Prevalence of Oral Mucosal Lesions and Relation to Serum Cotinine Levels—Findings from a Cross-Sectional Study in South Africa

Pontes, Carla Cruvinel; Chikte, Usuf; Kimmie-Dhansay, Faheema; Erasmus, Rajiv T; Kengne, André Pascal; Matsha, Tandi E.

doi:10.3390/ijerph17031065

Cited by 9 publications

(8 citation statements)

References 35 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To date, some studies have examined the epidemiology of OMD, but the prevalence rates are inconsistent in older adults across studies. The prevalence of OMD in older adults aged 60 and above is relatively high, ranging from 29.0% in Iran, over 33.3% in Australia, 41.2% in the USA, to 53% in Chile [35][36][37][38][39]. The pooled prevalence of OMD in this meta-analysis is significantly lower than the corresponding figures (29%-53%) reported from most of the Western countries, but not all (2%-3% in South Africa) [37].…”

Section: Discussioncontrasting

confidence: 65%

“…The prevalence of OMD in older adults aged 60 and above is relatively high, ranging from 29.0% in Iran, over 33.3% in Australia, 41.2% in the USA, to 53% in Chile [35][36][37][38][39]. The pooled prevalence of OMD in this meta-analysis is significantly lower than the corresponding figures (29%-53%) reported from most of the Western countries, but not all (2%-3% in South Africa) [37]. The discrepancy of the OMD rate between Chinese and Western studies in older adults could be due to several reasons.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies

Zhou

Zhang

Yan

et al. 2020

IJERPH

View full text Add to dashboard Cite

Oral mucosal disease (OMD) is a public health challenge globally, but the epidemiological findings in older adults have been inconsistent in China. Thus, this meta-analysis was carried out to explore the prevalence of OMD and its moderating factors in this population. An electronic literature search was conducted of both international (PubMed, PsycINFO, and EMBASE) and Chinese (China National Knowledge Infrastructure and WanFang) databases from inception to November 1, 2019. The Der–Simonian and Laird random effects model was used to synthesize the prevalence of OMD and its 95% confidence intervals (95% CI). Twenty-four studies covering 23,653 older adults were included. The pooled prevalence of OMD was 23% (95% confidence interval: 17.9%–29.0%) Subgroup analyses and meta-analysis revealed that the prevalence of OMD was significantly associated with the reporting sampling, year of publication, and survey (all p values <0.05). This meta-analysis found that the prevalence of OMD among older adults in mainland China was significantly high. Early detection and effective intervention of OMD in older adults have public health and clinical importance.

show abstract

Section: Discussioncontrasting

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies

Zhou

Zhang

Yan

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…Each year, tobacco use is responsible for approximately 8 million deaths worldwide, including 7 million deaths among persons who use tobacco and 1.2 million deaths among nonsmokers exposed to secondhand smoke (SHS) 19 . In addition to being associated with a number of cancers and coronary conditions, tobacco plays a role in the etiology of a number of oral conditions; tobacco exposes the oral cavity to toxic carcinogens that have a role in initiation and promotion of cancer 20 as well as leukoplakia, periodontitis, and delayed wound healing 21 . The dental practice setting thus provides a unique opportunity to assist tobacco users in achieving tobacco abstinence 17 .…”

Section: Discussionmentioning

confidence: 99%

Are Nigerian oral health workers overlooking opportunities to promote interventions for tobacco smoking cessation?

Oyapero¹,

Olatosi²,

Olagundoye³

2021

Popul. Med.

View full text Add to dashboard Cite

INTRODUCTION Since dentists are strategically positioned to promote tobacco abstinence and cessation, we assessed their commitment through their patients' dental history in one of the busiest tertiary dental clinics in Nigeria, and also aimed to assess factors associated with screening for tobacco use. METHODS This retrospective and descriptive study utilized the dental records of patients (aged 12-80 years) at the oral diagnosis unit of the Lagos State University Teaching Hospital (LSUTH), Nigeria, from 2017-2018. Descriptive statistics were used to quantify variables such as age, gender, history of tobacco use, while the outcome variable was provision of cessation assistance through referral to the preventive dentistry cessation clinic. Data were analyzed by χ 2 tests, t-test, and regression analysis. The significant level for statistical analysis was set at 5% (p≤0.05). RESULTS A total of 15786 new patients, mean age 49.3±12.8 years, were reviewed. Only 4104 (26%) of the patients had their tobacco use history documented; of these, 656 (16%) indicated past or current tobacco use; only 120 (18.3%) of these were referred for cessation counseling in the preventive dentistry unit. Males (n=611; 93.1%) had a higher proportion of past or present tobacco use. Patients presenting with oral ulcers (OR=1.94) and jaw tumors (OR=2.45) were significantly more likely to be screened for tobacco use. CONCLUSIONS Less than 0.01% of new patients were provided with tobacco use cessation advice, and opportunities for screening were essentially unexploited implying an urgent need to incorporate tobacco cessation interventions as part of standard clerking sheets for patients.

show abstract

“…However, nicotine has a short half-life, making it difficult to be used as a marker of exposure to cigarette smoke. On the other hand, cotinine, a metabolite of nicotine, has a long half-life of approximately 10-20 hours (22,23) and has been used in several studies to assess smoking status (24,25). Therefore, serum cotinine levels were used as an objective index in the present study.…”

Section: Introductionmentioning

confidence: 99%

Antibody response of smokers to the COVID-19 vaccination: Evaluation based on cigarette dependence

Mori

Tanaka

Kozai

et al. 2022

DD&T

View full text Add to dashboard Cite

SARS-CoV-2, COVID-19, mRNA vaccine, anti-RBD IgG level, cigarette dependence Smokers may have lower antibody titers after vaccination with a coronavirus disease 2019 (COVID-19) mRNA vaccine. However, to the best of our knowledge, no study has evaluated antibody titers after COVID-19 vaccination based on the level of smokers' cigarette dependence. In this study, we measured the level of serum anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) spike protein receptor-binding domain (S-RBD) immunoglobulin-G (IgG) by enzyme linked immunosorbent assay of 55 actively smoking Japanese social workers (firefighters, paramedics, and rescue workers) who had received two doses of the BNT162b2 vaccine. Further, we assessed their cigarette dependence using the Fagerstrom Test for Nicotine Dependence (FTND), measured their serum cotinine levels, and tested for their correlation with anti-RBD IgG levels. Serum anti-SARS-CoV-2 S-RBD protein IgG levels after BNT162b2 vaccination showed a significant negative correlation with FTND (ρ = -0.426, p = 0.001). In addition, serum cotinine level showed a significant positive correlation with FTND (ρ = 0.470, p = 0.000). However, no significant negative correlation was noted between serum cotinine and serum anti-SARS-CoV-2 S-RBD protein IgG levels (ρ = -0.156, p = 0.256). Our results suggest that smokers with strong cigarette dependence have inadequate anti-SARS-CoV-2 S-RBD protein IgG levels after COVID-19 mRNA vaccination.

show abstract

Prevalence of Oral Mucosal Lesions and Relation to Serum Cotinine Levels—Findings from a Cross-Sectional Study in South Africa

Cited by 9 publications

References 35 publications

Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies

Prevalence of Oral Mucosal Diseases in Older Adults in Mainland China: A Meta-Analysis of Observational Studies

Are Nigerian oral health workers overlooking opportunities to promote interventions for tobacco smoking cessation?

Antibody response of smokers to the COVID-19 vaccination: Evaluation based on cigarette dependence

Contact Info

Product

Resources

About