Prevalence of Iron Deficiency in Thalassemia Trait: A study in BSMMU, Dhaka

Rahman, Mustafizur; Irshadullah, Naseeb Muhammad; Ahmed, M. S.; Kabir, Amin Lutful; Begum, Mahmuda; Mostafa, Abm Golam; Khan, Anisur Rahman

doi:10.3329/bjmed.v25i1.25072

Cited by 5 publications

(6 citation statements)

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“…There were hardly any cases with ID (infection-adjusted ferritin<12 ng/mL), unlike the observed co-existence of ID and thalassemia traits in other studies. 8 , 25 The lack of ID in the subjects can be plausibly explained by the iron from groundwater; and not accounted for dietary iron, which was suboptimum relative to the requirement in this age-group. 22…”

Section: Discussionmentioning

confidence: 85%

“…5,7 There were hardly any cases with ID (infection-adjusted ferritin<12 ng/mL), unlike the observed co-existence of ID and thalassemia traits in other studies. 8,25 The lack of ID in the subjects can be plausibly explained by the iron from groundwater; and not accounted for dietary iron, which was suboptimum relative to the requirement in this age-group. 22 In Bangladesh, there is a national policy for control of childhood anemia with the provision of the blanket iron supplementation in combination of other micronutrients that is, micronutrient powder (MNP) formulation containing 12.5 mg iron per dose.…”

Section: Discussionmentioning

confidence: 88%

“…3 , 4 Hence, a few guidelines suggest the avoidance of routine supplementation of iron, unless there is a deficiency of iron. 5 , 6 However, in the developing country settings where dietary iron is sparse and predominantly plant-based, often a coexistence of thalassemia carriers and iron deficiency anemia is reported, 7 , 8 which warrants a correction by iron supplementation.…”

Section: Introductionmentioning

confidence: 99%

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Thalassemia carrier status and groundwater iron: Implication for iron supplementation program for children in Bangladesh

Rahman,

Lee,

Khan

et al. 2023

Journal of Public Health Research

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Background: Thalassemia, a congenital disorder of hemoglobin synthesis is characterized by low hemoglobin and high iron status, is prevalent in Bangladesh. Iron, consumed through drinking groundwater also increases the population iron status in Bangladesh. The study examined the effect of iron containing micronutrient powder (MNP) on the hemoglobin and ferritin status in Bangladeshi children with thalassemia and their non-thalassemia peers exposed to a high concentration of iron from drinking groundwater. Design and methods: Three hundred twenty-seven children aged 2–5 years were recruited for an MNP efficacy trial. A sub sample ( n = 222) were screened for thalassemia. Hemoglobin and ferritin levels were measured in children with and without thalassemia. Intake of iron from the key sources—diet, groundwater and MNP was measured. Mann Whitney and t-test were employed to compare the groups. Results: Hemoglobin concentration of the children with thalassemia at the endpoint remained unchanged relative to the baseline; 11.56 ± 0.59 g/dL (Endpoint) versus 11.6 ± 0.54 g/dL (Baseline), p = 0.83. In children without thalassemia hemoglobin tended to increase; 12.54 ± 0.72 g/dL (Endpoint) versus 12.41 ± 0.72 g/dL (baseline), p = 0.06. Baseline reserve of body iron was significantly ( p = 0.03) higher in thalassemia carriers (594 gm) compared to their non-carrier peers (558 gm). The increase of the infection-adjusted ferritin from baseline to the endpoint was 7.37% ( p = 0.7) and 10.17% ( p = 0.009) in the carrier and non-carrier groups respectively. Conclusions: In Bangladesh, the coexistence of thalassemia and the exposure to a high concentration of iron from drinking groundwater renders anemia prevention program with a low iron MNP potentially lesser hazardous to the thalassemia carriers.

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Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

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Thalassemia carrier status and groundwater iron: Implication for iron supplementation program for children in Bangladesh

Rahman,

Lee,

Khan

et al. 2023

Journal of Public Health Research

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“…The family Lythraceae comprises small to large trees, shrubs, perennials, and annual herbs adapted to a wide variety of vegetation types, including mangrove swamps, coastal dunes, freshwater marshes, and shallow waters of ponds and rivers in Bangladesh. Hooker (1886) described 19 species under four genera, and Prain (1903) described 14 species under three genera; Khanam (2009) and Rahman (2009) compiled 24 species from six genera from the political boundary of Bangladesh. Heinig (1925) reported 14 species under four genera from the Chittagong region.…”

Section: Introductionmentioning

confidence: 99%

Three new records of lythraceae in the flora of Bangladesh

Rani,

Khan,

Uddin

et al. 2024

Bangladesh J. Plant Taxon

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In the course of studying the family Lythraceae of Bangladesh in 2023–2024, some specimens of the family were found to be different than those of any other species of this family reported so far from this country. After a critical examination, these specimens have been identified as Ammannia auriculata, Rotala ramosior, and Rotala malampuzhensis of the Lythraceae. These species are new to the flora of Bangladesh. A detailed taxonomic description, including data on ecology, distribution, and use, a list of representative specimens examined, and illustrations have been provided for each species. Bangladesh J. Plant Taxon. 31(1): 15-24, 2024 (June)

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“…I recognize your ability to write novels’ (cited in Bhavsar et al, 2011: 70). Once Men and Rivers was on the English literature curriculum of major universities in India and was the first literary text by an Indian to be taught in the country along with those by English writers (Rahman, 2005: 71). According to Amartya Sen (2021: 31), who read the novel when he was at high school, it ‘was a much-read—and much-discussed—book … and the issues it raised received widespread attention.…”

Section: Introductionmentioning

confidence: 99%

Climate Migration in Humayun Kabir’s Men and Rivers: the Padma and Faridpur

Hasan

2023

South Asia Research

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The intensely precarious integration in many parts of Bangladesh between life, rivers and water has been reflected in the country’s river novels that describe the experiences of fishermen and riparian peasants. Among river systems in Bangladesh, the Padma (the Ganges in India) has inspired the greatest number of artists and their writing. Humayun Kabir’s Men and Rivers (1945) stands out as a climate document on the life of the peasantry, whose survival and livelihoods are entwined with this river. However, this novel has remained inadequately known and has not garnered sufficient critical attention in recent years. Filling a lacuna in South Asian literary studies, and combining such studies with climate change discourses, this article discusses Kabir’s novel as a document depicting the environmental challenges faced in Bangladesh, exploring why this literary work has not received prominent coverage.

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Prevalence of Iron Deficiency in Thalassemia Trait: A study in BSMMU, Dhaka

Abstract: Background: Thalassemia is considered the most common genetic disorder worldwide and about 7% of world populations are carriers. A vast majority of such cases have iron deficiency.

Cited by 5 publications

References 6 publications

Thalassemia carrier status and groundwater iron: Implication for iron supplementation program for children in Bangladesh

Thalassemia carrier status and groundwater iron: Implication for iron supplementation program for children in Bangladesh

Three new records of lythraceae in the flora of Bangladesh

Climate Migration in Humayun Kabir’s Men and Rivers: the Padma and Faridpur

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