Prevalence of new psychoactive substances (NPS) in Brazil based on oral fluid analysis of samples collected at electronic music festivals and parties

Cunha, Kelly Francisco da; Oliveira, Karina Diniz; Cardoso, Marilia Santoro; Arantes, Ana Carolina Furiozo; Coser, Pedro Henrique Piras; Lima, Lucas de Noronha; Maluf, Ana Cristhina Sampaio; Comis, Maria Angélica; Huestis, Marilyn A.; Costa, José Luiz

doi:10.1016/j.drugalcdep.2021.108962

Cited by 18 publications

(6 citation statements)

References 29 publications

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“…Differently from the survey, analytical data highlighted the presence of synthetic cannabinoids in the analyzed oral fluids at a positivity rate of 19.7%. In previously published studies, the detected positivity rate for NPS in oral fluid was around 7%–8% in non‐high‐risk populations [15, 21] (i.e., drivers) reaching up to 39% in case of high‐risk classes [27]. Notwithstanding the limited number of searched analytes, the study provided evidence of SCRA diffusion in the selected population.…”

Section: Discussionmentioning

confidence: 60%

Oral fluid analysis to monitor recent exposure to synthetic cannabinoids in a high‐risk subpopulation

Pascali

Dagoli

Antonioni³

et al. 2022

Journal of Forensic Sciences

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Section: Discussionmentioning

confidence: 60%

Oral fluid analysis to monitor recent exposure to synthetic cannabinoids in a high‐risk subpopulation

Pascali

Dagoli

Antonioni³

et al. 2022

Journal of Forensic Sciences

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“…da Cunha et al reported on the prevalence of NPSs in Brazil following sample collections at 13 electronic dance music events from September 2018 to January 2020 (da Cunha et al, 2021). MDMA, ketamine, methylone, N ‐ethylpentylone were the most detected psychoactive substances.…”

Section: Resultsmentioning

confidence: 99%

Trends and challenges in the use of drugs as forensic evidence: A scientometric approach to map the current literature

Norman,

Lim,

Henderson

et al. 2023

WIREs Forensic Science

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The rapid increase in the production and distribution of illicit drugs has led to vast amounts of data being generated through research and other publications, making it difficult to effectively distill and analyze current and emerging trends. The present study used a scientometric approach to identify trends and challenges in the use of drugs as an evidence type in forensic science by examining reference lists available in the INTERPOL IFSMS reports and the citation database Scopus. It has been identified that “new psychoactive substances” is one of the most frequently used keywords by authors, highlighting the swift response by communities to characterize these emerging compounds. However, it was also noted that despite drugs being a global threat, only limited international collaboration was observed between research groups and the majority of the studies are from authors affiliated within the same country. Finally, an argument is made to encourage a more comprehensive approach in aggregating results on drugs for greater transparency and broader distribution of findings.This article is categorized under: Forensic Chemistry > Mass Casualty Management Forensic Chemistry > Controlled and Emerging Drug Compounds

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“…A similar study was conducted in Brazil by da Cunha et al in 2021 [148]. The prevalence of NPS has been evaluated through the analysis of oral fluid samples collected at electronic music festivals and parties.…”

Section: Liquid Chromatographymentioning

confidence: 95%

“…In the last years, the research of new analytical methods is focusing mainly towards newly emerging designer drugs, as NBOMe and NBOH compounds. The LC-MS/MS is the most used method to identify these classes of substances [143][144][145][146][147][148][149][150][151][152]. In particular, considering the thermal lability of NBOHs, the LC-MS/MS allows to prevent their misidentification with the corresponding 2C compounds, as happened when GC-MS was used as analytical detection.…”

Section: Liquid Chromatographymentioning

confidence: 99%

Analysis of 2,5-dimethoxy-amphetamines and 2,5-dimethoxy-phenethylamines aiming their determination in biological matrices: a review

et al. 2022

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Purpose The present review aims to provide an overview of methods for the quantification of 2,5-dimethoxy-amphetamines and -phenethylamines in different biological matrices, both traditional and alternative ones. Methods A complete literature search was carried out with PubMed, Scopus and the World Wide Web using relevant keywords, e.g., designer drugs, amphetamines, phenethylamines, and biological matrices. Results Synthetic phenethylamines represent one of the largest classes of “designer drugs”, obtained through chemical structure modifications of psychoactive substances to increase their pharmacological activities. This practice is also favored by the fact that every new synthetic compound is not considered illegal by existing legislation. Generally, in a toxicological laboratory, the first monitoring of drugs of abuse is made by rapid screening tests that sometimes can occur in false positive or false negative results. To reduce evaluation errors, it is mandatory to submit the positive samples to confirmatory methods, such as gas chromatography or liquid chromatography combined to mass spectrometry, for a more specific qualitative and quantitative analysis. Conclusions This review highlights the great need for updated comprehensive analytical methods, particularly when analyzing biological matrices, both traditional and alternative ones, for the search of newly emerging designer drugs.

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Prevalence of new psychoactive substances (NPS) in Brazil based on oral fluid analysis of samples collected at electronic music festivals and parties

Cited by 18 publications

References 29 publications

Oral fluid analysis to monitor recent exposure to synthetic cannabinoids in a high‐risk subpopulation

Oral fluid analysis to monitor recent exposure to synthetic cannabinoids in a high‐risk subpopulation

Trends and challenges in the use of drugs as forensic evidence: A scientometric approach to map the current literature

Analysis of 2,5-dimethoxy-amphetamines and 2,5-dimethoxy-phenethylamines aiming their determination in biological matrices: a review

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