Prevalence of Microalbuminuria Among Patients with Type 2 Diabetes Mellitus—A Hospital-Based Study from North India

Kanakamani, J; Ammini, AC; Gupta, Nandita; Dwivedi, S

doi:10.1089/dia.2009.0133

Cited by 30 publications

(31 citation statements)

References 23 publications

(34 reference statements)

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“…Similar results were obtained in study done by Hetal Pandya et al, Ram Vinod Mahato et al and Prashant Tayde et al 4,6,7 In our study prevalence of Diabetic Nephropathy was 41 %, micro albuminuria was present in 25 % patients and 16% had macro albuminuria. Similar results were obtained in studies done by Mohammed Ahmed Bamashmoos Krairittichai U, et al, Kanakamani J, et al [8][9][10] Out of 59 patients with normal AER, 30.5 % patients had GFR < 90 ml/min/1.73m 2 whereas rest of the patients had GFR > 90ml/min/1.73 m 2 . Study done by Macisaac RJ and Jerums G has shown that 20 % patients with type 2 diabetes have GFR <60ml/min/1.73m 2 while remaining normo albuminuric.…”

Section: Discussionsupporting

confidence: 87%

Study of serum lipid profile in type 2 diabetes mellitus patients and its association with diabetic nephropathy

Kolhar

Priyanka

2017

Int J Adv Med

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Background: Dyslipidaemia is highly prevalent in type 2 Diabetes mellitus patients. The role of dyslipidaemia in macrovascular complications of Diabetes have been extensively studied but its role in microvascular complications namely nephropathy is still unclear. The present study was undertaken to study the prevalence and pattern of dyslipidaemia and its association with Diabetic nephropathy (DN) in patients with type 2 DM.Methods: 100 patients with type 2 DM attending OPD or admitted, over a period of 1 year were studied. Detailed history was taken and clinical examination was done. Serum lipid profile was studied in all patients and its association with DN was assessed.Results: The prevalence of dyslipidaemia in DM patients in our study was 90% and there was no statistically significant difference in the prevalence among males and females. Poorly controlled diabetics had high prevalence of dyslipidaemia as compared to well controlled diabetics. The prevalence of Diabetic nephropathy in our study was 41%. There was significant association of DN with high Total Cholesterol, high Low-density lipoprotein (LDL-C) and high Triglycerides. There was no significant association of DN with High density lipoprotein (HDL-C).Conclusions: Present study highlights the magnitude of dyslipidaemia in type2 DM patients and that there is a significant association of DN with lipid parameters. Hence patients should be managed with life style modifications with or without lipid lowering agents to achieve target lipid values along with adequate glycemic control to prevent or delay the appearance and progression of DN.

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Section: Discussionsupporting

confidence: 87%

Study of serum lipid profile in type 2 diabetes mellitus patients and its association with diabetic nephropathy

Kolhar

Priyanka

2017

Int J Adv Med

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“…Mean age of patients with diabetes in the present study was 50.57 years, which is similar to that, reported by Chowta et al 6 , Kanakmani et al 12 and Maskari et al 13 whereas, in the studies of Tandon et al 8 the patients belonged to a younger age group with mean age of 52.2 years. Generally, diabetic nephropathy affects both males and females equally.…”

Section: Results:-supporting

confidence: 89%

Correlation Between Microalbuminuria and Hba1c Among Type2 Diabetic Patients in Jammu, J and K State, India.

Raina¹,

Gupta²,

Sheikh³

et al. 2018

IJAR

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“…The search for reliable urinary markers predicting DN has been ample as reflected by a recent study by Kanakamani et al, which assessed 670 patients with DM and CKD [55]. It utilized urinalysis to evaluate the predictive role of microalbuminuria in DN patients [55].…”

Section: Urinary Markersmentioning

confidence: 99%

“…It utilized urinalysis to evaluate the predictive role of microalbuminuria in DN patients [55]. It showed no statistically significant correlation between the median diabetic duration and the prevalence of microalbuminuria, as reflected by microalbuminuria prevalence being 25.5% (95% confidence interval (CI), 22.4-29%) and 24.7% in those with median diabetic duration of 5 years and DM of < 1 year, respectively [55].…”

Section: Urinary Markersmentioning

confidence: 99%

Predictors of diabetic nephropathy

Gaballa

Farag

2013

Open Medicine

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AbstractDiabetic nephropathy (DN) is a leading cause of morbidity and mortality in diabetic patients representing a huge health and economic burden. Alarming recent data described diabetes as an unprecedented worldwide epidemic, with a prevalence of ∼6.4% of the world population in 2010, while the prevalence of CKD among diabetics was approximately 40%. With a clinical field hungry for novel markers predicting DN, several clinical and laboratory markers were identified lately with the promise of reliable DN prediction. Among those are age, gender, hypertension, smoking, sex hormones and anemia. In addition, eccentric left ventricular geometric patterns, detected by echocardiography, and renal hypertrophy, revealed by ultrasonography, are promising new markers predicting DN development. Serum and urinary markers are still invaluable elements, including serum uric acid, microalbuminuria, macroalbuminuria, urinary liver-type fatty acid-binding protein (u-LFABP), and urinary nephrin. Moreover, studies have illustrated a tight relationship between obstructive sleep apnea and the development of DN. The purpose of this review is to present the latest advances in identifying promising predictors to DN, which will help guide the future research questions in this field. Aiming at limiting this paramount threat, further efforts are necessary to identify and control independent modifiable risk factors, while developing an integrative algorithm for utilization in DN future screening programs.

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Prevalence of Microalbuminuria Among Patients with Type 2 Diabetes Mellitus—A Hospital-Based Study from North India

Cited by 30 publications

References 23 publications

Study of serum lipid profile in type 2 diabetes mellitus patients and its association with diabetic nephropathy

Study of serum lipid profile in type 2 diabetes mellitus patients and its association with diabetic nephropathy

Correlation Between Microalbuminuria and Hba1c Among Type2 Diabetic Patients in Jammu, J and K State, India.

Predictors of diabetic nephropathy

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