Prevalence of Obesity among Primary School Children Living in Egypt

Shafie, Ali M. El; Bahbah, Mohammed H; Omar, Zein A; Bahbah, Wael A.; Eladawy, Eman S.

doi:10.37506/v10/i12/2019/ijphrd/192434

Cited by 2 publications

(2 citation statements)

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“…There are approximately 2.1 billion overweight or obese persons in the world" [1]. "In Egypt, 15.02 percent of elementary school pupils were overweight, and 10.55 percent were obese" [2].…”

Section: Introductionmentioning

confidence: 99%

Effect of Metformin Combined with Dietary Intervention on Childhood Obesity and Insulin Resistance

Khater

El-Sawy²,

El-Shafiey³

et al. 2023

JAMMR

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Background: Obesity is a multifactorial disease with multiple comorbidities such as insulin resistance (IR), cardiovascular disease, diabetes mellitus, and hypertension. Puberty is physiologically responsible for IR. During this stage of life, insulin sensitivity decreases by 25–50% and then improves. A change in lifestyle that promotes healthy nutritional habits and physical activity, as well as complementary treatments such as metformin therapy, is recommended as the first line of treatment. Aim of the Work: To assess the effect of metformin combined with dietary intervention on BMI and IR in obese children and adolescents in the prepubertal and pubertal stages. Methods: This study included 90 children and adolescents divided into two groups: 60 obese children and adolescents with BMIs > the 95th percentile for their sex and age (30 prepubertal and 30 pubertal) and 30 healthy children and adolescents with BMIs between the 5th and 85th percentile for their sex and age (15 prepubertal and 15 pubertal). They underwent a thorough clinical evaluation, which included anthropometric measurements and investigations such as serum adiponectin, leptin, adiponectin-leptin ratio (ALR), plasminogen activator inhibitor-1 (PAI-1), a lipid profile, and HOMA-IR. Obese children and adolescents received metformin with dietary intervention for six months. Results: After the therapeutic intervention, the anthropometric measurements (weights, weight Z-scores, BMIs, BMI Z-scores, waist and hip circumferences, and waist-hip ratios) and the lipid profile (total serum cholesterol, LDL-C, HDL-C, and serum triglycerides) improved significantly in both obese groups (prepubertal and pubertal). Prepubertal obese children significantly improved more than pubertal obese children and adolescents in inflammatory adipokines (leptin, adiponectin, PAF-1, and ALR) and insulin sensitivity markers after the therapy. Conclusion: Puberty is a critical physiologic stage affecting the response to metformin, which should be studied further in pubertal obese children and adolescents, particularly the dose-effect relationship.

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“…There are approximately 2.1 billion overweight or obese persons in the world" [1]. "In Egypt, 15.02 percent of elementary school pupils were overweight, and 10.55 percent were obese" [2].…”

Section: Introductionmentioning

confidence: 99%

Effect of Metformin Combined with Dietary Intervention on Childhood Obesity and Insulin Resistance

Khater

El-Sawy²,

El-Shafiey³

et al. 2023

JAMMR

View full text Add to dashboard Cite

show abstract

“…In 2019, the World Obesity Federation predicted that by 2030, approximately 254 million children & adolescents of 5-19 y age will suffer obesity, up from 206 million in 2025 [2]. In Egypt, 15% of primary school children were overweight, while 10.5% were obese [3].…”

Section: Introductionmentioning

confidence: 99%

Effect of Omega-3 Polyunsaturated Fatty Acids Combined with Dietary Intervention on Childhood Obesity and Insulin Resistance

Seif,

Hamam,

El-Shafiey

et al. 2023

JAMMR

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Background: Obesity is one of the multifactorial diseases associated with numerous cardiometabolic comorbidity conditions and insulin resistance (IR). Modifying the lifestyle, like following healthy nutrition in addition to physical activity, is considered one of the main strategies for obesity management. Besides various treatment options, omega-3 polyunsaturated fatty acids (PUFAs) supplementation is suggested as a potential solution to alleviate several obesity-related issues. The work aimed: to assess the effects of omega-3 PUFAs in combination with dietary intervention on BMI and IR in children with obesity. Subjects and Methods: A prospective randomized controlled longitudinal study was carried out on sixty children & adolescents suffering from obesity with a BMI of ≥95th percentile for sex and age. They were categorized into 2 groups (thirty children in each group): group A received oral omega-3 PUFAs in addition to a dietary intervention for six months, and group B received only a dietary intervention during the same period. Another thirty healthy children & adolescents having BMI ranging from 5th to 85th percentile for sex and age were matched with the obese children groups for sex and age and served as controls. All participants included in the study underwent a history taking, thorough clinical assessment, anthropometric measurement, and various investigations such as ALT, AST, CRP, lipid profile, HOMA-IR, serum adiponectin, serum leptin, and adiponectin-leptin ratio (ALR). Results: After the therapeutic interventions, group A (omega-3-supplemented) showed significant improvement in waist circumference, serum triglycerides, HDL-C, inflammatory adipokines (that included leptin, adiponectin, and ALR) as well as markers for insulin sensitivity compared to group B. Conclusion: Combining omega-3 PUFAs with dietary intervention improved various obesity-related parameters, enhancing insulin sensitivity markers and reducing inflammatory adipokines in obese children and adolescents.

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Prevalence of Obesity among Primary School Children Living in Egypt

Cited by 2 publications

References 0 publications

Effect of Metformin Combined with Dietary Intervention on Childhood Obesity and Insulin Resistance

Effect of Metformin Combined with Dietary Intervention on Childhood Obesity and Insulin Resistance

Effect of Omega-3 Polyunsaturated Fatty Acids Combined with Dietary Intervention on Childhood Obesity and Insulin Resistance

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