion:The prevalence rate of OSCC involving tongue showed a definite geographic variation when compared with a study done in other parts of the world.

Squamous cell carcinoma of the tongue in patients older than 45 years

“…In several studies, preference for males varied among 48% and 86.4% [18][19][20][21][22][23] and the male frequency we found (53.3%) is within the above-mentioned range. In the literature, mean age is widely variable, it was from 64.3 to 47.5 years, 18,[21][22][23][24] and in our study, it was slightly lower (63.9 years).…”

“…Our results are only similar to those from the Ramdass et al study, 21 but completely different to those found in other studies showing that the WD type was the most common followed by the moderately differentiated type. 18,22,23,24 It is interesting to note, that in this study, a high proportion of low risk patients developed SCCT. This data does not agree with previous studies showing that high risk patients comprise the high proportion of the analyzed samples.…”

“…An unexpected result was that in our study, the MDSCC was the most common of the analyzed tumors (56.7%), contrasting with previous data From Finland and India reporting that WDSCC was the most frequent SCCT. 20,23 50% of the analyzed patients were males with a mean age of 63.1 years and interestingly, 35.3% of the SCCs were in BT. BT located tumors were more frequent than previously published and as it was stated by Westra et al, 2 this finding could be related with the increase of HPV infection.…”

“…This data does not agree with previous studies showing that high risk patients comprise the high proportion of the analyzed samples. 21,22,23,24,25,26 Probably these differences may arise from difficulties in the evaluation of tobacco or alcohol consumption levels. This can occur when clinical histories are reviewed retrospectively.…”

A Study of Association of Clinical Profile With Histopathology of Oral Squamous Cell Carcinoma

“…Albuquerque et al [11] found 59.7% involving lateral borders of the tongue were the most frequent carcinoma. These results are similar to present study results, as we also found a most frequent site to be the lateral border of tongue and accounts for about 42.2%, 171 cases out of 405 studied.…”