Prevalence of Impaired Fasting Glucose and Its Relationship With Cardiovascular Disease Risk Factors in US Adolescents, 1999–2000

Williams, Desmond E.; Cadwell, Betsy L.; Cheng, Yiling J.; Cowie, Catherine C.; Gregg, Edward W.; Geiss, Linda S.; Engelgau, Michael M.; Narayan, K.M. Venkat; Imperatore, Giuseppina

doi:10.1542/peds.2004-2001

Cited by 160 publications

(148 citation statements)

References 27 publications

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“…Even though the prevalence of DM2 in people under 20 years of age has been reported as 0.22% in other countries 35 , we did not find any cases in our sample, probably due to limited power. We did find, however; a surprisingly high prevalence of IFG in adult participants (13.6%), actually higher than that reported for North Americans under age 20 (7.0%) 36 , but unlike the North American report, we found no significant difference between genders.…”

Section: Discussioncontrasting

confidence: 99%

Cardiovascular risk factors and metabolic syndrome in a population of young students from the National University of Colombia

Feliciano-Alfonso¹,

Mendivil²,

Ariza³

et al. 2010

Rev. Assoc. Med. Bras.

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SummaryObjective. To estimate prevalence and distribution of cardiovascular risk factors and Metabolic Syndrome (MS) in young individuals admitted to the National University of Colombia in Bogotá.MethOds. An analytic cross-sectional study was conducted in a sample of 249 individuals of both genders aged 15 to 20 years. A questionnaire was personally administered to collect demographic, socioeconomic, smoking, perinatal, and women's health data. Anthropometric measurements, blood pressure, and a fasting blood sample were taken. Prevalence of MS was determined and compared using criteria from several qualified institutions. Results. We found a high prevalence of smoking (18.9%), arterial prehypertension (14.1%) and overweight (11.2%), 9.2% of study participants had prediabetes, and the most frequent dyslipidemia was low HDL cholesterol (13.3%). Alcoholic beverage consumption was declared by 60.6% of study participants. Body mass index was associated with significant increases in blood pressure, LDL cholesterol and plasma triglyceride levels. Gestational age at birth was inversely associated with presence of low HDL cholesterol levels and high blood pressure. Prevalence of the MS varied markedly according to the definition employed: 9.2% using REGODCI (Research Group on Diabetes and Chronic Illnesses) criteria, 2% using IDF (International Diabetes Federation) criteria, and 2.4% using AHA (American Heart Association) criteria. cOnclusiOn. The encountered prevalence of modifiable cardiovascular risk factors justifies promotion of therapeutic lifestyle changes among this age group in Colombia. Further harmonization of MS criteria in young individuals is needed. caRdiOvasculaR Risk factORs and MetabOlic syndROMe in a pOpulatiOn Of yOung students fROM the natiOnal univeRsity Of cOlOMbia jOhn edwin felicianO-alfOnsO 1* , caRlOs OliMpO Mendivil 2 , iván daRíO sieRRa aRiza 3 , claRa eugenia péRez 4 Study conducted at

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Section: Discussioncontrasting

confidence: 99%

Cardiovascular risk factors and metabolic syndrome in a population of young students from the National University of Colombia

Feliciano-Alfonso¹,

Mendivil²,

Ariza³

et al. 2010

Rev. Assoc. Med. Bras.

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“…8 Several studies suggest that the long-term damage of end-organs associated with diabetes may start in prediabetes. [9][10][11] In 2012, United Healthcare reported in Health Affairs that adults with diabetes have an average annual health care expenditure of $11,700 per person, whereas adults without diabetes have an average annual expenditure per person of $4400. 12 …”

Section: Introductionmentioning

confidence: 99%

Prediabetes and Lifestyle Modification: Time to Prevent a Preventable Disease

Tuso

2014

TPJ

193

143

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“…The latter has been ascribed to different factors such as insulin resistance, activation of the sympathetic nervous system and an abnormal production of substances by adipose tissue. 6 Several papers have reported that office BP levels correlate with metabolic and inflammatory markers in children as well as in adults; [7][8][9][10][11] however, the precise mechanisms involved in starting and maintaining childhood obesity-related hypertension in the office environment, and even more so in ambulatory conditions, are still unknown. Further insight into the pathophysiology of hypertension affecting young obese people can be obtained by exploring the relation between BP levels measured with ambulatory BP monitoring (ABPM) and a number of factors that might be involved in their elevation.…”

Section: Introductionmentioning

confidence: 99%

Sympathoadrenergic and metabolic factors are involved in ambulatory blood pressure rise in childhood obesity

et al. 2007

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We investigated in a young Italian obese population, the relationship between ambulatory BP (ABP) and several pathophysiological factors linking obesity to hypertension. A total of 89 obese children and adolescents underwent a 24-h ambulatory BP monitoring (ABPM) and an oral glucose tolerance test. The circulating levels of insulin, lipids, uric acid, C-reactive protein, interleukin-6, renin and aldosterone and the 24-h urinary levels of epinephrine, norepinephrine and albumin excretion rate were measured. Nine percent of subjects had daytime sustained hypertension (SH), 26 % night-time hypertension and 11 % a non-dipping pattern. SH subjects compared to those with sustained normotension (SN) were more obese (Po0.05), with a more frequent family history of hypertension (Po0.05), higher urinary catecholamine (Po0.05) and heart rate values (Po0.05) after adjustment for standard deviation score (SDS) of body mass index (BMI) and sex. Subjects with night-time hypertension compared to those with night-time normotension were more obese (Po0.0001), with a higher prevalence of impaired glucose tolerance (Po0.05) and metabolic syndrome (Po0.05) and higher 2-h glucose (Po0.05), uric acid (Po0.05) and triglycerides (Po0.05). In multivariate regression analysis, daytime systolic BP (SBP) remained independently correlated with urinary norepinephrine and SDS-BMI (Po0.05 for both), daytime diastolic BP (DBP) with waist circumference (Po0.05) and night-time SBP and DBP with SDS-BMI (Po0.01 for both). The risk of having systolic and diastolic hypertension increased with the increase in SDS-BMI and waist circumference, respectively. In conclusion, in our cohort of obese children and adolescents, daytime and night-time hypertension were associated with activation of the sympathoadrenal system and worst metabolic conditions, respectively.

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Prevalence of Impaired Fasting Glucose and Its Relationship With Cardiovascular Disease Risk Factors in US Adolescents, 1999–2000

Cited by 160 publications

References 27 publications

Cardiovascular risk factors and metabolic syndrome in a population of young students from the National University of Colombia

Cardiovascular risk factors and metabolic syndrome in a population of young students from the National University of Colombia

Prediabetes and Lifestyle Modification: Time to Prevent a Preventable Disease

Sympathoadrenergic and metabolic factors are involved in ambulatory blood pressure rise in childhood obesity

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