Prevalence of Micronutrient Deficiency in Patients with Morbid Obesity Before Bariatric Surgery

Krzizek, Eva-Christina; Brix, Johanna; Herz, Carsten Thilo; Kopp, Hans Peter; Schernthaner, Gerit-Holger; Schernthaner, Guntram; Ludvik, Bernhard

doi:10.1007/s11695-017-2902-4

Cited by 71 publications

(65 citation statements)

References 26 publications

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“…Vitamin D deficiency defined based on the presence of low serum 25-hydroxyvitamin D (25OHD) levels is very frequent in obesity and was reported to occur in 55-97% (169,170). However, it is important to understand the mechanisms underlying the lower 25OHD levels in obesity and whether this indicates a clinically significant vitamin D deficiency.…”

Section: Reasoningmentioning

confidence: 99%

“…Thus, vitamin D deficiency to the extent that will drive an increase in bone turnover or decrease bone mineral density is clinically relevant. The prevalence of secondary hyperparathyroidism (sHPT) related to vitamin D deficiency in obesity was reported to be over 20% (169,178) and increased up to 71% depending on vitamin D status (171), while the threshold for parathyroid stimulation can be widely variable (179,180). In addition to disturbances in the vitamin D -calcium homeostasis, obesity may involve other mechanisms affecting PTH regulation that are incompletely understood.…”

Section: Reasoningmentioning

confidence: 99%

See 1 more Smart Citation

European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity

Pasquali

Casanueva

Haluzı́k

et al. 2020

European Journal of Endocrinology

127

156

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Obesity is an emerging condition, with a prevalence of ~20%. Although the simple measurement of BMI is likely a simplistic approach to obesity, BMI is easily calculated, and there are currently no data showing that more sophisticated methods are more useful to guide the endocrine work-up in obesity. An increased BMI leads to a number of hormonal changes. Additionally, concomitant hormonal diseases can be present in obesity and have to be properly diagnosed – which in turn might be more difficult due to alterations caused by body fatness itself. The present European Society of Endocrinology Clinical Guideline on the Endocrine Work-up in Obesity acknowledges the increased prevalence of many endocrine conditions in obesity. It is recommended to test all patients with obesity for thyroid function, given the high prevalence of hypothyroidism in obesity. For hypercortisolism, male hypogonadism and female gonadal dysfunction, hormonal testing is only recommended if case of clinical suspicion of an underlying endocrine disorder. The guideline underlines that weight loss in obesity should be emphasized as key to restoration of hormonal imbalances and that treatment and that the effect of treating endocrine disorders on weight loss is only modest.

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Section: Reasoningmentioning

confidence: 99%

Section: Reasoningmentioning

confidence: 99%

European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity

Pasquali

Casanueva

Haluzı́k

et al. 2020

European Journal of Endocrinology

127

156

View full text Add to dashboard Cite

show abstract

“…Several studies have observed the micronutrient deficiencies among BS candidates and reported that these patients displayed at least one vitamin or mineral baseline deficit [40,41,[49][50][51]. Table 1 presents the most common nutritional deficiencies and their prevalence documented in patients evaluated before BS.…”

Section: Micronutrient Status Of Bs Candidates: Impact On Gmmentioning

confidence: 99%

“…Micronutrient deficiencies are frequently reported after RYGB and VSG [9,51,96,97], with an incidence as great as 50% in mid-and long-term follow-ups [86]. The underlying variables associated to postoperative vitamin and mineral deficiencies are both surgery-and patient-related ( Figure 3 Micronutrient deficiencies are frequently reported after RYGB and VSG [9,51,96,97], with an incidence as great as 50% in mid-and long-term follow-ups [86]. The underlying variables associated to postoperative vitamin and mineral deficiencies are both surgery-and patient-related ( Figure 3) [98].…”

Section: Pathogenesis Of Micronutrient Deficiencies After Bsmentioning

confidence: 99%

Bariatric Surgery in Obesity: Effects on Gut Microbiota and Micronutrient Status

et al. 2020

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Obesity is associated with reduced gut microbial diversity and a high rate of micronutrient deficiency. Bariatric surgery, the therapy of choice for severe obesity, produces sustained weight loss and improvements in obesity-related comorbidities. Also, it significantly alters the gut microbiota (GM) composition and function, which might have an important impact on the micronutrient status as GM is able to synthesize certain vitamins, such as riboflavin, folate, B12, or vitamin K2. However, recent data have reported that GM is not fully restored after bariatric surgery; therefore, manipulation of GM through probiotics represents a promising therapeutic approach in bariatric patients. In this review, we discuss the latest evidence concerning the relationship between obesity, GM and micronutrients, the impact of bariatric surgery on GM in relation with micronutrients equilibrium, and the importance of the probiotics’ supplementation in obese patients submitted to surgical treatment.

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“…Furthermore, women who are obese are more likely to have children who are obese (Oestreich & Moley 2017), perpetuating health problems from generation to generation. There is evidence that obese individuals are deficient in micronutrients (Costa et al 2018;Krzizek et al 2017;Stankowiak-Kulpa et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Peer Review #3 of "Dietary diversity is inversely correlated with pre-pregnancy body mass index among women in a Michigan pregnancy cohort (v0.1)"

2018

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Background. During pregnancy, healthy maternal body weight and a nutritionally complete diet provide a favorable environment for fetal development. Yet nearly twothirds of women of reproductive age in the United States (US) are either overweight or obese. The objective of this research was to investigate the relationship between a measure of dietary diversity and body mass index (BMI) in a sample of women enrolled in a US pregnancy cohort. Methods. Dietary data was obtained from one 24-hour dietary recall collected during the third trimester of pregnancy (n=40). Pre-pregnancy BMI was calculated from pre-pregnancy weight and height self-reported by survey at the time of enrollment. Using the Minimum Dietary Diversity for Women (MDD-W) indicator developed by the Food and Agriculture Organization of the United Nations, dietary data was categorized and scored. Results. Overall, 35% of participants did not achieve minimum dietary diversity (MDD-W ≥5). In addition, 45% of participants were obese, 35% were normal weight and 20% were overweight. Women with higher BMI had lower MDD-W scores than women with lower BMI (p<0.05). The median MDD-W for both normal and overweight women was ≥5 indicating that normal and overweight pregnant women tended to consume a diet that was high in micronutrients. Conversely, the median MDD-W for obese women was below 5 meaning these women tended to consume a diet that was low in micronutrient density. The most commonly consumed food group was grain. In addition, 75% of all participants consumed sweetened drinks. Individuals with an MDD-W score ≥5, were more likely to have consumed dark green leafy vegetables, vitamin A-rich fruits or vegetables, other vegetables and other fruits than those with MDD-W scores <5. Discussion. In this study, we show that a food group diversity indicator that has been shown to reflect adequacy of micronutrient intake in populations from less economically developed countries may also be informative in US populations. Furthermore, these results reflect the importance of encouraging all pregnant women with less varied diets to consume more fruits and vegetables.

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Prevalence of Micronutrient Deficiency in Patients with Morbid Obesity Before Bariatric Surgery

Abstract: Our data show a high prevalence of micronutrient deficiency in patients with morbid obesity preoperatively and emphasize the importance of exact preoperative evaluation and adequate substitution as well as postoperative surveillance.

Cited by 71 publications

References 26 publications

European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity

European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity

Bariatric Surgery in Obesity: Effects on Gut Microbiota and Micronutrient Status

Peer Review #3 of "Dietary diversity is inversely correlated with pre-pregnancy body mass index among women in a Michigan pregnancy cohort (v0.1)"

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