Prevalence of Laryngeal Irritation Signs Associated with Reflux in Asymptomatic Volunteers: Impact of Endoscopic Technique (Rigid vs. Flexible Laryngoscope)

Milstein, Claudio F.; Charbel, Samer; Hicks, Douglas M.; Abelson, Tom I.; Richter, Joel E.; Vaezi, Michael F.

doi:10.1097/01.mlg.0000184325.44968.b1

Cited by 158 publications

(115 citation statements)

References 13 publications

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“…Moreover, there was no significant difference between the positive and negative pH groups for RFS scores. These results match some other studies that reported the presence of LPR-related laryngeal signs in healthy volunteers with no voice problems [21,29,30,31,32,33,34,35]. The results of these studies indicate that most of the laryngoscopic findings reported in LPR patients are nonspecific and the laryngoscopic diagnosis of LPR is more likely subjective.…”

Section: Discussionsupporting

confidence: 77%

Voice Problems among Laryngopharyngeal Reflux Patients Diagnosed with Oropharyngeal pH Monitoring

Mesallam

Malki²,

Farahat³

et al. 2013

Folia Phoniatr Logop

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Background and Objectives: There is a lack of consensus regarding the clinical presentation and diagnosis of laryngopharyngeal reflux (LPR). The aim of this study was to explore voice-related abnormalities in a group of LPR patients, diagnosed with a 24-hour oropharyngeal pH monitoring. Patients and Methods: Eighty-two patients with voice-related problems participated in the study. Diagnosis of LPR was made using a 24-hour oropharyngeal pH monitoring. Patients were divided accordingly into positive and negative pH groups. Comparisons between the two groups were done, including results of clinical presentation, Voice Handicap Index-10 (VHI-10), reflux symptom index (RSI), reflux finding score (RFS), and acoustic measurements. The correlation was conducted between Ryan scores and other variables including VHI-10, RSI, and RFS. Results: Significant differences were found between the two groups for RSI and VHI-10. No significant differences were found between the two groups regarding clinical presentation, RFS or acoustic measures. Significant positive correlations were found between the Ryan composite measurements and both severity ratings (VHI-10, RSI). Conclusion: LPR clinical presentation appears to be non-specific in terms of symptoms and laryngeal findings. LPR appears to have an effect on the patients' self-perception of voice problems. Further studies are needed to clarify the effect of LPR on acoustic measurements.

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Section: Discussionsupporting

confidence: 77%

Voice Problems among Laryngopharyngeal Reflux Patients Diagnosed with Oropharyngeal pH Monitoring

Mesallam

Malki²,

Farahat³

et al. 2013

Folia Phoniatr Logop

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“…Laryngoscopic fi ndings, especially edema and erythema, are oft en used to diagnose refl ux-induced laryngitis ( 134 ). It should be pointed out that laryngoscopy revealed one or more signs of laryngeal irritation in over 80 % of healthy controls in a well-done prospective study ( 135 ). Moreover, in a study of fi ve ENT (ear, nose, and throat) physicians who blindly evaluated 120 video recordings of laryngoscopy exams, concordance among physicians was low for edema, erythema, as well as likelihood and severity of laryngopharyngeal refl ux; similarly, intra-rater reliability was extremely variable for these fi ndings ( 136 ).…”

Section: Gerd Refractory To Treatment With Ppismentioning

confidence: 99%

Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease

Katz¹,

Gerson²,

Vela³

2013

American Journal of Gastroenterology

1,533

1,430

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“…The comparison of findings between flexible and rigid laryngoscopes on healthy volunteers, laryngeal signs such as arytenoid erythema and pseudosulcus were more like- Table 5. Relation between the reflux symptom index and individual variables from the reflux finding score ly to be detected with a flexible rather than a rigid endoscope (23). For this reason, reliability of RFS with flexible laryngoscope should also be investigated with future studies.…”

Section: Discussionmentioning

confidence: 99%

The Reflux Finding Score: Reliability and Correlation to the Reflux Symptom Index

Karakaya¹,

Akbulut²,

Altintaş³

et al. 2015

JAREM

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Objective: To evaluate the correlation between the reflux symptom index (RSI) and the reflux finding score (RFS) in the patients with voice-related problems and to investigate the reliability of RFS.Methods: Fifty-four patients presenting with the complaint of voice abnormality were included in the study. Patients were asked to complete an RSI score sheet, and they were examined by rigid laryngostroboscopy. Laryngostroboscopic examinations of the patients were evaluated and rated with RFS by three different otolaryngologists blinded to patient information in two different sessions to evaluate intra-rater and inter-rater reliability. The correlations between RSI and RFS, for both total RFS and individual variables from RFS, were investigated.Results: Sixty-three percent were female and 37% were male, with a mean±SD age of 39.09±14.43 years. RSI ranged from 4 to 31, and RFS ranged from 8 to 22. All three raters demonstrated highly consistent intra-rater and inter-rater reliability for both total RFS and individual variables from RFS. There was a highly significant statistical correlation between RSI and total RFS (r=0.696; p=0.0001). Individual variables from RFS, except the posterior commissure hypertrophy, also demonstrated a significant positive correlation with RSI scores (p<0.05).Conclusion: RFS is a simple scale that could easily be administered with high intra-rater and inter-rater reliability for the evaluation of laryngopharyngeal reflux. RSI is highly correlated with both total RFS and all the individual variables from RFS, except posterior commissure hypertrophy. (JAREM 2015; 5: 68-74)

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Prevalence of Laryngeal Irritation Signs Associated with Reflux in Asymptomatic Volunteers: Impact of Endoscopic Technique (Rigid vs. Flexible Laryngoscope)

Cited by 158 publications

References 13 publications

Voice Problems among Laryngopharyngeal Reflux Patients Diagnosed with Oropharyngeal pH Monitoring

Voice Problems among Laryngopharyngeal Reflux Patients Diagnosed with Oropharyngeal pH Monitoring

Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease

The Reflux Finding Score: Reliability and Correlation to the Reflux Symptom Index

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