Prevalence of methicillin-resistant Staphylococcus aureus colonization in surgical patients, on admission to a Welsh hospital

Community-acquired methicillin-resistant Staphylococcus aureus: Epidemiology and potential virulence factors

“…While acknowledging that some MRSA strains may have arisen in the community, the authors concluded that the increase of community-onset MRSA in the community is largely caused by "exporting" of strains as patients are discharged from the hospital. Several other studies published since that meta-analysis similarly have found a high prevalence of nosocomial risk factors in MRSA-colonized community-dwelling patients or their household contacts [20,[37][38][39][40]. Also supportive are the findings of a Swiss national survey of MRSA isolates, which determined that patients colonized with a sporadic strain were more likely than patients with predominant nosocomial strains to have been transferred from a foreign hospital [41].…”

Genetic Lineages of Methicillin-Resistant Staphylococcus aureus Acquired during Admission to an Intensive Care Unit of a General Hospital

“…The 0.74% prevalence of MRSA among patients at the time of admission to the ICU in this study was comparable to an earlier study from our geographical region (Saudi Arabia) that reported prevalence of MRSA colonization at the time of admission to be 1.1% [23] . However, other studies have shown different prevalence rates of MRSA colonizing patients at the time of admission to ICU, which ranged from 2.5 to 46% [10,[24][25][26] , probably reflecting a higher rate of MRSA colonization in the community prior to hospital admission. However, a study from Brazil which reported a higher frequency (46%) of colonization with MRSA at the time of admission with 52% of the patients acquiring it in the ICU, did not find any association with identifiable risk factors although the unusually higher rates of MRSA acquisition among their patient population in the ICU was attributed to improper hand-washing, environmental surface cleaning, and barrier protection from infected patients, unlike infection control procedures adopted in our ICU [26] .…”

“…treatment [10] . Some of the important risk factors for acquisition and colonization of MRSA are use of extendedspectrum antimicrobial agents [4] and prolonged duration of antimicrobial therapy [3] , whereas inappropriate antimicrobial therapy, comorbid conditions, and advanced patient age cause increased mortality associated with systemic MRSA infections [5] .…”

Anti-VRE and Anti-MRSA Activities of New Quinolones and Their Synergism with Commercial Antibiotics. Part 2

“…On the other hand, during the past two decades, methicillin resistant Staphylococcus aureus (MRSA) has become an increasingly common microorganism in hospitals (Voss et al, 1994;Coolson, 1995;Cox et al, 1995;Working Party Report, 1998;Kotilainen et al, 2001;Kron et al, 2002;Samad et al, 2002;Shiojima et al, 2003;Burd et al, 2003;De LucasVillarrubia et al, 2003;Ellis et al, 2003;Jarvis et al, 2007;Millar et al, 2008). Thus, eradication of MRSA infection is becoming another serious target in clinical scenes worldwide.…”