Prevalence of Mild Cognitive Impairment in 60- to 64-Year-Old Community-Dwelling Individuals: The Personality and Total Health through Life 60+ Study

Abstract

This epidemiological study aimed at determining the prevalence of mild cognitive impairment (MCI) in 60- to 64-year-old individuals using different diagnostic criteria. Community dwelling individuals (n = 2,551) in the age range of 60–64 years were recruited randomly through the electoral roll. They were screened using the MMSE and a short cognitive battery, and those who screened positive underwent detailed medical and cognitive assessments. Extant MCI-related diagnoses were established by consensus. Predictive regression models on the sub-sample were used to determine population prevalence for the diagnoses. Of the 224 subjects who screened positive for MCI, 112 underwent a detailed assessment and 74% met the criteria for at least one recognised diagnosis of mild cognitive deficit (MCI and related diagnoses). By predictive regression modelling, the prevalence of any MCI diagnosis was 13.7% (95% CI 9.1–30.2) in the population of 60- to 64-year-olds. The estimated prevalence rates for specific diagnoses were: MCI 3.7%, ageing-associated cognitive decline 3.1%, Clinical Dementia Rating score (0.5) 2.8%, age-associated memory impairment 1%, other cognitive disorders 0.9%, and mild neurocognitive disorder 0.6%. Agreement on ‘caseness’ between various proposed diagnoses was at best fair and generally poor. Memory and other cognitive problems not meeting the threshold for dementia are relatively common in 60- to 64-year-old individuals living in the community. The prevalence rate varies up to six-fold according to the diagnostic criteria applied, with limited overlap between diagnoses. There is an urgent need for standardization of the criteria.

Objective and subjective memory impairment in elderly adults: a revised version of the Everyday Memory Questionnaire

“…In this study of subjective and objective measures of memory in the elderly population, to evaluate their usefulness as assessed by the EMQ and determining the best factor structure for this purpose, we found that 8.9% of elderly adults had an objective memory deficit, matching literature data reporting a prevalence between about 6% (29,30) and 15% (31). We had recruited our participants by means of a newspaper advertisement for attending a course on aging-related changes of memory, and this method may have induced a bias in sample selection, but as we found the same prevalence of memory deficits as reported in previous studies, we can assume that our sample was representative of the elderly population.…”

Funcionamiento cognitivo en personas mayores e influencia de variables socioeducativas - Resultados del Estudio ELES

“…Del total de participantes, un 3.8% cumplía criterios de sospecha de deterioro cognitivo. El nivel de prevalencia se asemejaría a los encontrados en otros estudios internacionales realizados en Estados Unidos (Ganguli et al, 2004) con valores entre 2.9-4 %, en Toscana (Tognoni et al, 2005) con una prevalencia del 4.9% y finalmente en Australia (Kumar et al, 2005) donde encuentran una prevalencia del 3.7% en personas de 60-64 años. Se ha encontrado que en los grupos de mayor nivel educativo y de personas que han ejercido profesiones de tipo no manual, la frecuencia de personas con sospecha de deterioro cognitivo es menor en comparación con aquellos con nivel educativo bajo y medio y con los que tienen o han tenido profesiones manuales.…”

Subjective Health and Memory Predictors of Mild Cognitive Disorders and Cognitive Decline in Ageing: The Personality and Total Health (PATH) through Life Study

“…The design of the Personality and Total Health (PATH) through Life Study has been described elsewhere [30]. Briefly, participants who were residents of the city of Canberra and the adjacent town of Queanbeyan, Australia, were recruited randomly through the electoral roll to participate in a study interested in the risk and protective factors for common mental disorders, normal aging and dementia.…”