Prevalence of metabolic syndrome among breast cancer survivors in East Coast of Peninsular Malaysia

Abstract

Background To date, limited data are available on metabolic syndrome prevalence among breast cancer survivors in Malaysia. Therefore, this study was conducted to determine the prevalence of metabolic syndrome and abnormal metabolic syndrome components among breast cancer survivors in East Coast of Peninsular Malaysia. Methods This cross-sectional study included 95 breast cancer survivors (age 53.7 ± 7.6 years) who have completed main cancer treatments for ≥6 months. Cancer survivors were recruited from two main government hospitals in Kelantan and Terengganu using a purposive sampling method. Results According to the Harmonized criteria, the metabolic syndrome prevalence was 50.5%. Among those with metabolic syndrome, the most prevalent abnormal metabolic components were triglycerides (91.2%), fasting blood glucose (79.6%) and HDL-c level (78.4%). Except for total cholesterol and LDL-c, all other metabolic syndrome components were significantly different (p < 0.05) between those with and without metabolic syndrome. Significant differences between metabolic syndrome and non-metabolic syndrome groups were found for weight, BMI, waist circumference, body fat percentage and cancer stages (p < 0.05). However, no significant relationship was reported between sociodemographic, clinical parameters and metabolic syndrome among breast cancer survivors in this study. Conclusions Metabolic syndrome was highly prevalent among breast cancer survivors. It is recommended for health care professionals to closely monitor and improve the triglycerides, blood glucose and HDL-c level of the breast cancer survivors under their care to control the detrimental effect of metabolic syndrome.

Relationship Between Handgrip Strength and Metabolic Syndrome Among Middle-Aged and Elderly Cancer Survivors

“…The same study also reported that the risk of metabolic syndrome among cancer survivors is increased because of changes in metabolic system and a deficiency of growth hormone following cancer treatment including radiation therapy. There has been a recent study on the prevalence of metabolic syndrome according to cancer stage 45 . However, even though there are a few studies on the prevalence of metabolic syndrome according to the survival stage of cancer survivors, 46 further studies on metabolic syndrome focused on survival stage of cancer survivors are recommended.…”

“…There has been a recent study on the prevalence of metabolic syndrome according to cancer stage. 45 However, even though there are a few studies on the prevalence of metabolic syndrome according to the survival stage of cancer survivors, 46 further studies on metabolic syndrome focused on survival stage of cancer survivors are recommended.…”

Efeitos do treinamento resistido sobre indicadores de saúde de sobreviventes de câncer de mama

“…No que diz respeito aos aspectos bioquímicos, já está bem estabelecido que os desequilíbrios lipídicos são peça-chave no desenvolvimento de síndrome metabólica 7 e doenças cardiovasculares em SCMs 10 . Atentos a isso, Abbasi et al 27 investigaram recentemente os efeitos do exercício físico sobre o perfil lipídico de pacientes de CM, mas constataram que os treinamentos empregados foram incapazes de gerar benefícios sobre t-C, TGC, HDL-C e LDL-C. Já no modelo de 12 semanas de TRNL utilizado no presente estudo, obtevese aumento significante de HDL-C, que é uma lipoproteína fundamental no transporte reverso de colesterol 28 ; e diminuição nos níveis de t-C, t-C/HDL-C, LDL-L, LDL-C/HDL-C, VLDL-C e TGC.…”

“…Em razão da doença em si e dos tratamentos utilizados, essas mulheres costumam lidar com efeitos colaterais locais e sistêmicos em curto, médio e longo prazo 3,5 . Dentre outros agravos, as SCMs estão sujeitas à fadiga excessiva e redução da aptidão física 3,5 , prejuízos sobre características antropométricas 6 , síndrome metabólica 7 e alterações de composição da membrana celular 8 . Ademais, se comparadas com mulheres sem histórico de câncer, as SCMs demonstram maior risco de depressão 9 e de mortalidade por doenças cardiovasculares 10 .…”