Prevalence of inflammatory bowel disease in the Australian general practice population: A cross-sectional study

Busingye, Doreen; Pollack, Allan; Chidwick, Kendal

doi:10.1371/journal.pone.0252458

Cited by 24 publications

(24 citation statements)

References 20 publications

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“…It has a high recurrence rate and unpredictable disease course. Recent studies have shown an increased global trend in the prevalence of CD in Western countries,[ 1 2 3 4 ] Asia,[ 5 6 ] and the Arab world. [ 7 ] The incidence of CD is also increasing in Saudi Arabia.…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics of Crohn's disease in a cohort from Saudi Arabia

Qari

2022

Saudi J Med Med Sci

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Objective: In Saudi Arabia, there are limited studies on the clinical characteristics of patients specifically with Crohn's disease (CD). This study was conducted to describe the clinical characteristics of CD at a tertiary care center in Jeddah, Saudi Arabia. Methods: This retrospective study included all patients aged >14 years who had a definitive diagnosis of CD and were managed at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between 2012 and 2018. Data were collected for the following categories: clinical, laboratory, radiological, histological features at presentation, and disease-related complications. Results: The study included 245 newly diagnosed CD patients, aged 14–73 years (median: 26.3 years). All subjects presented with abdominal pain. Majority of the patients (59.7%) received a definitive diagnosis of CD >3 months after the onset of symptoms; 15.1% were initially suspected to have intestinal tuberculosis. Diarrhea and bleeding per rectum were reported in 60.8% and 49.7% of the patients, respectively. Sacroiliitis was the most frequent extraintestinal manifestations (11.4%). In terms of disease location, the terminal ileum (L1) was the most affected area (46.9%). Twenty-five patients had perianal disease, of which 40% had complex fistulae and 36% had perianal abscesses. The majority had hemoglobin levels >10 g/dl (74.1%), decreased serum iron (69.6%) and ferritin (50.5%) levels, and elevated erythrocyte sedimentation rate (68.2%) and C-reactive protein (82.2%). Conclusions: The majority of the patients in our cohort presented with the characteristic quartet of abdominal pain, weight loss, fever, and diarrhea. This study also found a significant number of patients with CD in Saudi Arabia experience diagnostic delay, which may contribute to disease morbidity and complications. These findings highlight the need for future studies to determine factors influencing this diagnostic delay.

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Section: Introductionmentioning

confidence: 99%

Clinical characteristics of Crohn's disease in a cohort from Saudi Arabia

Qari

2022

Saudi J Med Med Sci

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“…[1,4,[12][13][14][15][16][17] While the age of involvement was among older groups compared with published results from Australia (52 years). [18] Which might indicate the difference on the population constitution and demographical pyramid.…”

Section: Balanced Ptn Intakementioning

confidence: 99%

Assessment of nutrition and dietary pattern in IBD patients

Khalidy¹,

Jasim

Hasan³

2022

ijhs

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Background: Inflammatory bowel diseases are chronic debilitating illnesses, nearly 3,9 million females and nearly 3,0 million males are living with IBD worldwide and the number of prevalent cases is on the rise. Malnutrition is not uncommon and is a grave complication that negatively impacts various clinical outcomes as it responsible for chronic weight loss. The current study aims to assess the nutritional status of IBD patients. Patients and methods: A cross sectional study was conducted in Medical city hospital for a period of 6 months, the study included 201 IBD patients were chosen randomly upon their entry to Gastrointestinal outpatient clinic (every 5th patient), patients were interviewed, their files were checked, data were collected and their current nutritional intake were logged into excel sheet, Subjective Global Assessment (SGA) nutritional assessment were done for each patient. In all statistical analysis, P value ≤0.05 is considered significant. Results: More than half 105 (52.2%) of the patients had UC and the remaining 96(47.8%) had CD.

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“…Crohn's disease is a chronic inflammatory bowel disease that occurs in a genetically susceptible individual in response to an unknown environmental stimulus. The incidence in Western populations is increasing and the prevalence in Australia has been estimated at 306 per 100 000 3 . It is estimated that 80% of patients with Crohn's disease require surgery at some point in their life 2 .…”

Section: Figmentioning

confidence: 99%

“…The incidence in Western populations is increasing and the prevalence in Australia has been estimated at 306 per 100 000. 3 It is estimated that 80% of patients with Crohn's disease require surgery at some point in their life. 2 After surgery, endoscopic recurrence (ER) is common with up to 90% of patients found to have ER at 12 months.…”

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confidence: 99%