Prevalence of Iron Deficiency Anemia in Hemodialysis patients at NIKD

Amjad, Ali Imran; Usmani, Saad Z.; Pasha, H. H.; Khan, Wajid; Qamar, Mohammad Aadil; Mustafa, Zia Ul; Ather, U.; Zulfiqar, S.; Habib, Sonia

doi:10.53350/pjmhs211561192

Cited by 1 publication

(1 citation statement)

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“…Most of our study patients were on twice-per-week dialysis, depicting a significant association with anemia, which is also comparable with the published data by Sabir et al [ 20 ], in which twice-per-week dialysis was observed in 75% of study patients. The possible cause of anemia with the increased frequency of dialysis per week may be blood loss, which usually gets retained in the dialyzer machine [ 30 ]. Furthermore, our study results have represented the duration of hemodialysis and evaluated the association of anemia with every additional month in the duration of hemodialysis in ESRD patients.…”

Section: Discussionmentioning

confidence: 99%

Association of Anemia with Parathyroid Hormone Levels and Other Factors in Patients with End-Stage Renal Disease Undergoing Hemodialysis: A Cross-Sectional, Real-World Data Study in Pakistan

Bukhari

Ahmad

Noorin³

et al. 2023

International Journal of Clinical Practice

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End-stage renal disease (ESRD) patients are mostly managed with maintenance hemodialysis (MHD). ESRD patients on MHD also present with many complications, such as anemia, hyperparathyroidism, and hepatitis prevalence. This study depicts the real-world scenario of anemia among MHD and end-stage renal disease patients in the Pakistani population. A retrospective, multicentric, and real-world data analytical study was conducted at 4 dialysis centers in Pakistan. The study had a sample size of n = 342 patients on maintenance hemodialysis. The data were gathered from the medical records of patients. Data analysis was performed using STATA Version 16. Statistical significance was gauged at a 0.05 level of significance. According to our results, the mean age of the patients was 45 (±15) years. Most of the patients were male (n = 234, 68.4%), whereas 58.1% of the patients were maintained on twice-weekly hemodialysis. The most commonly reported comorbidities were hypertension and diabetes mellitus. The frequency of dialysis ( P < 0.01) and comorbidities ( P = 0.009) had a significant association with anemia in MHD patients. The majority of the patients had hyperparathyroidism (52%) with anemia. Upon performing binary logistic regression, multivariate analysis displayed a similar odds value for having anemia in patients with every additional month in the duration of hemodialysis (OR 1.01, P = 0.001), the odds of anemic patients having a positive antihepatitis-C antibody (OR 2.22, P = 0.013), and the odds of having anemia in patients in the age category below 45 years (OR 1.93, P = 0.013). In conclusion, the study results depict that every additional month in the duration of hemodialysis, age (<45 years), and positive anti-HCV antibody status, these variables were more likely to have anemia in our study MHD patients. While in our final multivariate model, no statistically significant association was observed between hyperparathyroidism and anemia.

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Section: Discussionmentioning

confidence: 99%