Objectives
To determine if there is a difference in time to initial analgesic for patients with acute pain from sickle cell disease (SCD) versus renal colic (RC) and to identify factors contributing to variance in time to analgesic.
Methods
Retrospective cohort study of adult emergency department (ED) patients with acute pain from SCD and RC in an urban ED (final ED discharge ICD-9 diagnosis codes were included). A structured medical record review abstracted demographics, arrival shift, triage level, initial pain score, triage time, and time of initial analgesic dose. Data were compared with Kaplan-Meier plots of time to initial analgesic for both RC and SCD with the log-rank test to test for differences by disease category. A multivariable Cox regression model estimated differences in time to initial analgesic by disease category while controlling for other possible confounders.
Results
Median time to initial analgesic was 80 minutes for patients with SCD (IQR, 48-145) vs. 50 minutes for patients with RC (IQR, 30-96). Patients with SCD reported a higher pain score on arrival when compared to RC patients and were more frequently assigned a higher triage priority level (p=0.05). Covariates that contributed the most delays to the model were afternoon arrival (HR 0.35, p<0.01), low priority triage level (HR 0.42, p<0.01), SCD diagnosis (HR 0.61, p<0.01), and inability to obtain intravenous access (HR 0.71, p=0.01).
Discussion
ED patients with SCD experienced longer delays to administration of the initial analgesic compared with RC patients, despite higher arrival pain scores and triage acuity levels.