Prevalence of metabolic syndrome in hypothyroidism: Experience in a tertiary center in South India

Khare, Jaideep; Nalla, Smitha; Wadhwa, Jyoti; Reddy, Babul; Deb, Prasun

doi:10.4103/2348-3334.196035

Cited by 3 publications

(3 citation statements)

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“…In general, the prevalence of MS is higher among those with hypothyroidism compared to thyrotoxicosis. [17][18][19][20] These findings are supported by a study in Nepal looking at the prevalence of thyroid dysfunction among 169 adults diagnosed with MS by the NCEP/ATP III criteria where 26.6% have subclinical hypothyroidism, 3.5% have overt hypothyroidism, in contrast to only 1.7% having subclinical hyperthyroidism. 20 In the Philippines, the Philippine Thyroid Diseases Study (PhilTiDeS 1) showed that thyroid dysfunction was more common among women.…”

Section: Methodology Patients and Proceduresmentioning

confidence: 63%

“… 13 In the Philippines, the prevalence of MS in the general population ranges from 11.9% to 51.0% depending on the criteria used. 12 , 14 , 15 Likewise, the prevalence of MS in hypothyroidism varies depending on the population: 36.19% in a recent retrospective cross-sectional local study in the Philippine General Hospital, Manila, Philippines, 16 40.0% in Nigeria, 17 53.24% in Southern India 18 and 51.8% in Venezuela 19 . In general, the prevalence of MS is higher among those with hypothyroidism compared to thyrotoxicosis.…”

Section: Introductionmentioning

confidence: 99%

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Characteristics and Prevalence of Metabolic Syndrome among Adult Filipinos with Hypothyroidism: A Cross-sectional Study

Chiu,

Villanueva,

Larrazabal

et al. 2024

JAFES

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Objectives. We determined the clinical characteristics and prevalence of metabolic syndrome among adult Filipinos with overt hypothyroidism. Methodology. This is a cross-sectional study of 151 adults. Patients were recruited by sequential enrollment. Anthropometric and blood pressure measurements were performed followed by blood extraction for metabolic parameters and thyroid function tests. Clinical and laboratory characteristics were compared between patients with and without metabolic syndrome.Results. The prevalence of metabolic syndrome is 40.4% (95%CI: 32.5%, 48.7%). Patients with metabolic syndrome have a waist circumference of 88.4 ± 7.7 cm in females and 93.3 ± 9.0 cm in males. The median fasting blood glucose was 111.4 (52.2) mg/dL, median systolic blood pressure of 120 (30) mm Hg and diastolic blood pressure of 80 (20) mmHg, median serum triglycerides of 174.3 (114.2) mg/dL, median HDL-C of 42.3 (19.2) mg/dL and a proportion of patients with diabetes (23.0%) and hypertension (44.3%), respectively. The presence of increased waist circumference is the most prevalent component seen among hypothyroid patients. There were no differences in terms of age, sex, etiology of hypothyroidism and anti-TPO levels in those with and without metabolic syndrome.Conclusion. The prevalence of metabolic syndrome in adult Filipinos with hypothyroidism is high. Emphasis must be placed on early screening using waist circumference and metabolic parameters among hypothyroid patients who are at high risk of developing metabolic syndrome

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Section: Methodology Patients and Proceduresmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Characteristics and Prevalence of Metabolic Syndrome among Adult Filipinos with Hypothyroidism: A Cross-sectional Study

Chiu,

Villanueva,

Larrazabal

et al. 2024

JAFES

View full text Add to dashboard Cite

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“…En el mismo año, Bamashmos y Atef realizaron un estudio en Yemen en el que buscaron la prevalencia del SM y sus componentes en pacientes con hipotiroidismo; encontraron SM en el 37% de los que tienen hipotiroidismo, siendo más alto en pacientes con hipotiroidismo subclínico (76%) (se usaron los criterios del Programa Nacional de Educación sobre el Colesterol y el III Panel de Tratamiento del Adulto [NCEP:ATPIII]) 13 . El siguiente año, Jaideep Khare y otros investigadores en la India realizaron el mismo estudio pero en su población, encontrando una prevalencia del 53% por los criterios del NCEP:ATP III, siendo la obesidad central el criterio más encontrado 14 . Mientras que en 2018, Mumtaz y Muhammed realizaron un estudio similar, buscando prevalencia de SM en pacientes hipotiroideos bajo tratamiento con levotiroxina (con los criterios de la IDF) y encontraron un 52% de SM en pacientes hipotiroideos, además de una relación positiva entre la dosis de levotiroxina y el perímetro abdominal, índice de masa corporal (IMC) y niveles de colesterol ligado a lipoproteínas de baja densidad 15 .…”

Section: Introductionunclassified

Síndrome metabólico en pacientes mexicanos con hipotiroidismo

Mendoza-Romo¹,

Ponce-Muñiz²,

Escudero-Lourdes³

et al. 2021

RME

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Objetivo: Determinar la prevalencia del síndrome metabólico en pacientes mexicanos con hipotiroidismo. Métodos: Se seleccionó una muestra de 293 pacientes con diagnóstico de hipotiroidismo durante un lapso de seis meses. Se analizó el perfil de lípidos, el perfil tiroideo, la glucosa en ayuno, la presión arterial, el peso, la talla y el perímetro abdominal. Se tomaron los criterios de la Federación Internacional de Diabetes para el diagnóstico de síndrome metabólico. Resultados: Del total de pacientes estudiados, un 12% (35) fueron hombres y un 88% (258) mujeres, se encontró el 65% (190) con síndrome metabólico, el cual fue mayor en aquellos con hipotiroidismo subclínico, 76% (60), que en hipotiroidismo clínico, 60% (130). Los componentes más frecuentemente encontrados en los pacientes estudiados fueron niveles bajos de colesterol ligado a lipoproteínas de alta densidad en el 82% (240) y obesidad central en el 77% (226). Conclusiones: Existe una mayor presencia de síndrome metabólico en pacientes con hipotiroidismo, sobre todo en aquellos con hipotiroidismo subclínico, por lo que se sugiere una búsqueda de ambas enfermedades para un adecuado manejo y control del riesgo cardiovascular.

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Zulewski's clinical score and its validation in hypothyroid patients: Experience in a tertiary care center in Western India

Khare¹,

Rai

Ghanekar

2020

CHRISMED J Health Res

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Prevalence of metabolic syndrome in hypothyroidism: Experience in a tertiary center in South India

Cited by 3 publications

References 1 publication

Characteristics and Prevalence of Metabolic Syndrome among Adult Filipinos with Hypothyroidism: A Cross-sectional Study

Characteristics and Prevalence of Metabolic Syndrome among Adult Filipinos with Hypothyroidism: A Cross-sectional Study

Síndrome metabólico en pacientes mexicanos con hipotiroidismo

Zulewski's clinical score and its validation in hypothyroid patients: Experience in a tertiary care center in Western India

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