Prevalence of multidrug resistance genes in Escherichia coli isolates from patients attending four hospitals in Minna, Nigeria

Abstract

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Phenotypic and Molecular Detection of Resistance Genes from Multi-drug Resistant Escherichia coli Isolated from Patients Attending Selected Hospitals in Damaturu, Yobe State, Nigeria

“…The PCR amplification of resistance genes (blaTEM, accC1 and qnrA) from this study reveals that all eight (8) positive isolates shows the resistant genes (Fig 4, 5 and 6). The resistant genes obtained from this study were similar to various previous studies (Oloruntoba et al, 2020, Muhammad and Swedan, 2015, Anago et al, 2015and Machado et al, 2007. Likewise, the findings on resistant genes in this study correspond with many previous studies (Momtaz et al, 2012, Ensor et al, 2009, Robicsek et al, 2006, Hujer et al, 2006and Adebola et al, 2019.…”

“…The reports of antibiotic resistant genes found in E. coli which might indicates there is a possibility of presence of other classes of antimicrobial associated resistant genes that are not detected in this study. Therefore, there is a need for a strategies to control the rapid dissemination of these antimicrobial resistant genes through implementation of strict guidelines for counter misuse of antibiotics and also rational use of antibiotics in both human and agricultural activities and these could be the possible explanation for the emergence of multidrug resistance genes (Oloruntoba et al, 2020).…”