Prevalence of microalbuminuria in a selected South Indian population - the Chennai Urban Population Study (CUPS)

Morbidity Profile and Causes of Mortality in Type 2 Diabetes Patients: Data from a Tertiary Teaching Hospital from Eastern India

“…Das et al reported the age at the time of death for people with DM to be 55 -61 years and that mortality among hospitalized patients with non-insulin-dependent DM was nearly 20%, which is comparable with the findings of present study [7]. A recent population based study from South India by Mohan et al reported the mean age of death to be 66 years and mortality related to diabetic complications to be 11.9% [6]. Analysing the causes of mortality in our cohort it was found that CVD (36.4%) was the most common cause of death followed by infection (27.3%), CAD (15.1%), CKD (12.1%), and HHS (9.0%).…”

“…Cardiovascular (CV) related death (which includes CAD and CVD) was by far the most common cause of death in our series accounting for more than half (51.5%) of total death which could be due to the fact that macrovascular complications occured earlier than microvascular complications. Mohan et al also had similar observations from South India, reported CV related deaths was the most common etiology, accounting for mortality in nearly 53% cases [6]. Das et al…”

“…The study also reported that the prevalence of mortality due to cardio vascular disease (diabetic subjects: 52.9%, non-diabetic subjects: 24.2%, P = 0.042) followed by renal disease (diabetic subjects: 23.5%, non-diabetic subjects: 6.1%, P = 0.072) was higher among diabetic subjects compared to non-diabetic counterparts [6]. A study from a tertiary care hospital of Odisha in 1991 had revealed the mortality pattern in DM patients as follows: chronic kidney disease (CKD) 35%, infection 33.7%, cerebrovascular disease (CVD) 32.5%, CAD 30% and diabetic coma 20.2% respectively [7].…”

“…Bhansali et al also reported a prevalence of 9.4% of CKD related death [42]. Mohan et al from South India reported CKD related death to be 23.5% [6]. This could be due to poor glycemic control, inadequate facility for renal replacement therapy (RRT) like dialysis/transplant, and lack of affordability to RRT.…”

“…According to the CUPS-16, the overall mortality was nearly 2-fold higher in diabetic subjects compared to non-diabetic cohorts (18.9 vs. 5.3 per thousand person years, P = 0.004) [6]. The study also reported that the prevalence of mortality due to cardio vascular disease (diabetic subjects: 52.9%, non-diabetic subjects: 24.2%, P = 0.042) followed by renal disease (diabetic subjects: 23.5%, non-diabetic subjects: 6.1%, P = 0.072) was higher among diabetic subjects compared to non-diabetic counterparts [6].…”