Prevalence of infections and antimicrobial use in the acute-care hospital setting in the Middle East: Results from the first point-prevalence survey in the region

Alothman, Adel; Thaqafi, Abdulhakeem Al; Ansary, Adel Al; Zikri, Ahmed; Fayed, Akram M.; Khamis, Faryal; Salman, Jameela Al; Dabal, Laila Al; Khalife, Natasha; Al-Musawi, Tariq; Zein, Said El; Kotb, Ramy El Mahdy; Ghoneim, Yasser; Kanj, Souha S.

doi:10.1016/j.ijid.2020.09.1481

Cited by 16 publications

(21 citation statements)

References 26 publications

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“…Among the Enterobacterales 3GCR organisms have reached more than 60% in E. coli and Klebsiella spp. [ 30 , 31 , 32 , 33 ] and carbapenem resistance has fluctuated between 10 to 30% [ 30 , 31 , 32 , 33 ]. P. aeruginosa resistant to carbapenems has been highly reported from some of the Levant and North African Arab countries (more than 50%), while reported to a lesser extent in the Gulf [ 14 , 33 ].…”

Section: Amr In the Arab World Before Covid-19mentioning

confidence: 99%

“…The production of metallo-β-lactamases (mostly VIM and IMP) has been the most important mechanism of carbapenem resistance in P. aeruginosa throughout the Arab League countries [ 14 , 25 , 33 ]. Regarding Gram-positive bacteria, Staphylococcus aureus isolates have shown high methicillin resistance percentage of around 50%, while vancomycin resistance ranged between 0 and 5% [ 30 , 31 , 32 ]. In addition, penicillin non-susceptibility among Streptococcus pneumoniae has been frequently reported in the Middle East (50%) [ 14 , 32 ].…”

Section: Amr In the Arab World Before Covid-19mentioning

confidence: 99%

“…Most Arab countries have produced AMR surveillance reports and many of them have reported their data to the GLASS [ 6 , 34 ]. Yet, the majority of the AMR data is generated by hospital laboratories and therefore may be more biased towards AMR in nosocomial organisms [ 30 , 31 , 32 ]. Several reports describe the AMS efforts in the Arab world [ 29 , 40 , 41 ] showing the successful implementation of stewardship programs to promote appropriate antibiotic use.…”

Section: Amr In the Arab World Before Covid-19mentioning

confidence: 99%

“…High proportions of carbapenem resistance in Acinetobacter spp. have been varying between 70 and 80% in the Levant, Gulf, and Egypt[30][31][32][33]. Among the Enterobacterales 3GCR organisms have reached more than 60% in E. coli and Klebsiella spp [30][31][32][33].…”

mentioning

confidence: 99%

“…have been varying between 70 and 80% in the Levant, Gulf, and Egypt[30][31][32][33]. Among the Enterobacterales 3GCR organisms have reached more than 60% in E. coli and Klebsiella spp [30][31][32][33]. and carbapenem resistance has fluctuated between 10 to 30%[30][31][32][33].…”

mentioning

confidence: 99%

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Challenges to Antimicrobial Stewardship in the Countries of the Arab League: Concerns of Worsening Resistance during the COVID-19 Pandemic and Proposed Solutions

et al. 2021

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The COVID-19 pandemic is expected to worsen the global problem of antimicrobial resistance (AMR). There is a heightened interest in understanding this effect and to develop antimicrobial stewardship (AMS) interventions accordingly to curb this threat. Our paper aims to evaluate the potential magnitude of COVID-19 on AMR and AMS with a focus on the countries of the Arab league, given the social, political, and economic environments. We also evaluate obstacles in applying the rational use of antibiotics, monitoring resistance trends in the midst of the pandemic, and evaluating the impact of the economic crisis in some countries. We aim to raise awareness about the potential effects of antibiotic overuse during the pandemic and to propose practical approaches to tackle this issue.

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Section: Amr In the Arab World Before Covid-19mentioning

confidence: 99%

Section: Amr In the Arab World Before Covid-19mentioning

confidence: 99%

Section: Amr In the Arab World Before Covid-19mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Challenges to Antimicrobial Stewardship in the Countries of the Arab League: Concerns of Worsening Resistance during the COVID-19 Pandemic and Proposed Solutions

et al. 2021

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A Narrative Review of Healthcare-Associated Gram-Negative Infections Among Pediatric Patients in Middle Eastern Countries

et al. 2023

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Introduction: Gram-negative bacteria (GNB) have become prominent across healthcare and community settings due to factors including lack of effective infection control and prevention (ICP) and antimicrobial stewardship programs (ASPs), GNB developing antimicrobial resistance (AMR), and difficulty treating infections. This review summarizes available literature on healthcare-associated infections (HAIs) in Middle Eastern pediatric patients. Methods: Literature searches were performed with PubMed and Embase databases. Articles not reporting data on GNB, HAIs, pediatric patients, and countries of interest were excluded.Results: The searches resulted in 220 publications, of which 49 met the inclusion criteria and 1 additional study was identified manually. Among 19 studies across Egypt reporting GNB prevalence among pediatric patients, Klebsiella species/K. pneumoniae and Escherichia coli were typically the most common GNB infections;

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Antimicrobial therapy, resistance, and appropriateness in healthcare-associated and community-associated infections; a point prevalence survey

Alsaedi

El-Saed

Althaqafi

et al. 2022

Journal of Infection and Chemotherapy

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Prevalence of infections and antimicrobial use in the acute-care hospital setting in the Middle East: Results from the first point-prevalence survey in the region

Cited by 16 publications

References 26 publications

Challenges to Antimicrobial Stewardship in the Countries of the Arab League: Concerns of Worsening Resistance during the COVID-19 Pandemic and Proposed Solutions

Challenges to Antimicrobial Stewardship in the Countries of the Arab League: Concerns of Worsening Resistance during the COVID-19 Pandemic and Proposed Solutions

A Narrative Review of Healthcare-Associated Gram-Negative Infections Among Pediatric Patients in Middle Eastern Countries

Antimicrobial therapy, resistance, and appropriateness in healthcare-associated and community-associated infections; a point prevalence survey

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