Prevalence of metabolic syndrome in Iranian patients with schizophrenia: A systematic review and meta-analysis

Shojaeimotlagh, Vahid; Hashiehbaf, Atieh; Karami, Maryam; Monjazebi, Fateme; Gheshlagh, Reza Ghanei

doi:10.1016/j.dsx.2018.08.014

Cited by 19 publications

(15 citation statements)

References 26 publications

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“…In this study, class I obesity or higher, defined as a body mass index of 25 kg/m 2 or higher, was remarkably common (76.2%) among the participants with metabolic syndrome, which supports findings from previous studies suggesting that a high body mass index increases the risk of metabolic syndrome [ 3 , 37 ]. Body mass index is a key indicator of metabolic syndrome, and it is easily measurable and readily quantifiable [ 39 ].…”

Section: Discussionsupporting

confidence: 90%

“…Compared to the results of those two studies, the prevalence of metabolic syndrome among these community-dwelling schizophrenia patients was twice as high as that of the general population. Furthermore, the prevalence observed in this study was higher than has been observed in Japan (34.2%) [ 36 ], Taiwan (37.8%) [ 37 ], and Iran (23.9%) [ 38 ], which confirms the need for proactive management of metabolic syndrome in people with schizophrenia in Korea. Therefore, mental health care nurses who manage the health of people with schizophrenia living in the community need to recognize the high prevalence of metabolic syndrome among their patients and implement regular education and management.…”

Section: Discussionsupporting

confidence: 67%

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Risk Factors of Metabolic Syndrome in Community-Dwelling People with Schizophrenia

Sun

Jang

2020

IJERPH

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This study investigated the prevalence and risk factors of metabolic syndrome in 100 community-dwelling people with schizophrenia registered in mental health facilities in Seoul, Korea. This study was conducted between 12 September and 15 November 2019. This study used a cross-sectional descriptive design. The data included were general and disease-related characteristics, diagnostic tests for metabolic syndrome, lifestyles, depression, and social support. The analysis of collected data was done by using the SPSS 24.0 program. The prevalence of metabolic syndrome was 42.0%. Higher body mass index (odds ratio [OR] = 1.60, 95% CI = 1.16–2.18, p = 0.004), and depression (OR = 1.22, 95% CI = 1.06–1.42, p = 0.008) were associated with higher risks of metabolic syndrome, while physical activity and weight control (OR = 0.71, 95% CI = 0.54–0.94, p = 0.018), dietary habits (OR = 0.72, 95% CI = 0.54–0.93, p = 0.011), and medication and health management (OR = 0.52, 95% CI = 0.31–0.86, p = 0.012) were associated with lower risks. Mental health care nurses need to recognize the high prevalence of metabolic syndrome in people with schizophrenia in the community and provide differentiated, customized lifestyle improvement programs based on the body mass index and depression status of each person with schizophrenia. Furthermore, comprehensive lifestyle improvement programs and health examination services that people with schizophrenia can easily adhere to should be developed.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 67%

Risk Factors of Metabolic Syndrome in Community-Dwelling People with Schizophrenia

Sun

Jang

2020

IJERPH

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“…Schizophrenia, a severe mental disorder, is characterized by neurological, behavioral and emotional changes. The disease affects 1% of the world population, mainly individuals under 25 years of age (Kim et al, 2015;Pinheiro et al, 2017;Shojaeimotlagh et al, 2019). Genetic, environmental and metabolic factors have been associated with this disorder (Boskovic et al, 2011;Emiliani et al, 2014;Mak et al, 2019;Shojaeimotlagh et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Research Article Genetic and biochemical biomarkers related to oxidative stress in patients with schizophrenia

Forner¹,

Andreguetto²,

Lopes³

et al. 2019

Genet. Mol. Res.

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We evaluated the association of glutathione Stransferase polymorphisms (GSTT1 and GSTM1) and oxidative stress biomarkers in patients with schizophrenia. A total of 162 subjects were studied: 53 had schizophrenia (Total Study Group-TSG), and 109 without the disorder (Total Control Group-TCG). To analyze oxidative stress, TSG was distributed into treatment-responsive schizophrenia (N = 26) and treatment-resistant (N = 27) versus

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“…), female gender (Shojaeimotlagh et al . ), being married (Grover et al . ), and prolonged illness (Mitchell et al .…”

Section: Introductionmentioning

confidence: 99%

“…Numerous sociodemographic factors contribute to MetS among patients with serious mental illness, such as old age (Mitchell et al 2013;Vancampfort et al 2013), female gender (Shojaeimotlagh et al 2019), being married , and prolonged illness (Mitchell et al 2013). In addition, MetS risk is higher in patients taking prescribed antipsychotic medication (Mitchell et al 2013;Vancampfort et al 2014;Vancampfort et al 2013), particularly in patients receive three or more psychotropic medications (Severi et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Gender differences in metabolic syndrome risk factors among patients with serious mental illness

Tzeng

Chiang

Feng

et al. 2019

Int J Mental Health Nurs

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The prevalence of metabolic syndrome and its components continue to increase among patients with serious mental illness. This cross‐sectional study investigated whether metabolic syndrome prevalence and risk factors differ between male and female patients with serious mental illness. In total, 260 eligible patients were recruited from two hospitals. The data on demographic characteristics, lifestyle behaviour factors, biochemistry, and anthropometry were collected. Analyses were performed using multivariate logistic regression. Metabolic syndrome prevalence was 40.8% (35.1% in men and 46.8% in women). Among patients aged 40–49 years, metabolic syndrome prevalence was higher in men; however, the trend was reversed among patients aged 50 years or older. Notably, gender‐specific metabolic syndrome risk factors were observed. In men, they included low education level, high body mass index (BMI), prolonged illness, comorbid physical illness, and diagnosis of bipolar disorder, whereas they included being married, old age, and high BMI in women. Our findings suggest that mental health professionals should consider the gender‐ and age‐based metabolic syndrome prevalence trend in patients with serious mental illness when designing interventions for the study population to minimize metabolic syndrome prevalence.

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Prevalence of metabolic syndrome in Iranian patients with schizophrenia: A systematic review and meta-analysis

Cited by 19 publications

References 26 publications

Risk Factors of Metabolic Syndrome in Community-Dwelling People with Schizophrenia

Risk Factors of Metabolic Syndrome in Community-Dwelling People with Schizophrenia

Research Article Genetic and biochemical biomarkers related to oxidative stress in patients with schizophrenia

Gender differences in metabolic syndrome risk factors among patients with serious mental illness

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